Browsing by Issue Date, starting with "2017-07-16"

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滴點式複合藥物凝膠及其製備方法
(2017-07-16)
劉典謨
;
王依齡
本發明提供一種滴點式複合藥物凝膠，包含複數個幾丁聚醣微胞、鹼性結構安定劑以連接複數個幾丁聚醣微胞、第一藥物於複數個幾丁聚醣微胞之內、以及第二藥物於複數個幾丁聚醣微胞之外。
用於控制行走輔具的方法
(2017-07-16)
宋開泰
;
吳尚陽
;
江信毅
一種用於控制行走輔具的方法，利用雷射掃描儀來偵測使用者的步態資訊，並利用力矩感測器來偵測使用者的施力方向，作為行走輔具運動控制的輸入資訊，進而運用順應性控制來達成行動輔助的功效。其中以使用者的步態資訊調整行走輔具的移動速度，而以力矩感測資訊調整行走輔具的行進方向，能產生行走輔具所需的被動行為，有效達成助行之功能。此外，本發明還提供一種行走輔具的自主避障機制，藉由結合該自主避障機制與上述的順應性控制，能讓行走輔具在複雜的環境中避免碰撞障礙物，提供使用者更安全的操作。
光學量測系統及其濃度感測裝置
(2017-07-16)
孟心飛
;
冉曉雯
;
鄭宏志
;
蔡美娟
;
周哲宇
一種光學量測系統，其適於量測待測物的濃度。光學量測系統包括濃度感測裝置、光源以及光偵測器。濃度感測裝置包括濃度偵測膜、入光波導以及出光波導。入光波導以及出光波導分別耦接於濃度偵測膜。濃度感測裝置由入光波導的入光端接收來自光源的第一光束，且濃度感測裝置由出光波導的出光端輸出第二光束至光偵測器。在濃度偵測膜與待測物反應後，第二光束的光強度指示待測物的濃度。另提供光學量測系統及其濃度感測裝置。
Risk of gestational hypertension-preeclampsia in women with preceding endometriosis: A nationwide population-based study
(2017-07-17)
Pan, Mei-Lien
;
Chen, Li-Ru
;
Tsao, Hsiao-Mei
;
Chen, Kuo-Hu
;
機械工程學系
Objective To investigate the association between preceding endometriosis and gestational hypertension-preeclampsia (GH-PE). Methods In this nationwide population-based longitudinal study, data from 1998-2012 Taiwan National Health Insurance Research Database were used. We used ICD9-CM codes 617.X and 642.X respectively for the diagnoses of endometriosis and GH-PE, which were further confirmed by examining medical records of surgeries, blood pressure and urine protein to ensure the accuracy of the diagnoses. The study excluded women diagnosed with endometriosis at < 15 or > 45 years of age, chronic hypertension, and GH-PE prior to endometriosis. Each pregnant woman with a prior diagnosis of endometriosis was matched to 4 pregnant women without endometriosis by age. Logistic regression analysis was used to calculate odds ratios (ORs) for the risk of GH-PE with adjustment for age, occupation, urbanization, economic status and comorbidities. Results Among 6,300 women with a prior endometriosis diagnosis who were retrieved from a population of 1,000,000 residents, 2,578 (40.92%) had subsequent pregnancies that were eligible for further analysis and were compared with 10,312 pregnant women without previous endometriosis. GH-PE occurred more in women with prior endometriosis as compared to those without endometriosis (3.88% vs. 1.63%, p<0.0001). Further analysis revealed prior endometriosis was associated with GH-PE (adjusted OR = 2.27; 95% CI: 1.76-2.93). For danazol-treated and non-danazol-treated subgroups, the incidences of GH-PE were 3.13% (15/480) and 4.05% (85/2,098), respectively. Although the risk for subsequent GH-PE was lower (adjusted OR = 1.49; 95% CI: 0.86-2.56) after receiving danazol treatment than average (adjusted OR = 2.27; 95% CI:1.76-2.93) for women with preceding endometriosis, the reduction of risk was not statistically remarkable for danazol-treated (adjusted OR = 1.49) vs. non-danazol-treated (adjusted OR = 2.48) subgroups (p heterogeneity = 0.12). Conclusions Preceding endometriosis is an independent and significant risk factor for the occurrence of GH-PE.
