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Item type:Item, Inverse magnetic catalysis in the soft-wall model of AdS/QCD(2017-02-07) ;Li, Danning ;Huang, Mei ;Yang, Yi ;Yuan, Pei-Hung電子物理學系Magnetic effects on chiral phase transition have been investigated in a modified soft-wall AdS/QCD model, in which the dilaton field is taken to be negative at the ultraviolet region and positive at the infrared region as in Phys. Rev. D 93 (2016) 101901 and JHEP 04 (2016) 036. The magnetic field is introduced into the background geometry by solving the Einstein-Maxwell system. After embedding the magnetized background geometry into the modified soft-wall model, the magnetic field dependent behavior of chiral condensate is worked out numerically. It is found that, in the chiral limit, the chiral phase transition remains as a second order at finite magnetic field B, while the symmetry restoration temperature and chiral condensate decrease with the increasing of magnetic field in small B region. When including finite quark mass effect, the phase transition turns to be a crossover one, and the transition temperature still decreases with increasing magnetic field B when B is not very large. In this sense, inverse magnetic catalysis effect is observed in this modified soft-wall AdS/QCD model.Item type:Item, All-electric spin pumping in quantum channels with a single finger-gate capacitor(2017-02-07) ;Wang, L. Y. ;Chu, C. S. ;電子物理學系Department of ElectrophysicsIn this paper, we show that a single finger-gate capacitor (FGC) can generate pure spin pumping in a quantum channel (QC). Two dynamic fields, ac spin-orbit interaction and ac potential energy, both induced by the FGC onto the QC, are the agents driving the spin pumping. Smooth spatial profiles of the two ac fields are taken into account both perturbatively and full numerically for the nonadiabatic spin pumping. Our perturbative approach reveals that the spin-pumping mechanism is resonant sideband processes associated with simultaneous coupling of the two ac fields with traversing carriers. Full sideband-process treatment is carried out numerically by a time-dependent scattering matrix method. The same spin-pumping mechanism holds also for the case of a single finger-gated QC, albeit with smaller pumping amplitudes.Item type:Item, Size-Dependent Optical Properties of Grana Inside Chloroplast of Plant Cells(2017-02-09) ;Uwada, Takayuki ;Huang, Ling-Ting ;Hee, Ping-Yu ;Usman, AnwarMasuhara, HiroshiWell-packed thylakoids known as grana are one of the major functional sites for photosynthesis in algae and plants. Their highly ordered structures can be considered as a few hundred nanometer-sized particles having distinct scattering cross sections from other various macromolecular organizations inside plant cells. With this background we shOw that elastic light scattering imaging and microspectroscopy is an important tool for investigating structure and organisation of grana inside a single chloroplast in plant tells. We have demonstrated this noninvasive method to identify the distribution of grana in intact fresh leaf of robust and rapidly growing Egaria densa, which is also known as Anachris and among the most popular aquarium plants. The scattering efficiency spectra of their individual grana fairly resemble cooperative absorption spectra of porphyrins and carotenoids. We found that the electronic structure of the stacked thylakoids shows granum size-dependence, indicating that size of grana is one of the critical parameters in the regulation of the photochemical functions in the thylakoid.Item type:Item, USE OF KNOWN COMPOUNDS AS D-AMINO ACID OXIDASE INHIBITORS(2017-02-09) ;Yufeng Jane TSENG ;Yu-Li LIU ;Chung-Ming SUN ;Hai-Gwo HWUChih-Min LIUThe invention utilizes virtual screening strategy to seek for current market drugs as anti-schizophrenia therapy drug repurposing. Drug repurposing strategy finds new uses other than the original medical indications of existing drugs. Finding new indications for such