Browsing by Issue Date, starting with "2016-12-09"

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A Sliced Inverse Regression (SIR) Decoding the Forelimb Movement from Neuronal Spikes in the Rat Motor Cortex
(2016-12-09)
Yang, Shih-Hung
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Chen, You-Yin
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Lin, Sheng-Huang
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Liao, Lun-De
;
Lu, Henry Horng-Shing
Several neural decoding algorithms have successfully converted brain signals into commands to control a computer cursor and prosthetic devices. A majority of decoding methods, such as population vector algorithms (PVA), optimal linear estimators (OLE), and neural networks (NN), are effective in predicting movement kinematics, including movement direction, speed and trajectory but usually require a large number of neurons to achieve desirable performance. This study proposed a novel decoding algorithm even with signals obtained from a smaller numbers of neurons. We adopted sliced inverse regression (SIR) to predict forelimb movement from single-unit activities recorded in the rat primary motor (M1) cortex in a water-reward lever-pressing task. SIR performed weighted principal component analysis (RCA) to achieve effective dimension reduction for nonlinear regression. To demonstrate the decoding performance, SIR was compared to PVA, OLE, and NN. Furthermore, RCA and sequential feature selection (SFS) which are popular feature selection techniques were implemented for comparison of feature selection effectiveness. Among SIR, PVA, OLE, PCA, SFS, and NN decoding methods, the trajectories predicted by SIR (with a root mean square error, RMSE, of 8.47 +/- 1.32 mm) was closer to the actual trajectories compared with those predicted by PVA (30.41 +/- 11.73 mm), OLE (20.17 +/- 6.43 mm), PCA (19.13 +/- 0.75 mm), SFS (22.75 +/- 2.01 mm), and NN (16.75 +/- 2.02 mm). The superiority of SIR was most obvious when the sample size of neurons was small. We concluded that SIR sorted the input data to obtain the effective transform matrices for movement prediction, making it a robust decoding method for conditions with sparse neuronal information.
雲端商機　谷歌App Maker
(2016-12-11)
何書馨
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Department of Communication and Technology
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傳播與科技學系
谷歌宣布推出應用程式開發工具App Maker，此軟體將整合G Suite各式雲端服務，客製化打造符合企業需求的內部軟體。
無線充電　打破傳統限制
(2016-12-11)
何家沂
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Department of Communication and Technology
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傳播與科技學系
介紹無線充電技術、應用、和未來發展。
譚光鼎　教育之路一定永定
(2016-12-11)
范晨星
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Department of Communication and Technology
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傳播與科技學系
這是一個描述譚光鼎對教育的夢想、理解與熱愛的故事。
總編輯的話
(2016-12-11)
陳昱彣
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Department of Communication and Technology
;
傳播與科技學系
喀報第255期頭題為「性別霸凌荊棘裡的玫瑰」，探討校園性別議題。另外有多篇醫療健康方面的科技新知，讓讀者能由淺入深認識新科技。
高齡駕駛人　上路行不行
(2016-12-11)
陳奕璇
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Department of Communication and Technology
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傳播與科技學系
2017年1月「高齡駕駛人駕駛執照管理制度」將正式實施，故探討新制度之利弊。
研發替代役　安全冒險的路
(2016-12-11)
王廷瑄
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Department of Communication and Technology
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傳播與科技學系
透過分析資方與勞方的雙方觀點，探討研替制度的沿革與爭議。
單
(2016-12-11)
張巧宜
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Department of Communication and Technology
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傳播與科技學系
以單身心境為主題的古詩創作。
BNCT　肝癌治療曙光
(2016-12-11)
劉以寧
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Department of Communication and Technology
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傳播與科技學系
BNCT，硼中子捕獲療法，於清大發展出治療癌症的療法，是醫療新曙光。
蔣月惠　為社會弱勢奮鬥
(2016-12-11)
張博倫
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Department of Communication and Technology
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傳播與科技學系
介紹社福團體「羅騰園」的理事長蔣月惠，三十年來投入羅騰園的歷程。
正反論戰　大麻除罪之爭
(2016-12-11)
郭宜婷
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Department of Communication and Technology
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傳播與科技學系
今年11月美國三個州公投通過大麻作為娛樂使用，使大麻除罪化這項議題在國際社會引起高度關注。
技術革新　打造智慧感知衣
(2016-12-11)
韓舒容
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Department of Communication and Technology
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傳播與科技學系
工研院利用奈妙脈衝及奈米銀線技術，成功研發出可水洗、不必服貼、具有高精確度的「iSmartweaR智慧感知衣」。
新足踝護具　防腳踝慢性病
(2016-12-11)
張芳語
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Department of Communication and Technology
;
傳播與科技學系
顛覆傳統護具單純防止再次扭傷，新式足踝護具增加防止慢性病、治療腳踝扭傷等功能。
性別霸凌　荊棘裡的玫瑰
(2016-12-11)
林宥成
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Department of Communication and Technology
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傳播與科技學系
性霸凌不應被大家忽視，加害者與受害者的心理狀態與外在表現，與其解決之道，都應有管道解決。
鹹鹹海風　戀戀永安
(2016-12-11)
何肇耕
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Department of Communication and Technology
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傳播與科技學系
鹹味的海風、伴隨著薩克斯風的音樂，品嘗著的不僅是海產的鮮，同時還有永安的美。
吳孟霖　旅行外的寫作人生
(2016-12-11)
鄭懿君
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Department of Communication and Technology
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傳播與科技學系
熱愛旅行、身兼工程師與作家的吳孟霖，創立了瘋城部落，協助熱愛文字的寫手們勇敢追夢。
GaN-based vertical-cavity surface emitting lasers with sub-milliamp threshold and small divergence angle
(2016-12-12)
Yeh, P. S.