Characterization of nitride hole lateral transport in a charge trap flash memory by using a random telegraph signal method
(2017-07-17)
Liu, Yu-Heng
;
Jiang, Cheng-Min
;
Lin, Hsiao-Yi
;
Wang, Tahui
;
Tsai, Wen-Jer
We use a random telegraph signal method to investigate nitride trapped hole lateral transport in a charge trap flash memory. The concept of this method is to utilize an interface oxide trap and its associated random telegraph signal as an internal probe to detect a local channel potential change resulting from nitride charge lateral movement. We apply different voltages to the drain of a memory cell and vary a bake temperature in retention to study the electric field and temperature dependence of hole lateral movement in a nitride. Thermal energy absorption by trapped holes in lateral transport is characterized. Mechanisms of hole lateral transport in retention are investigated. From the measured and modeled results, we find that thermally assisted trap-to-band tunneling is a major trapped hole emission mechanism in nitride hole lateral transport. Published by AIP Publishing.
Bulk vs. Surface Structure of 3d Metal Impurities in Topological Insulator Bi2Te3
(2017-07-18)
Leedahl, B.
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Boukhvalov, D. W.
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Kurmaev, E. Z.
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Kukharenko, A.
;
Zhidkov, I. S.
Topological insulators have become one of the most prominent research topics in materials science in recent years. Specifically, Bi2Te3 is one of the most promising for technological applications due to its conductive surface states and insulating bulk properties. Herein, we contrast the bulk and surface structural environments of dopant ions Cr, Mn, Fe, Co, Ni, and Cu in Bi2Te3 thin films in order to further elucidate this compound. Our measurements show the preferred oxidation state and surrounding crystal environment of each 3d-metal atomic species, and how they are incorporated into Bi2Te3. We show that in each case there is a unique interplay between structural environments, and that it is highly dependant on the dopant atom. Mn impurities in Bi2Te3 purely substitute into Bi sites in a 2+ oxidation state. Cr atoms seem only to reside on the surface and are effectively not able to be absorbed into the bulk. Whereas for Co and Ni, an array of substitutional, interstitial, and metallic configurations occur. Considering the relatively heavy Cu atoms, metallic clusters are highly favourable. The situation with Fe is even more complex, displaying a mix of oxidation states that differ greatly between the surface and bulk environments.
Tilted Two-Dimensional Array Multifocus Confocal Raman Microspectroscopy
(2017-07-18)
Yabumoto, Sohshi
;
Hamaguchi, Hiro-o
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應用化學系
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應用化學系分子科學碩博班
;
Department of Applied Chemistry
A simple and efficient two-dimensional multi focus confocal Raman microspectroscopy featuring the tilted array, technique is demonstrated. Raman scattering from a 4 X 4 square foci array passing through a 4 X 4 confocal pinhole array is tilted with a periscope. The tilted array of Raman scattering signals is dispersed by an imaging spectrograph onto a CCD detector, giving 16 independent Raman spectra formed as 16 bands with different heights on the sensor. Use of a state-of-theart imaging spectrograph enables high-precision wavenumber duplicability of the 16 spectra. This high duplicability makes the simultaneously obtained spectra endurable for multivariate spectral analyses, which is demonstrated by a singular value decomposition analysis for Raman spectra of liquid indene. Although the present implementation attains only 16 measurement points, the number of points can be extended to larger than 100 without any technical leaps. Limit of patallelization depends on the interval of measurement points as Well as the performance of the optical system. Criteria for finding the maximum feasible number are discussed.
Spectroscopic Characterization of the Reaction Products between the Criegee Intermediate CH2OO and HCl
(2017-07-19)
Cabezas, Carlos
;
Endo, Yasuki
;
應用化學系
;
Department of Applied Chemistry
Pulsed Fourier-transform microwave experiments have been performed to probe the products resulting from the reaction between HCl and the simplest Criegee intermediate, CH2OO, where the reaction is considered to be important in atmospheric chemistry. The experimentally determined rotational parameters interpreted with the help of quantum chemical calculations support the identification of chloro-methyl hydroperoxide molecule as the primary product of this reaction.
