Browsing by Issue Date, starting with "2018-05-18"

Now showing 1 - 20 of 10696

Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells
(2018-05-18)
Hsieh, Fang-Chi
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Lu, Yu-Fen
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Liau, Ian
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Chen, Chien-Chang
;
Cheng, Chao-Min
Sarcomeric signaling complexes are important to sustain proper sarcomere structure and function, however, the mechanisms underlying these processes are not fully elucidated. In a gene trap experiment, we found that vascular cell adhesion protein 1 isoform X2 (VCAP1X2) mutant embryos displayed a dilated cardiomyopathy phenotype, including reduced cardiac contractility, enlarged ventricular chamber and thinned ventricular compact layer. Cardiomyocyte and epicardial cell proliferation was decreased in the mutant heart ventricle, as was the expression of pAKT and pERK. Contractile dysfunction in the mutant was caused by sarcomeric disorganization, including sparse myofilament, blurred Z-disc, and decreased gene expression for sarcomere modulators (smyd1b, mypn and fhl2 alpha), sarcomeric proteins (myh6, myh7, vmhcl and tnnt2 alpha) and calcium regulators (ryr2b and slc8a1 alpha). Treatment of PI3K activator restored Z-disc alignment while injection of smyd1b mRNA restored Z-disc alignment, contractile function and cardiomyocyte proliferation in ventricles of VCAP1X2 mutant embryos. Furthermore, injection of VCAP1X2 variant mRNA rescued all phenotypes, so long as two cytosolic tyrosines were left intact. Our results reveal two tyrosine residues located in the VCAP1X2 cytoplasmic domain are essential to regulate cardiac contractility and the proliferation of ventricular cardiomyocytes and epicardial cells through modulating pAKT and pERK expression levels.
Single-fabrication-step Ge nanosphere/SiO2/SiGe heterostructures: a key enabler for realizing Ge MOS devices
(2018-05-18)
Liao, P. H.
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Peng, K. P.
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Lin, H. C.
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George, T.
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Li, P. W.
We report channel and strain engineering of self-organized, gate-stacking heterostructures comprising Ge-nanosphere gate/SiO2/SiGe-channels. An exquisitely-controlled dynamic balance between the concentrations of oxygen, Si, and Ge interstitials was effectively exploited to simultaneously create these heterostructures in a single oxidation step. Process-controlled tunability of the channel length (5-95 nm diameters for the Ge-nanospheres), gate oxide thickness (2.5-4.8 nm), as well as crystal orientation, chemical composition and strain engineering of the SiGe-channel was achieved. Single-crystalline (100) Si1-xGex shells with Ge content as high as x = 0.85 and with a compressive strain of 3%, as well as (110) Si1-xGex shells with Ge content of x = 0.35 and corresponding compressive strain of 1.5% were achieved. For each crystal orientation, our high Ge-content, highly-stressed SiGe shells feature a high degree of crystallinity and thus, provide a core 'building block' required for the fabrication of Ge-based MOS devices.
彩虹起義　平權公投
(2018-05-20)
嚴銘浩
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蔡亞融
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Department of Communication and Technology
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傳播與科技學系
【彩虹路上】專題

彩虹起義台灣行動大隊第一次公投說明會發起人中苗博雅、法律白話文王鼎棫之影音專訪。
失智照護新趨勢　為高齡化領航
(2018-05-20)
蕭巧昱
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Department of Communication and Technology
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傳播與科技學系
【遺忘芳華　丟失在回憶邊境的住民】專題

高齡化已是社會中不可擋的趨勢，伴隨著失智症盛行率增加的問題，本圖標將帶您一探失智照護的發展現況。
僑生大學生活　三大挑戰
(2018-05-20)
關子茵
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Department of Communication and Technology
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傳播與科技學系
【僑生面面觀】專題

僑生在大學的生活的如何？又會遇到什麼問題和抉擇呢？有些問題，不只僑生，就連本地學生也會遇到，該如何解決呢？
從業務員變玩具醫生──馮寶安
(2018-05-20)
楊巧柔
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Department of Communication and Technology
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傳播與科技學系
【二手玩具物流】專題

玩具也有醫生？玩具醫生馮寶安從圖書業務變為玩具救星！
林端容　突破創業者的窘境
(2018-05-20)
王貞懿
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Department of Communication and Technology
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傳播與科技學系
【破繭而出的年輕世代】專題

青年創業潮持續發燒，許多年輕人想自行創業，卻在許多地方遇到阻礙。創辦Changee及Simpany的林端容，根據創業者的需求提供相對應的協助。
彩虹辭典
(2018-05-20)
郭庭芸
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Department of Communication and Technology
;
傳播與科技學系
【彩虹路上】專題

以互動網頁形式，收錄常見之性別議題相關名詞，用活潑有趣的方式協助讀者熟悉詞意，能夠更加輕鬆地閱讀本專題。
彩虹路上
(2018-05-20)
嚴銘浩
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簡文怡
;
戴葦婷
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蔡亞融
;
徐仟妤
多元性別的議題越來越受關注，台灣更有可能成為亞洲第一個合法讓同性戀結婚的地方，但社會上又是不是每一個人都了解當中的所有。因此我們就希望以這一次的專題報導去解決大眾對這個主題的困惑。
各國重機法規小教室
(2018-05-20)
蔡翔宇
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Department of Communication and Technology
;
傳播與科技學系
【被壓抑的野獸　重機族群的困境】專題

