Browsing by Issue Date, starting with "2017-06-12"

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Single-photon avalanche diodes in 0.18-mu m high-voltage CMOS technology
(2017-06-12)
Huang, L. D.
;
Wu, J. Y.
;
Wang, J. P.
;
Tsai, C. M.
;
Huang, Y. H.
We have designed and fabricated high-performance single-photon avalanche diodes (SPADs) by using 0.18-mu m high-voltage CMOS technology. Without any technology customization. the SPADs have low dark-count rate, high photon-detection probability, low afterpulsing probability, and acceptable timing jitter and breakdown voltage. Our design provides a low-cost and high-performance SPAD for various applications. (C) 2017 Optical Society of America
Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach
(2017-06-12)
Hsu, Kai-Cheng
;
Liu, Chang-Yi
;
Lin, Tony Eight
;
Hsieh, Jui-Hua
;
Sung, Tzu-Ying
Histone deacetylases (HDAC) contain eighteen isoforms that can be divided into four classes. Of these isoform enzymes, class IIa (containing HDAC4, 5, 7 and 9) target unique substrates, some of which are client proteins associated with epigenetic control. Class IIa HDACs are reportedly associated with some neuronal disorders, making HDACs therapeutic targets for treating neurodegenerative diseases. Additionally, some reported HDAC inhibitors contain hydroxamate moiety that chelates with zinc ion to become the cofactor of HDAC enzymes. However, the hydroxamate functional group is shown to cause undesirable effects and has poor pharmacokinetic profile. This study used in silico virtual screening methodology to identify several nonhydroxamate compounds, obtained from National Cancer Institute database, which potentially inhibited HDAC4. Comparisons of the enzyme inhibitory activity against a panel of HDAC isoforms revealed these compounds had strong inhibitory activity against class IIa HDACs, but weak inhibitory activity against class I HDACs. Further analysis revealed that a single residue affects the cavity size between class I and class IIa HDACs, thus contributing to the selectivity of HDAC inhibitors discovered in this study. The discovery of these inhibitors presents the possibility of developing new therapeutic treatments that can circumvent the problems seen in traditional hydroxamate-based drugs.
Operando X-ray spectroscopic observations of modulations of local atomic and electronic structures of color switching smart film
(2017-06-14)
Lu, Ying-Rui
;
Wu, Tzung-Zing
;
Chang, Han-Wei
;
Chen, Jeng-Lung
;
Chen, Chi-Liang
Smart windows, which change color in response to external stimuli, are extensively studied owing to their potential technological applications in sensors and their ability to reduce the energy consumed by buildings. Most related studies focus on the optical properties of smart color switching films that can control the transmission of light and that of heat independently. This study examines the vanadium pentoxide thin film as a model system of a color switchable window. A gasochromic thin film of V2O5 is fabricated using sol-gel spin coating. In operando soft X-ray absorption spectroscopy (XAS) at the V L-edge is used to determine the evolutions of the electronic and atomic structures of V2O5 thin film under gasochromic color switching. Analysis of the V K-edge with respect to crystalline structural symmetry and valence requires many reference samples, whereas the V L-edge, which involves V 3d orbitals of various symmetries, can provide information about the atomic/electronic structures without many reference samples. A new gas reaction in situ cell was developed to collect the total-electron-yield XAS. The total-electron-yield signal can provide more accurate information about atomic and electronic structures than can the fluorescence-yield signal, which typically exerts a saturation effect. Analytical results reveal that the gasochromic reaction changes the charge state and causes a local atomic structural deformation of the film. The suggestion has been made that in the reaction, the central vanadium atom within the octahedron moves closer to the basal plane such that the apical V-O bond becomes more symmetrical than the film before gasochromic coloration. Unlike the cell that is used for hard XAS, and for which only cation sites can be studied, this in situ gas cell enables the real-time studies of atomic/electronic structures at gas-solid interfaces from viewpoints of both cation and anion sites.