Surface Layering and Supersaturation for Top-Down Nanostructural Development during Spin Coating of Polymer/Fullerene Thin Films
(2017-07-19)
Wu, Wei-Ru
;
Su, Chun-Jen
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Chuang, Wei-Tsung
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Huang, Yen-Chih
;
Yang, Po-Wei
This study provides new evidence on a long postulated mechanism of phase separation in a polymer/fullerene mixture during spin coating for controlled nanodomains of oriented crystallization and heterojunctions that favor applications in polymer solar cells (PSCs). The simultaneous nanoscale phase separation and crystallization during spin coating of the mixture are traced using in situ grazing-incidence small-and wide-angle X-ray scattering. Combined with the complimentary results from time-resolved optical reflectance spectroscopy, transient stratification of the liquid film during the transition from the flow-to evaporation-dominated stage of spin coating is disclosed; the vertical liquid-liquid phase separation incubates a supersaturated skin layer where fullerene aggregation and polymer crystallization occur and develop concomitantly. Shortly after the transition, the near-surface structural development is largely pinned, leaving the solvent-rich bottom layer to diminish via solvent diffusion and evaporation through the thickened skin layer that finally condenses into the spin-coated film upon solvent depletion. The shear-enhanced surface layering and supersaturation for the surface-down nanostructural development are unexpected in all the existing structural models for PSCs. The mechanistic understanding of coupled vertical phase separation and local nanosegregation provides new insights and alternative strategy to the morphology control of spin-cast PSC active layers in particular and various solution-processed polymeric films in general.
NETWORK COMMUNICATION SYSTEM, SOFTWARE-DEFINED NETWORK CONTROLLER AND ROUTING METHOD THEREOF
(2017-07-20)
Ying-Dar Lin
;
Cheng-Ying Wu
;
Po-Ching Lin
;
Yuan-Cheng Lai
A network communication system, a software-defined network controller and a routing method thereof are provided. The routing method is adapted to the software-defined network controller. The routing method includes the following steps: determining a first root switch corresponding to at least one first service cluster according to service chaining information, wherein each of the at least one first service cluster includes at least one service node for providing a first service; determining first routing path information for routing a packet flow from a first target switch to the first root switch; and configuring first group entry information for the first root switch according to cluster information of the at least one first service cluster, wherein the first group entry information is for performing a first routing path selection of the packet flow corresponding to the first service by the first root switch.
Silver nanoparticles embedded boron-doped reduced graphene oxide as anode material for high performance lithium ion battery
(2017-07-20)
Bindumadhavan, Kartick
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Chang, Pei-Yi
;
Doong, Ruey-an
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環境工程研究所
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Institute of Environmental Engineering
Lithium ion batteries (LIBs) are important energy generation and storage devices and the development of anode materials can improve the electrochemical performance of LIBs. Herein, we report the fabrication of Ag nanoparticles embedded boron-doped reduced graphene oxide (Ag/B-rGO) with the addition of 10-30 wt% boric acid as anode materials for high performance LIB application. The combination of Ag nanoparticles with B-doped rGO enhances the reactivity of nanocomposites toward Li+ ions intercalation. The Ag/B-rGO nanocomposites with the addition of 30 wt% boric acid (Ag/B-rGO-30) exhibits significantly improved rate capability. The reversible capacity of 1484 mAh g(-1) at 50 mAg(-1) is initially observed and can retain at 430 mAh g(-1) when the current density increases to 1000 mAg(-1). In addition, the Ag/B-rGO exhibits the stable capacity of 540 mAh g(-1) at 100 mAg(-1) after 100 cycles of lithiation/delithiation process. The presence of doped boron improves the electron density and increases the defect sites, resulting in the acceleration of electron transfer rate through the graphitic network. In addition, the embedded Ag nanoparticles with diameters of 10-15 nm over 2-3 layered B-rGO decrease the internal resistance of Ag/B-rGO nanocomposites as well as improve the conductively nano-dimensional contacts for electron transport. Results obtained in this study clearly demonstrate the role of heteroatoms in the enhancement of electrochemical performance of lithiation capacity and can open a new route to fabricate metal-decorated rGO-based nanomaterials for high performance energy storage devices. (c) 2017 Elsevier Ltd. All rights reserved.