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Chang, C. -C.
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Chen, Y. -T.
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Lin, D. -W.
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Liou, J. -S.
A GaN-based vertical-cavity surface emitting laser (VCSEL) structure featuring a silicon-diffusion-defined current blocking layer for lateral confinement is described. Sub-milliamp threshold currents were achieved for both 3- and 5-mu m-aperture VCSELs under continuous-wave operation at room temperature. The vertical cavity was defined by a top dielectric distributed Bragg reflector (DBR) and a bottom epitaxial DBR. The emission spectrum exhibited a single peak at 411.2 nm with a line-width of 0.4nm and a side mode suppression ratio of more than 10 dB before device packaging. The full-width-at-half-maximum divergence angle of the 3-mu m-aperture VCSEL was as small as approximately 5 degrees which is the lowest number reported. These results implied the 3-mu m-aperture VCSEL was in near single-mode operation. Published by AIP Publishing.
Perceived Occupational Stress is associated with Decreased Cortical Activity of the Prefrontal Cortex: A Multichannel Near-infrared Spectroscopy Study
(2016-12-13)
Chou, Po-Han
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Lin, Wei-Hao
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Hung, Chao-An
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Chang, Chiung-Chih
;
Li, Wan-Rung
Despite an increasing number of reports on the associations between chronic occupational stress and structural and functional changes of the brain, the underlying neural correlates of perceived occupational stress is still not clear. Perceived stress reflects the extents to which situations are appraised as stressful at a given point in one's life. Using near-infrared spectroscopy, we investigated the associations between perceived occupational stress and cortical activity over the bilateral frontotemporal regions during a verbal fluency test. Sixty-eight participants (17 men, 51 women), 20-62 years of age were recruited. Perceived occupational stress was measured using the Chinese version of Job Content Questionnaire, and the Chinese version of the Copenhagen Burnout Inventory. We found statistically significant negative associations between occupational burnout and brain cortical activity over the fronto-polar and dorsolateral prefrontal cortex during the VFT (r = -0.343 to -0.464). In conclusion, our research demonstrated a possible neural basis of perceived occupational stress that are distributed across the prefrontal cortex.
Pleiotropic Effects of Myocardial MMP-9 Inhibition to Prevent Ventricular Arrhythmia
(2016-12-14)
Weng, Ching-Hui
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Chung, Fa-Po
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Chen, Yao-Chang
;
Lin, Shien-Fong
;
Huang, Po-Hsun
Observational studies have established a strong association between matrix metalloproteinase-9 (MMP-9) and ventricular arrhythmia. However, whether MMP-9 has a causal link to ventricular arrhythmia, as well as the underlying mechanism, remains unclear. Here, we investigated the mechanistic involvement of myocardial MMP-9 in the pathophysiology of ventricular arrhythmia. Increased levels of myocardial MMP-9 are linked to ventricular arrhythmia attacks after angiotensin II (Ang II) treatment. MMP-9-deficient mice were protected from ventricular arrhythmia. Increased expressions of protein kinase A (PKA) and ryanodine receptor phosphorylation at serine 2808 (pS2808) were correlated with inducible ventricular arrhythmia. MMP-9 deficiency consistently prevented PKA and pS2808 increases after Ang II treatment and reduced ventricular arrhythmia. Calcium dynamics were examined via confocal imaging in isolated murine cardiomyocytes. MMP-9 inhibition prevents calcium leakage from the sarcoplasmic reticulum and reduces arrhythmia-like irregular calcium transients via protein kinase A and ryanodine receptor phosphorylation. Human induced pluripotent stem cell-derived cardiomyocytes similarly show that MMP-9 inhibition prevents abnormal calcium leakage. Myocardial MMP-9 inhibition prevents ventricular arrhythmia through pleiotropic effects, including the modulation of calcium homeostasis and reduced calcium leakage.
Cobalt Oxide (CoOx) as an Efficient Hole-Extracting Layer for High Performance Inverted Planar Perovskite Solar Cells
(2016-12-14)
Shalan, Ahmed Esmail
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Oshikiri, Tomoya
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Narra, Sudhakar
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Elshanawany, Mahmoud M.
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Ueno, Kosei
CoOx is a promising hole-extracting layer (HEL) for inverted planar perovskite solar cells with device configuration ITO/CoOx/CH3NH3PbI3/PCBM/Ag. The devices fabricated according to a simple solution procedure showed the best photovoltaic performance attaining power conversion efficiency (PCE) of 14.5% under AM 1.5 G 1 sun irradiation, which is significantly superior to those of materials fabricated with a traditional HEL such as PEDOT:PSS (12.2%), NiOx (10.2%), and CuOx (9.4%) under the same experimental conditions. We characterized the chemical compositions with XPS, crystal structures with XRD, and film morphology with SEM/AFM techniques. Photoluminescence (PL) spectra and the corresponding PL decays for perovskite deposited on varied HEL films were recorded to obtain the hole-extracting characteristics, for which the hole extracting times show the order CoOx (2.8 ns) < PEDOT:PSS (17.5 ns) < NiOx (22.8 ns) < CuOx (208.5 ns), consistent with the trend of their photovoltaic performances. The reproducibility and enduring stability of those devices were examined to show the outstanding long-term stability of the devices made of metal oxide HEL, for which the CoOx device retained PCE approximate to 12% for over 1000 h.