The preparation, and structural and multiferroic properties of B-site ordered double-perovskite Bi2FeMnO6
(2017-06-14)
Sun, Lin
;
Fang, Yue-Wen
;
He, Jun
;
Zhang, Yuanyuan
;
Qi, Ruijuan
We report the structural, magnetic, and ferroelectric properties of double-perovskite Bi2FeMnO6 in which Fe3+ and Mn3+ cations are present with alternative ordering along the [111] direction. High-flux synchrotron X-ray diffraction and high resolution transmission electron microscopy show that the pseudo-cubic lattice of Bi2FeMnO6 consists of alternatively corner-shared octahedra of FeO6 and MnO6. In the highly ordered Bi2FeMnO6 thin films, the unusual spin-glassy magnetic state is observed below 18 K by a superconducting quantum interference device, and this is ascribed to the magnetic frustration at the [111] Fe3+ and Mn3+ planes as indicated by X-ray magnetic circular dichroism measurements. Combining with the orbital model analysis based on Goodenough-Kanamori-Anderson rules, first-principles calculations and Monte Carlo simulations suggest that magnetic frustration is dominated by the long-range second nearest neighboring antiferromagnetic interactions of Fe3+-Fe3+ and Mn3+-Mn3+ and leads to the surprisingly weak magnetism. On the other hand, robust room-temperature ferroelectricity in Bi2FeMnO6 films is confirmed by piezoelectric force microscopy through electrically switching the polarization state and the ferroelectric retention.
Synthesis of diketopyrrolopyrrole based conjugated polymers containing thieno[3,2-b]thiophene flanking groups for high performance thin film transistors
(2017-06-14)
Peng, Shih-Hao
;
Tu, Wei-Yi
;
Gollavelli, Ganesh
;
Hsu, Chain-Shu
;
應用化學系
New donor-acceptor (D-A) conjugate polymers based on 3,6-bis(2-bromothieno-[3,2-b] thiophen-5-yl)2,5- bis(2-octyldodecyl) pyrrolo[3,4-c]-pyrrole-1,4-(2H, 5H)-dione (Br-TTDPP) combined with three different electron-donating monomers bithiophene (BT), di(2-thienyl) ethene (TVT), and di(selenophene2- yl) ethene (SVS) were synthesized. The optical band gap, electrochemical properties and organic fieldeffect transistor (OFET) device performance of the TTDPP-based polymers were systematically investigated. X-ray diffraction (XRD) was used to evaluate the molecular packing of the TTDPP-based polymers. Among three polymers, TTDPP-SVS showed the smallest d-spacing and the largest distance of 0.372 for pi-pi stacking. In particular, an OTFT having a TTDPP-SVS active layer showed the highest hole mobility of 0.196 cm(2) V-1 s(-1), the lowest threshold voltage down to -3.6 V, and the highest Ion/Ioff ratio of 6.5 x 10(4). This indicates that p-extended SVS significantly improves charge transport properties.
Selective solvent-induced reconstruction in confined space: one-dimensional mesoporous block copolymer structures in cylindrical nanopores
(2017-06-14)
Chang, Chun-Wei
;
Chi, Mu-Huan
;
Ko, Hao-Wen
;
Chu, Chien-Wei
;
Fang, Zhi-Xuan
We investigate the formation of polystyrene-block-poly(methyl methacrylate) (PS-b-PMMA) nanostructures confined in cylindrical nanopores via a novel selective solvent-induced reconstruction process. The key factors of the morphologies of the nanostructures are determined, including the choice of solvents, the molecular weights of the polymers, and the pore diameters of the templates.
Influence of plasma fluorination on p-type channel tin-oxide thin film transistors
(2017-06-15)
Chen, Po-Chun
;
Chiu, Yu-Chien
;
Zheng, Zhi-Wei
;
Cheng, Chun-Hu
;
Wu, Yung-Hsien
This paper describes a high-performance p-type tin-oxide (SnO) thin film transistor (TFT) using fluorine plasma treatment on the SnO active channel layer. The influence of fluorine plasma treatment for this p-type SnO TFT device was also investigated. Through tuning the fluorine plasma power treated on the SnO active channel layer at low temperature, the optimal p-type SnO TFT device exhibits a very high on/off current ratio of 9.6 x 10(6), a field-effect mobility of 2.13 cm(2) V-1 s(-1), a very low subthreshold swing of 106 mV/dec and an extremely low off-state current of 1 pA at a low driven voltage of <3 V. These good characteristics can be attributed to fluorine plasma treatment on p-type SnO channel that reduced crystallized channel roughness and passivated oxygen vacancies and interface traps. This high-performance p-type SnO TFT device using fluorine plasma treatment on the active channel shows great promise for future high-resolution and high-speed display applications. (C) 2016 Elsevier B.V. All rights reserved.