交大e-News第236期-交大CGI圍棋程式擊敗紅面棋王
(2017-07-20)
國立交通大學秘書室
;
Secretariat
Inverted planar solar cells based on perovskite/graphene oxide hybrid composites
(2017-07-21)
Chung, Chih-Chun
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Narra, Sudhakar
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Jokar, Efat
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Wu, Hui-Ping
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Diau, Eric Wei-Guang
Mixing graphene oxide (GO) with CH3NH3PbI3 (PSK) in varied proportions (0.025, 0.05 and 0.075 mg mL(-1)) and using GO nanosheets as a p-type electrode for devices with a layer-by-layer thin-film configuration ITO/GO/PSK: GO/PCBM/Ag produced hybrid composite perovskite solar cells. The efficiency of power conversion (PCE) of the device prepared with GO in PSK solution (0.05 mg mL(-1)) attained 15.2%, which is greater than that of a conventional planar heterojunction device (PCE 12.3%) fabricated using pristine PSK. In the homogeneous PSK: GO active layers, PSK acted as a hole donor and GO as a hole acceptor. The optimum GO concentration (0.05 mg mL(-1)) increased the charge mobility (investigated using Hall effect measurements), enhanced the charge separation (investigated using photoluminescence decays) and retarded the charge recombination (investigated using electrochemical impedance spectra), consistent with the trend of corresponding device performances. Our results thus indicate that the hybrid PSK: GO layer increased the interfacial contact between the donor and acceptor of holes to balance the charge mobility and improved the photovoltaic performance with excellent reproducibility and stability.
Speckle reduction using deformable mirrors with diffusers in a laser pico-projector
(2017-07-24)
Chen, Hsuan-An
;
Pan, Jui-Wen
;
Yang, Zu-Po
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光電系統研究所
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影像與生醫光電研究所
We propose a design for speckle reduction in a laser pico-projector adopting diffusers and deformable mirrors. This research focuses on speckle noise suppression by changing the angle of divergence of the diffuser. Moreover, the speckle contrast value can be further reduced by the addition of a deformable mirror. The speckle reduction ability obtained using diffusers with different divergence angles is compared. Three types of diffuser designs are compared in the experiments. For Type 1 which uses a circular symmetric diffuser the speckle contrast value can be decreased to 0.0264. For Type 2, the speckle contrast value can be reduced to 0.0267 because of the inclusion of an elliptical distribution diffuser. With Type 3 which includes a combination of the circular distribution diffuser and elliptical distribution diffuser, the speckle contrast value can be reduced to 0.0236. For all three types, the speckle contrast value is lower than 0.05. Under this speckle value, the speckle phenomenon is invisible to the human eye. (C)2017 Optical Society of America
Magnetic hyperthermia enhance the treatment efficacy of peri-implant osteomyelitis
(2017-07-25)
Fang, Chih-Hsiang
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Tsai, Pei-I
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Huang, Shu-Wei
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Sun, Jui-Sheng
;
Chang, Jenny Zwei-Chieng
Background: When bacteria colony persist within a biofilm, suitable drugs are not yet available for the eradication of biofilm-producing bacteria. The aim of this study is to study the effect of magnetic nano-particles-induced hyperthermia on destroying biofilm and promoting bactericidal effects of antibiotics in the treatment of osteomyelitis. Methods: Sixty 12-weeks-old male Wistar rats were used. A metallic 18G needle was implanted into the bone marrow cavity of distal femur after the injection of Methicillin-sensitive Staphylococcus aureus (MSSA). All animals were divided into 5 different treatment modalities. The microbiological evaluation, scanning electron microscope examination, radiographic examination and then micro-CT evaluation of peri-implant bone resorption were analyzed. Results: The pathomorphological characteristics of biofilm formation were completed after 40-days induction of osteomyelitis. The inserted implants can be heated upto 75 degrees C by magnetic heating without any significant thermal damage on the surrounding tissue. We also demonstrated that systemic administration of vancomycin [VC (i.m.)] could not eradicate the bacteria; but, local administration of vancomycin into the femoral canal and the presence of magnetic nanoparticles hyperthermia did enhance the eradication of bacteria in a biofilm-based colony. In these two groups, the percent bone volume (BV/TV: %) was significantly higher than that of the positive control. Conclusions: For the treatment of chronic osteomyelitis, we developed a new modality to improve antibiotic efficacy; the protection effect of biofilms on bacteria could be destroyed by magnetic nanoparticles-induced hyperthermia and therapeutic effect of systemic antibiotics could be enhanced.