本篇圖表帶您簡單地了解各國關於重機的法律有哪些不同。
總編輯的話
(2018-05-20)
馮瑜庭
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Department of Communication and Technology
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傳播與科技學系
本期為喀報290期，稿件共計12篇，類型多元並出現兩則以廣播為媒材的報導。本期專題「彩虹路上」採用豐富媒材帶領讀者深入了解同志議題，並點出同志在台灣面臨的現況。
從卡通看見多元性別教育
(2018-05-20)
徐仟妤
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Department of Communication and Technology
;
傳播與科技學系
【彩虹路上】專題

觀察卡通中的多元性別題材，並探索在性別平等教育的可能性。
日常對話　對你講出心內話
(2018-05-20)
簡文怡
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Department of Communication and Technology
;
傳播與科技學系
【彩虹路上】專題

有個T媽媽是怎樣的感受？當共享傷痛，要如何練習對身邊的人說愛？看黃惠偵用紀錄片與母親超渡黑暗、相依扶持。
用心和毅力　女力征服太空
(2018-05-20)
葉宜瑩
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Department of Communication and Technology
;
傳播與科技學系
【台灣太空探索之旅】專題

身為少數在台灣太空領域工作的女性，朱崇惠如何成為台灣福衛系列計畫中首位女性計畫總主持人？
這些年台灣如何看待多元性別？
(2018-05-20)
戴葦婷
;
Department of Communication and Technology
;
傳播與科技學系
【彩虹路上】專題

從1996年的亞洲首個公開的同志婚禮，到走入校園、職場的性別工作平等法及性別平等教育法，再到2017年的同婚釋憲，乍看之下同性權益爭取十分順利，然而一路上其實走得顛簸。
到底台灣經歷了哪些事才蛻變成即將成為亞洲第一個同性婚姻合法化國家？一起點開動態圖表瞧瞧吧！
林聖修　獨自前行的出版之路
(2018-05-20)
戴淨妍
;
Department of Communication and Technology
;
傳播與科技學系
【紙本書與電子書】專題

專訪啟明出版社社長林聖修，了解他是如何闖出屬於自己的一片天。
交大e-News第255期-校長講座：毛治國教授談管理
(2018-05-21)
國立交通大學秘書室
;
Secretariat
The appropriateness of Bland-Altman's approximate confidence intervals for limits of agreement
(2018-05-22)
Shieh, Gwowen
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管理科學系
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Department of Management Science
Background: Percentiles are widely used as reference limits for determining the relative magnitude and substantial importance of quantitative measurements. An important application is the advocated Bland-Altman limits of agreement. Methods: To contribute to the data analysis and design planning of reference limit or percentile research, the purpose of this paper is twofold. The first is to clarify the statistical features of interval estimation procedures for normal percentiles. The second goal is to provide sample size procedures for precise interval estimation of normal percentiles. Results: The delineation demonstrates the theoretical connections between different pivotal quantities for obtaining exact confidence intervals. Moreover, the seemingly accurate approximate methods with equidistant from the principal estimators are shown to have undesirable confidence limits. It is found that the optimal sample size has a minimum for median or mean, and increases as the percentile approaches the extremes. Conclusions: The exact interval procedure should be used in preference to the approximate methods. Computer algorithms are presented to implement the suggested interval precision and sample size calculations for planning percentile research.
Compact composite noise-reduction LNA for UWB WPAN and WBAN applications
(2018-05-23)
Lin, Chun-Yi
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Liang, Ching-Piao
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Tarng, Jenn-Hwan
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Chung, Shyh-Jong
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電信工程研究所
An ultra-wideband (UWB) low-noise amplifier (LNA) implemented using 180nm complementary metal-oxide-semiconductor technology is presented for wireless personal area network (WPAN) and wireless body area network (WBAN). Increasing the resistance of the substrate resistor R-B reduces the noise factor. When additional substrate resistors and a composite feedback topology are employed, the proposed LNA can achieve both a 1.4dB reduction of the noise figure (NF) and a 4dB enhancement in power gain (PG). Over the operating frequency range from 3.1 to 4.8GHz, the LNA achieves a maximum PG of 14.5dB, a minimum NF of 1.5dB, and an input return loss of <10dB. The measured current consumption is 3mA with a 1.5V supply voltage. The active chip area is 0.008mm(2). The proposed 3.1-4.8GHz LNA has a superior NF, smaller active area, and the lowest dc power consumption compared with devices reported in the literature.
Deep-Ultraviolet Hyperbolic Metacavity Laser
(2018-05-24)
Shen, Kun-Ching
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Ku, Chen-Ta
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Hsieh, Chiieh
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Kuo, Hao-Chung
;
Cheng, Yuh-Jen
Given the high demand for miniaturized optoelectronic circuits, plasmonic devices with the capability of generating coherent radiation at deep subwavelength scales have attracted great interest for diverse applications such as nanoantennas, single photon sources, and nanosensors. However, the design of such lasing devices remains a challenging issue because of the long structure requirements for producing strong radiation feedback. Here, a plasmonic laser made by using a nanoscale hyperbolic metamaterial cube, called hyperbolic metacavity, on a multiple quantum-well (MQW), deep-ultraviolet emitter is presented. The specifically designed metacavity merges plasmon resonant modes within the cube and provides a unique resonant radiation feedback to the MQW. This unique plasmon field allows the dipoles of the MQW with various orientations into radiative emission, achieving enhancement of spontaneous emission rate by a factor of 33 and of quantum efficiency by a factor of 2.5, which is beneficial for coherent laser action. The hyperbolic metacavity laser shows a clear clamping of spontaneous emission above the threshold, which demonstrates a near complete radiation coupling of the MQW with the metacavity. This approach shown here can greatly simplify the requirements of plasmonic nanolaser with a long plasmonic structure, and the metacavity effect can be extended to many other material systems.