從語言學觀察商標淡化──論產地證明標章之立法妥適性
(交通大學科技法律學院（原名稱：交通大學科技法律研究所）, 2017-06-15)
陳思宇
;
Si-Yu Chen
任何能夠傳遞資訊的載體皆可視為符號，文字、語言、標章皆屬之。本文以「產地證明標章」為中心，分析我國自2011 年商標法修法後，於條文設計上多「依其性質準用」一般商標的規定。基於產地證明標章在各方面皆異於一般商標，因此，在商標侵權態樣之一──淡化（dilution）之規定上，產生準用之困難。本文從產地證明標章之意義、功能為起點，透過 Saussure 符號學分析傳統混淆誤認規範與商標淡化間所侵害之法益有何不同，並提出構成「商標淡化」之要件為何。惟我國實務對於構成商標淡化之要件看法分歧，原因在於對商標淡化保護之法益模糊不清。本文透過語言學上轉喻（metonymy）分析淡化所保護之法益，提出產地證明標章應無一般商標淡化規定之適用，並在最後以經濟學上外部性（externality）之角度，在商標法架構下提出修法建議。
A rapid responding ultraviolet sensor based on multi-parallel aligned ZnO nanowires field effect transistor
(2017-06-15)
Tiong, Teck-Yaw
;
Dee, Chang-Fu
;
Hamzah, Azrul Azlan
;
Goh, Boon Tong
;
Wong, Yuan-Yee
One-dimensional zinc oxide nanowires (ZnO NWs) have been reported to be suitable for UV sensing, but their applications are limited due to restricted surface area which restrains the performance especially in term of response and recovery. In this paper, we fabricate a UV sensor using multi-parallel aligned ZnO NWs based FET in order to overcome the mentioned drawbacks. The sensing characteristics of multi parallel aligned ZnO NWs based FET toward 0.44 mW/cm(2) UV illumination has been examined under depletion and enhancement modes, at ambient conditions. The fabricated UV sensor was found to possess the ability to differentiate UV with different intensity, improved sensitivity (in depletion mode), short response and recovery time (< 1 s), and with high stability. Our paper reports a simple and effective approach for UV sensor fabrication with high responsivity, sensitivity and reproducibility. (C) 2017 Elsevier B.V. All rights reserved.
BRIGHTNESS COMPENSATION CIRCUITRY, AND DISPLAY DEVICE INCLUDING THE SAME
(2017-06-15)
Ya-Hsiang TAI
;
Xuan-Yong LIN
;
Chun-Yi CHANG
A brightness compensation circuitry includes a data-setting switch unit receiving a data-setting signal, a pixel unit including a pixel driving circuit that receives the data-setting signal during a data-input period to generate a driving current, and a compensation circuit receiving the driving current generated by the pixel driving circuit. The compensation circuit controls the data-setting switch unit to conduct or not conduct by determining whether or not a magnitude of the driving current conforms with a criterion that is associated with target brightness of the pixel unit.
風險溝通在食安管理中之必要性：以狂牛症事件為例
(交通大學科技法律學院（原名稱：交通大學科技法律研究所）, 2017-06-15)
許耀明
;
譚偉恩
;
Yao-Ming Hsu
;
Wei-En Tan
「風險溝通」強調利害關係人之間水平式的對話與資訊交換，其目的是為了使食安管理措施更為周延並符合審議式民主的需求。然而，將風險溝通納入食安管理，會不會對科學專業的判斷或政府管理工作的進行產生妨礙？此問題的背後至少包含了兩個值得細究但一直存有爭論的議題：1.風險溝通是否有助於治理食安問題，以致於具有重要性而必須被重視？2.風險溝通是否僅對消費者有利，但卻不利於食品業者或供應方，甚至會增加政府行政上的成本？本文認為，從風險管理的角度觀之，風險溝通能夠將消費者的真實需求或憂慮融入到食品安全的管理政策中。此種治理機制符合民主政治對於問責性的要求，讓風險承擔者知曉在與其自身利害相關之食安法制中究竟存有什麼風險，以及這些風險可能為自己帶來的利弊得失。當制度上利害關係人皆能獲得充分資訊時，其風險承擔或風險迴避的能力將隨之獲得提升，此結果對於食品市場的交易秩序將具有正面裨益，亦有益於政府食安管理目標之達成。