Quantum control of atomic two-photon ionization by ultrashort light pulse effect
(2017-07-25)
Lee, Han Chieh
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Da Jheng, Shih
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Jiang, Tsin Fu
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物理研究所
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Institute of Physics
We demonstrate that the two-photon photoelectron spectrum can be manipulated by an ultra-short light pulse. We decompose a short pulse into a linear superposition of Fourier modes. The two-photon transition amplitude becomes a summation of all pathways. The contribution of each pathway was accurately calculated by using a second-order variational method. By properly choosing the carrier frequency and pulse duration according to the calculated two-photon absorption factor versus the absorbed first photon energy, the photoelectron spectrum can become single-or double-peaked. We use the hydrogen atom as a model and study both cases of linearly and circularly polarized light pulse.
Bianchi type I anisotropic power-law solutions for the Galileon models
(2017-07-25)
Do, Tuan Q.
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Kao, W. F.
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物理研究所
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Institute of Physics
We will study the cosmological solutions of a class of Galileon models. A special class of the Bianchi type I power-law solutions will be presented in this paper. We will show that these Bianchi type I power-law solutions are stable during the inflationary phase. In addition, we will also show that the presence of a phantom field induces at least an unstable mode for the perturbation equation and destabilizes the power-law solutions.
Handedness of Twisted Lamella in Banded Spherulite of Chiral Polylactides and Their Blends
(2017-07-25)
Wang, Hsiao-Fang
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Chiang, Chen-Hung
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Hsu, Wen-Chun
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Wen, Tao
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Chuang, Wei-Tsung
Banded spherulite resulting from lamellar twisting due to the imbalanced stresses at opposite fold surfaces can be formed by isothermal crystallization of chiral polylactide and its blends with poly(ethylene glycol) (PEG). Using a polarized light microscope, the handedness of the twisted lamella in banded spherulite is determined. With the same growth axis along the radial direction as evidenced by wide-angle X-ray diffraction (WAXD) for isothermally crystallized samples at different temperatures, the twisted lamellae of chiral polylactides (poly(L-lactide) (PLLA) and poly(D-lactide) (PDLA)) display opposite handedness. The split-type Cotton effect on the Co=O stretching motion of vibrational circular dichroism (VCD) spectra helps determine the helix handedness (i.e., conformational chirality). The results indicate that the conformational chirality can be defined by the molecular chirality through intramolecular chiral interactions. Moreover, the preferred sense of the lamellar twist in the banded spherulite corresponds to the twisting direction identified by the C-O-C vibration motion of VCD spectra, reflecting the role of intermolecular chiral interactions in the packing of polylactide helices. Similar results are obtained in the blends of chiral polylactides and poly(ethylene glycol) (PEG, a polymer compatible with polylactide), indicating that the impact of chirality is intrinsic irrespective of the specific crystallization conditions. In contrast to the chiral polylactides, the spectrum of the crystalline stereocomplex that associates PLLA and PDLA shows VCD silence. The spectroscopic results are in line with the morphological observations. No banded spherulites are observed in the stereocomplex crystallites due to the symmetric packing of mirror L and D-chain conformations in the fold surfaces and the crystallites core.
Effect of crosslinking agents on the dispersive behaviour of polymer particles in seed swelling polymerisation
(2017-07-25)
Kao, Yu-Chen
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Whang, Wha-Tzong
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Chen, Yi-Chun
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Chen, Kai-Chi
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材料科學與工程學系
This study focused on the effect of crosslinker structure between PMMA on the dispersity of crosslinked particles in seed swelling polymerisation. We used five different crosslinking agents in an assessment of the dispersity of crosslinking monodisperse particles using PMMA seed particles in seed swelling polymerisation. These results show that the structure of the crosslinking agent affects the dispersity during the swelling stage. According to the solubility parameter theory of computation, the departure of similar solubility parameter causes the swollen particles to segregate into more dispersity. (C) 2017 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.
Cobalt-catalyzed regioselective [3+2] annulation of ortho-formyl and acetyl substituted phenylboronic acids with alkynes
(2017-07-26)
Ueda, Mitsuhiro
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Ueno, Tamami
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Suyama, Yuki
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Ryu, Ilhyong
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應用化學系
Treatment of alkynes with ortho-formyl and acetyl phenylboronic acids in the presence of a cobalt catalyst resulted in the formation of 2,3-disubstituted indenols in good yields. When aryl silyl alkynes were used, 2-aryl-3-silyl indenols were obtained regioselectively in good yields. (C) 2017 Elsevier Ltd. All rights reserved.