drugs will benefit patients who are in needs for a potential new therapy sooner since known drugs are usually with acceptable safety and pharmacokinetic profiles. In this study, repurposing marketed drugs for DAAO inhibitor as new schizophrenia therapy was performed with virtual screening on marketed drugs and its metabolites. The identified and available drugs and compounds were further confirmed with in vitro DAAO enzymatic inhibitory assay.Item type:Item, Comprehensive target capture/next-generation sequencing as a second-tier diagnostic approach for congenital muscular dystrophy in Taiwan(2017-02-09) ;Liang, Wen-Chen ;Tian, Xia ;Yuo, Chung-Yee ;Chen, Wan-ZiKan, Tsu-MinPurpose Congenital muscular dystrophy (CMD) is a heterogeneous disease entity. The detailed clinical manifestation and causative gene for each subgroup of CMD are quite variable. This study aims to analyze the phenotypes and genotypes of Taiwanese patients with CMD as the epidemiology of CMD varies among populations and has been scantly described in Asia. Methods A total of 48 patients suspected to have CMD were screened and categorized by histochemistry and immunohistochemistry studies. Different genetic analyses, including next-generation sequencing (NGS), were selected, based on the clinical and pathological findings. Results We identified 17 patients with sarcolemma-specific collagen VI deficiency (SSCD), 6 patients with merosin deficiency, two with reduced alpha-dystroglycan staining, and two with striking lymphocyte infiltration in addition to dystrophic change on muscle pathology. Fourteen in 15 patients with SSCD, were shown to have COL6A1, COL6A2 or COL6A3 mutations by NGS analysis; all showed marked distal hyperlaxity and normal intelligence but the overall severity was less than in previously reported patients from other populations. All six patients with merosin deficiency had mutations in LAMA2. They showed relatively uniform phenotype that were compatible with previous studies, except for higher proportion of mental retardation with epilepsy. With reduced alpha-dystroglycan staining, one patient was found to carry mutations in POMT1 while another patient carried mutations in TRAPPC11. LMNA mutations were found in the two patients with inflammatory change on muscle pathology. They were clinically characterized by neck flexion limitation and early joint contracture, but no cardiac problem had developed yet. Conclusion Muscle pathology remains helpful in guiding further molecular analyses by direct sequencing of certain genes or by target capture/NGS as a second-tier diagnostic tool, and is crucial for establishing the genotype-phenotype correlation. We also determined the frequencies of the different types of CMD in our cohort which is important for the development of a specific care system for each disease.Item type:Item, PACKAGE STRUCTURE OF A LIGHT-EMITTING DEVICE(2017-02-09) ;Chien-Chung Lin ;Hao-Chung Kuo ;Chin-Wei Sher ;Hau-Vei HanKuo-Ju ChenA light-emitting device packaging structure is provided. The light-emitting device packaging structure includes a substrate, an array of light-emitting devices, an encapsulating layer, scattering particles, and a fluorescent material layer. The array of light-emitting devices is on the substrate. The encapsulating layer covers the array of light-emitting devices. The scattering particles are dispersed in the encapsulating layer. The fluorescent material layer is on the encapsulating layer.Item type:Item, PHOTODETECTING DEVICE AND METHOD OF USING THE SAME(2017-02-09) ;Yuh-Shyong YANG ;Chien-Hung CHENChih-Heng LINA photodetecting device and method of using the same are provided. The photodetecting device includes a transistor, a silicon nano-channel and a filter dye layer. The transistor includes a source, a drain and a gate. The silicon nano-channel connects the source and the drain, and is configured to receive light. The filter dye layer is over a light-receiving surface of the silicon nano-channel.Item type:Item, 薬物組成物およびその製造方法(2017-02-09) ;黄 唯▲ティン▼ ;李 翊綺劉 典謨【課題】薬物組成物およびその製造方法を提供する。