Detection of ricin by using gold nanoclusters functionalized with chicken egg white proteins as sensing probes
(2017-06-15)
Selvaprakash, Karuppuchamy
;
Chen, Yu-Chie
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應用化學系
;
Department of Applied Chemistry
Ricin produced from the castor oil plant, Ricinus communis, is a well-known toxin. The toxin comprises A and B chains. Ricin A chain can cause toxicity by inhibiting protein synthesis, and ricin B can bind to the galactose ligand on the cell membrane of host cells. Inhalation or ingestion of ricin may even lead to death. Therefore, rapid and convenient sensing methods for detecting ricin in suspicious samples must be developed. In this study, we generated protein encapsulated gold nanoclusters (AuNCs@ew) with bright photoluminescence by using chicken egg white proteins as starting materials to react with aqueous tetrachloroaurate. The generated nanoclusters, which were mainly composed of chicken ovalbumin-encapsulated AuNCs, can recognize ricin B because of the presence of Ga1 beta(1 -> 4)GlcNAc ligands on chicken ovalbumin. The generated conjugates of AuNCs@ew and ricin B were heavy and readily settled down under centrifugation (13,000 rpm, 60 min). Thus, bright spots resulting from the conjugates at the bottom of the sample vials were easily visualized by the naked eye under ultraviolet light illumination. The limit of detection (LOD) was similar to 4.6 mu M. The LOD was reduced to similar to 400 nM when fluorescence spectroscopy was used as the detection tool, while the LOD can be further improved to similar to 7.8 nM when using matrix-assisted laser desorption/ionization mass spectrometry as the detection method. We also demonstrated the feasibility of using the proposed approach to selectively detect ricin B chain in complex samples.
食品標示與WTO/TBT協定合致性之研析
(交通大學科技法律學院（原名稱：交通大學科技法律研究所）, 2017-06-15)
張南薰
;
Nan-Hsun Chang
在一連串的食安風暴後，消費者意識到在商業化及全球化的食品生產過程中，自己所吃的食物與自己的認知可能有一段差距，也開始介意自己所吃的食品，原料為何、成分為何及從何而來。食品標示法規即為一國政府提供其民眾關於食品資訊之重要規範，但食品標示規範同時亦會增加食品製造商及貿易商之成本，而有構成隱藏性貿易障礙之可能性。在WTO 之爭端解決程序中已有多起涉及食品標示法規之TBT 協定之案例。本文希望透過案例之分析，能夠更明確掌握TBT 協定下之若干重要原則之解釋及適用，並進一步瞭解制定食品標示法規時所涉及之國際法上之權利及義務關係。
LED-side-pumped Nd:YAG laser with > 20% optical efficiency and the demonstration of an efficient passively Q-switched LED-pumped solid-state laser
(2017-06-15)
Cho, Chun Yu
;
Pu, Chi Chih
;
Su, Kuan Wei
;
Chen, Yung Fu
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電子物理學系