【解決手段】複数の親水基と複数の疎水基で変性された両親媒性キトサン誘導体と、前記両親媒性キトサン誘導体に埋め込められ、静電力により前記複数の親水基を吸引する少なくとも一つの親水性薬物と、前記両親媒性キトサン誘導体に埋め込められ、前記複数の疎水基の間にある少なくとも一つの疎水性薬物と、を含む、薬物組成物を提供する。また、複数の親水基と複数の疎水基で変性された両親媒性キトサン誘導体と、少なくとも一つの疎水性薬物と、少なくとも一つの親水性薬物とを溶剤に分散させて混合溶液を形成し、前記混合溶液のpHを前記親水性薬物および前記疎水性薬物が沈殿しない範囲に調整することと、前記混合溶液を少なくとも12時間撹拌し、前記混合溶液のpHを6〜7にすることと、を含む薬物組成物の製造方法を提供する。【選択図】図1Item type:Item, In-situ Multimodal Imaging and Spectroscopy of Mg Electrodeposition at Electrode-Electrolyte Interfaces(2017-02-10) ;Wu, Yimin A. ;Yin, Zuwei ;Farmand, Maryam ;Yu, Young-SangShapiro, David A.We report the study of Mg cathodic electrochemical deposition on Ti and Au electrode using a multimodal approach by examining the sample area in-situ using liquid cell transmission electron microscopy (TEM), scanning transmission X-ray microscopy (STXM) and X-ray absorption spectroscopy (XAS). Magnesium Aluminum Chloride Complex was synthesized and utilized as electrolyte, where non-reversible features during in situ charging-discharging cycles were observed. During charging, a uniform Mg film was deposited on the electrode, which is consistent with the intrinsic non-dendritic nature of Mg deposition in Mg ion batteries. The Mg thin film was not dissolvable during the following discharge process. We found that such Mg thin film is hexacoordinated Mg compounds by in-situ STXM and XAS. This study provides insights on the non-reversibility issue and failure mechanism of Mg ion batteries. Also, our method provides a novel generic method to understand the in situ battery chemistry without any further sample processing, which can preserve the original nature of battery materials or electrodeposited materials. This multimodal in situ imaging and spectroscopy provides many opportunities to attack complex problems that span orders of magnitude in length and time scale, which can be applied to a broad range of the energy storage systems.Item type:Item, Contrast-sensitivity-based evaluation method of a surveillance camera's visual resolution: improvement from the conventional slanted-edge spatial frequency response method(2017-02-10) ;Qin, Zong ;Wong, Po-Jung ;Chao, Wei-Chung ;Lin, Fang-ChengHuang, Yi-PaiVisual resolution is an important specification of a surveillance camera, and it is usually quantified by linewidths per picture height (LW/PH). The conventional evaluation method adopts the slanted-edge spatial frequency response (e-SFR) and uses a fixed decision contrast ratio to determine LW/PH. However, this method brings about a considerable error with respect to subjectively judged results because the perceptibility of the human vision system (HVS) varies with spatial frequency. Therefore, in this paper, a systematic calculation method, which combines the contrast sensitivity function characterizing the HVS and e-SFR, is proposed to solve LW/PH. Eight 720P camera modules in day mode, four 720P modules in night mode, and two 1080P modules in day mode are actually adopted. Corresponding to the three modes, mean absolute error between objective and subjective LW/PH are suppressed to as low as 26 (3.6% of 720P), 27 (3.8% of 720P), and 49 (4.5% of 1080P), while those of the conventional method are 68 (9.4% of 720P), 95 (13.2% of 720P), and 118 (10.9% of 1080P).(C) 2017 Optical Society of AmericaItem type:Item, A Novel Read Scheme for Large Size One-Resistor Resistive Random Access Memory Array(2017-02-10) ;Zackriya, Mohammed, V ;Kittur, Harish M. ;Chin, Albert ;電子工程學系及電子研究所Department of Electronics Engineering and Institute of ElectronicsThe major issue of RRAM is the uneven sneak path that limits the array size. For the first time record large One-Resistor (1R) RRAM array of 128x128 is realized, and the array cells at the worst case still have good Low-/High-Resistive State (LRS/HRS) current difference of 378 nA/16 nA, even without using the selector device. This array has extremely low read current of 9.7 mu A due to both low-current RRAM device and