A LED-array-pumped Nd:YAG laser with optical conversion efficiency up to 20.2% is demonstrated by direct side-pumping without a coupling lens. The 810-nm LED array with a full-width-half-maximum of 30 nm and an area fill factor of 50% is designed to attain high spectral absorption efficiency with a pump density of 151.8 W/cm(2). Furthermore, higher than 45% overall coupling efficiency is achieved by placing the LED array as close as possible to the side of the gain medium for overcoming the large pumped divergence. More importantly, by using the efficient pump scheme, the demonstration of a passively Q-switched LED-pumped laser is successfully realized with a pulsed energy of 1.42 mJ. (C) 2017 Optical Society of America
Compressible 1D photonic crystal nanolasers with wide wavelength tuning
(2017-06-15)
Lu, Tsan-Wen
;
Wu, Chia-Cheng
;
Wang, Chun
;
Lee, Po-Tsung
;
資訊工程學系
We propose and demonstrate a tunable photonic crystal nanolaser consisting of 1D periodic nanorods wrapped in deformable polydimethylsiloxane. In addition to low-threshold and long-term lasing stability, the nanolaser also displays reproducible and reliable wavelength tuning with a large tunability of 7.7 nm under 1% compression. By further associating with stretching, a very wide wavelength-tunable range of 155 nm that almost spans the entire S + C + L telecommunication bands is successfully demonstrated with a single nanolaser device. (C) 2017 Optical Society of America
我國禁止行賄外國公務員法制之探討
(交通大學科技法律學院（原名稱：交通大學科技法律研究所）, 2017-06-15)
黃思翰
;
林志潔
;
Szu-Han Huang
;
Chih-Chieh Lin
近年有關禁止行賄外國公務員之議題已受到國際社會重視，尤其當美國政府對於違反海外反貪腐法（Foreign Corrupt Practices Act, FCPA）之執法地域範圍從歐美擴及於亞洲時，我國企業及科技公司應更加重視企業行賄外國公務員之防制，以降低相關法律風險。然而，過去我國肅貪政策係以公部門貪腐防制為重心。雖然我國於2003 年將行賄外國公務員行為刑罰化，惟從防制跨國賄賂犯罪與提升企業競爭力之角度而言，現行法存有許多疑義尚待釐清，並使得我國企業無妥適之法律制度可資遵循。本文旨在探討我國禁止行賄外國公務員規範與實務之相關問題，除說明有關FCPA 之企業遵法議題外，並嘗試從美國法觀點與實證質性研究分析我國防制行賄外國公務員及企業遵法應有之制度內涵，以及提出立法政策建議，以兼顧打擊跨國行賄與保障企業利益之目的。
有機發光元件及其製法
(2017-06-16)
孟心飛
;
冉曉雯
;
洪勝富
;
張宇帆
;
楊劭鈞
一種有機發光元件，包括：第一電極；平坦層，係形成於該第一電極上；電洞傳輸層，係形成於該平坦層上，使該平坦層夾置於該第一電極和該電洞傳輸層之間，其中，該電洞傳輸層包括具有芴衍生結構之聚合物；發光層，係形成於該電洞傳輸層上，使該電洞傳輸層夾置於該平坦層和該發光層之間，其中，該發光層包括雙主體材料及客發光體；以及第二電極，係形成於該發光層上，使該發光層夾置於該電洞傳輸層和第二電極之間，藉此提升有機發光元件的發光壽命。本發明復提供製造有機發光元件之方法。
具攝影機自動調派功能之3D影像監控系統及其監控方法
(2017-06-16)
黃嘉新
;
梁家銘
;
林奕廷
;
李冠毅
;
吳昆儒
一種3D影像監控系統，運用於監控端電腦並且包括監控目標物網點產生單元、覆蓋矩陣產生單元及權重矩陣產生單元。監控目標物網點產生單元對監控目標物進行切割以獲得複數表面視點；覆蓋矩陣產生單元根據複數攝影機的監控視野與複數表面視點產生覆蓋矩陣；權重矩陣產生單元依據依據覆蓋矩陣判斷各表面視點的被覆蓋機率，並據以產生權重矩陣。3D影像監控系統基於各個攝影機的不同監控視野與複數表面視點的覆蓋關係挑選適合的攝影機，並決定被挑選的攝影機要採用的監控視野。藉此，達到高效率、高覆蓋率、高影像清晰度的即時性攝影機調派工作。
用於無線區域網路中多接取點之合作傳輸系統及其方法
(2017-06-16)
伍紹勳
;
趙禧綠
;
曾俊凱
一種用於無線區域網路中多接取點之合作傳輸系統及其方法，係包括：複數個接取點、分群控制器以及至少一個叢集控制器。該複數個接取點係用於分別服務其服務範圍內之至少一使用者之設備，該分群控制器用於依據該複數個接取點之位置及該服務範圍以分群該複數個接取點，俾將該複數個接取點分群成複數個叢集，該至少一個叢集控制器用於控制其所管轄之叢集內所有接取點之間的合作式同步下行傳輸，且叢集之間在交集時，係採用干擾抑制機制，透過交換使用者通道資訊，以消除位於不同叢集交集區之使用者之設備所產生之干擾。本發明透過合作式通訊技術以及干擾抑制機制，將可避免無線區域網路中多個接取點之間因重疊基本服務區所產生之干擾。
畫素補償裝置、具有電流補償功能的顯示器
(2017-06-16)
戴亞翔
;
林玄用
;
張君毅
一種畫素補償裝置包含一個設定開關、一個畫素電路及一個補償電路。設定開關具有一接收一周期信號的第一端及一第二端，且受控制使該設定開關於導通與不導間切換，當導通時，該周期信號傳送到該第二端。畫素電路電連接該設定開關的第二端，當該設定開關導通時，該畫素電路接收來自該設定開關的該周期信號，且根據該周期信號產生一驅動電流。補償電路電連接該畫素電路與該設定開關的控制端，用來接收來自該畫素電路的該驅動電流，該補償電路判斷該驅動電流的大小是否符合一預設值，以決定是否將該設定開關切換成不導通，該預設值相關於一畫素亮度值。