circuit interaction, where a novel and simple scheme of a reference point by half selected cell and a differential amplifier (DA) were implemented in the circuit design.Item type:Item, Ran-dependent TPX2 activation promotes acentrosomal microtubule nucleation in neurons(2017-02-13) ;Chen, Wen-Shin ;Chen, Yi-Ju ;Huang, Yung-An ;Hsieh, Bing-YuanChiu, Ho-ChiehThe microtubule (MT) cytoskeleton is essential for the formation of morphologically appropriate neurons. The existence of the acentrosomal MT organizing center in neurons has been proposed but its identity remained elusive. Here we provide evidence showing that TPX2 is an important component of this acentrosomal MT organizing center. First, neurite elongation is compromised in TPX2-depleted neurons. In addition, TPX2 localizes to the centrosome and along the neurite shaft bound to MTs. Depleting TPX2 decreases MT formation frequency specifically at the tip and the base of the neurite, and these correlate precisely with the regions where active GTP-bound Ran proteins are enriched. Furthermore, overexpressing the downstream effector of Ran, importin, compromises MT formation and neuronal morphogenesis. Finally, applying a Ran-importin signaling interfering compound phenocopies the effect of TPX2 depletion on MT dynamics. Together, these data suggest a model in which Ran-dependent TPX2 activation promotes acentrosomal MT nucleation in neurons.Item type:Item, The structural and electrical comparison of Y2O3 and Ti-doped Y2O3 dielectrics(2017-02-15) ;Lee, Ming Ling ;Kao, Chyuan Haur ;Chen, Hsiang ;Lin, Chan YuChung, Yu TengA Ti-doped Y2O3(Y2Ti2O5) dielectric on polycrystalline silicon followed by rapid thermal annealing results in improved characteristics including a higher effective dielectric constant, higher breakdown electric field, lower electron trapping rate, and larger charge-to-breakdown when compared with Y2O3. The performance of high-k Y2O3 and Y2Ti2O5 dielectrics were investigated using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), capacitance-voltage, and current density-voltage. Incorporating Ti into the Y2O3 dielectric imparts improvements in the structural and electrical performance of the material. The Y2Ti2O5 dielectric with 800 degrees C annealing treatment has the best performance among all the samples tested.Item type:Item, Band-Engineered Local Cooling in Nanoscale Junctions(2017-02-15) ;Hsu, Bailey C. ;Chen, Yu-Chang ;電子物理學系Department of ElectrophysicsThe stability and performance of nanoscale junctions are closely related to the local effective temperature. The local effective temperature is mainly caused by the competition between heating and cooling processes in inelastic electron-phonon scat-tering. Local cooling occurs when the rate of energy in cooling exceeds that in heating. Previous research has been done using either specific potential configuration or an adatom to achieve local cooling. We propose an engineer-able localcooling mechanism in asymmetric two-terminal tunneling junctions, in which one electrode is made of metal, whereas the other is made of a selectable bad-metal, such as heavily-doped polysilicon. The width of energy window of the selectable material, defined as the width covering all possible energy states counting from the conduction band minimum, can be engineered through doping. Interestingly, we have shown that substantial local cooling can be achieved at room temperature when the width of energy window of the low-density electrode is comparable to the energy of the phonon. The unusual local cooling is caused by the narrowed width of energy window, which obstructs the inelastic scattering for heating.Item type:Item, Type-II GaAs0.5Sb0.5/InP Uni-Traveling Carrier Photodiodes With Sub-Terahertz Bandwidth and High-Power Performance Under Zero-Bias Operation(2017-02-15) ;Wun, Jhih-Min ;Chao, Rui-Lin ;Wang, Yu-Wen ;Chen, Yi-HanShi, Jin-WeiWe successfully demonstrate ultrafast uni-traveling carrier photodiodes (PD) with sub-terahertz bandwidth (similar to 170 GHz) and high-power performance under zero bias and at 1.55-mu m optical wavelength operation. By using a type-II (GaAs0.5Sb0.5/InP) absorption-collector interface and inserting an n-type (1 x 1018 cm(-3)) charge layer in the collector, the current blocking (Kirk) effect can be greatly minimized. A stack of undoped Al-x In0.52Ga0.48-x As layers with different Aluminum mole fractions (x: 0.2 to 0.08) and bandgaps is adopted as the collector layer. This graded-bandgap design can provide a built-in electric field and further shorten the internal collector transit time. The demonstrated PD structure achieves a 3-dB optical-to-electrical bandwidth of 170 GHz and subterahertz output power -11.3 dBm at 170 GHz, a record among all the reported zero-bias PDs.Item type:Item, High-Capacity Carrierless Amplitude and Phase Modulation for WDM Long-Reach PON Featuring High Loss Budget(2017-02-15) ;Wei, Chia-Chien ;Chen, Kuan-Zhou ;Chen, Li-Wei ;Lin, Che-YuHuang, Wan-JouThis paper utilizes spectrally efficient carrierless amplitude and phase (CAP) modulation and four wavelength division multiplexing channels in formulation of a high-capacity transmission system. The dispersion and loss associated with a single-mode fiber of 60 km can result in severe power fading and insufficient loss budget, respectively. This study employed high launch power to overcome these issues and thereby achieve long-reach transmission without the need for dispersion compensation or an optical inline amplifier. Modified Volterra filtering is used to deal with the linear and nonlinear distortions within the system. This allowed for the inclusion of cost-effective 10-GHz-class electro-absorption modulators and p-i-n detectors for 4-lambda 224-Gb/s 32-CAP 60-km transmission with a loss budget of 26 dB/channel. The proposed system provides support for the 64 optical network units (ONUs) with downstream transmission of > 3 Gb/s/ONU for future long-reach passive optical networks. We also examined the transmission performance of each channel under various launch powers. Increasing launch power from 9 to 18 dBm/channel increases the loss budget by 9 dB and expands the total capacity by 42%.Item type:Item, 光感測裝置及其應用(2017-02-16) ;楊裕雄 ;陳建宏林志衡本發明提供一種光感測裝置及其應用。光感測裝置包含電晶體、矽奈米通道以及濾光染料層。電晶體包含源極、汲極及閘極。矽奈米通道連接源極與汲極設置用於接收光照。濾光染料層位於矽奈米通道接收光照的表面上。Item type:Item, 發光元件封裝結構(2017-02-16) ;林建中 ;郭浩中 ;佘慶威 ;韓皓惟陳國儒本發明提供一種發光元件封裝結構,其包含基板、發光元件陣列、封膠層、散射粒子以及螢光材料層。發光元件陣列位於基板上。封膠層覆蓋發光二極體陣列。散射粒子散佈於封膠層中。螢光材料層位於封膠層上。Item type:Item, Review of lattice results concerning low-energy particle physics(2017-02-17) ;Aoki, S. ;Aoki, Y. ;Becirevic, D. ;Bernard, C.Blum, T.We review lattice results related to pion, kaon, D- and B-meson physics with the aim of making them easily accessible to the particle-physics community. More specifically, we report on the determination of the light-quark masses, the form factor f(+)(0), arising in the semileptonic K -> pi transition at zero momentum transfer, as well as the decay constant ratio fK / f pi and its consequences for the CKM matrix elements V-us and V-ud. Furthermore, we describe the results obtained on the lattice for some of the low-energy constants of SU(2) L x SU(2) R and SU(3) L x SU(3) R Chiral Perturbation Theory. We review the determination of the B-K parameter of neutral kaon mixing as well as the additional four B parameters that arise in theories of physics beyond the StandardModel. The latter quantities are an addition compared to the previous review. For the heavy-quark sector, we provide results for m(c) and m(b) (also new compared to the previous review), as well as those for D- and B-meson-decay constants, form factors, and mixing parameters. These are the heavy-quark quantities most relevant for the determination of CKM matrix elements and the global CKM unitarity-triangle fit. Finally, we review the status of lattice determinations of the strong coupling constant alpha(s).Item type:Item, 交大e-News第226期-機車遊行嘉年華 2017年丁酉梅竹賽系列活動開跑(2017-02-20) ;國立交通大學秘書室Secretariat