Browsing by Issue Date, starting with "2018-11-26"

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eDRAM: Effective early disease risk assessment with matrix factorization on a large-scale medical database: A case study on rheumatoid arthritis
(2018-11-26)
Chin, Chu-Yu
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Hsieh, Sun-Yuan
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Tseng, Vincent S.
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資訊科學與工程研究所
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Institute of Computer Science and Engineering
Recently, a number of analytical approaches for probing medical databases have been developed to assist in disease risk assessment and to determine the association of a clinical condition with others, so that better and intelligent healthcare can be provided. The early assessment of disease risk is an emerging topic in medical informatics. If diseases are detected at an early stage, prognosis can be improved and medical resources can be used more efficiently. For example, if rheumatoid arthritis (RA) is detected at an early stage, appropriate medications can be used to prevent bone deterioration. In early disease risk assessment, finding important risk factors from large-scale medical databases and performing individual disease risk assessment have been challenging tasks. A number of recent studies have considered risk factor analysis approaches, such as association rule mining, sequential rule mining, regression, and expert advice. In this study, to improve disease risk assessment, machine learning and matrix factorization techniques were integrated to discover important and implicit risk factors. A novel framework is proposed that can effectively assess early disease risks, and RA is used as a case study. This framework comprises three main stages: data preprocessing, risk factor optimization, and early disease risk assessment. This is the first study integrating matrix factorization and machine learning for disease risk assessment that is applied to a nation-wide and longitudinal medical diagnostic database. In the experimental evaluations, a cohort established from a large-scale medical database was used that included 1007 RA-diagnosed patients and 921,192 control patients examined over a nine-year follow-up period (2000-2008). The evaluation results demonstrate that the proposed approach is more efficient and stable for disease risk assessment than state-of-the-art methods.
Generating high-power asymmetrical Laguerre-Gaussian modes and exploring topological charges distribution
(2018-11-26)
Hsieh, Y. H.
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Lai, Y. H.
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Hsieh, M. X.
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Huang, K. F.
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Chen, Y. F.
We employ an off-axis pumped Nd:YVO4 laser and control the reflectance of output coupler to directly generate asymmetrical Hermite-Gaussian (HG) modes with various transverse orders. By using an astigmatic mode converter, the generated asymmetrical HG modes are straightforwardly transformed into asymmetrical Laguerre-Gaussian (LG) modes with a crescent-like shape. The average output power of all the crescent-shaped LG modes can exceed 1W at the pump power of 4W. Furthermore, experimental results are theoretically verified by resonant modes derived from the inhomogeneous Helmholtz equation with the localized source distribution. Theoretical resonant modes are also used to explore the dependence of the phase structures of LG modes on the system loss. As the loss increases, it is found that the singularities at the origin will be rearranged and new singularities are formed in the outside region with average orbital angular momentum remaining unchanged. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
Solid-state emitter embedded in a microcavity under intense excitation: A variational master-equation approach
(2018-11-26)
Gomez-Sanchez, Oscar J.
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Ramirez, Hanz Y.
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電子物理學系
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Department of Electrophysics
In this work, dissipative effects from a phonon bath on the resonance fluorescence of a solid-state two-level system embedded in a high-quality semiconductor microcavity and driven by an intense laser are investigated. Within the density operator formalism, we derive a variational master equation valid for broader ranges of temperatures, pumping rates, and radiation-matter couplings than previous studies. From the obtained master equation, fluorescence spectra for various thermal and exciting conditions are numerically calculated and compared to those computed from weak coupling and polaronic master equations, respectively. Our results evidence the breakdown of those rougher approaches under increased temperature and strong pumping.
From Block Copolymer Nanotubes to Nanospheres: Nonsolvent-Induced Morphology Transformation Using Porous Templates
(2018-11-27)
Chang, Chun-Wei
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Tu, Yi-Hsuan
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Luo, Ke-Hsuan
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Chen, Jiun-Tai
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交大名義發表
Block copolymer nanostructures have attracted great attention because of the wide range of applications such as sensors and drug delivery. The fabrication of block copolymer nanostructures with controlled morphologies and sizes, however, is still challenging. Here, we study the fabrication of nanotubes and nanospheres of polystyrene-block-polybutadiene (PS-b-PBD) using anodic aluminum oxide (AAO) templates. When PS-b-PBD solutions in N-methyl-2-pyrrolidone are introduced into the nanopores of the AAO templates applying the traditional solution wetting method, PS-b-PBD nanotubes can be obtained. When PS-b-PBD solutions in the nanopores are in contact with a nonsolvent, acetic acid, PS-b-PBD nanospheres are formed. Two possible mechanisms are proposed to discuss the formation of the nonsolvent-driven morphology transformation, including the Rayleigh-instability-type transformation mechanism and the nucleation and growth mechanism. The effect of the polymer concentrations on the internal morphologies of the PS-b-PBD nanostructures is discussed; at higher concentrations, PS-b-PBD nanocapsules can also be prepared. Furthermore, core-shell PS-b-PBD/polymethylmethacrylate nanospheres can be fabricated using this strategy with polymer blend solutions. This work not only demonstrates a simple strategy to control the morphologies of block copolymer nanostructures but also deepens the understanding of the interactions between polymer solutions and solvents.
Infrared spectra of the 1,1-dimethylallyl and 1,2-dimethylallyl radicals isolated in solid para-hydrogen
(2018-11-28)
Amicangelo, Jay C.
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Lee, Yuan-Pern
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交大名義發表
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應用化學系
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應用化學系分子科學碩博班
The reaction of hydrogen atoms (H) with isoprene (C5H8) in solid para-hydrogen (p-H2) matrices at 3.2 K has been studied using infrared (IR) spectroscopy. Mixtures of C5H8 and Cl-2 were co-deposited in p-H2 at 3.2 K, followed by irradiation with ultraviolet light at 365 nm to produce Cl atoms from the Cl-2, and subsequent irradiation with IR light to produce H atoms from the reaction of the Cl atoms with p-H-2. The H atoms then react with the C5H8 to form H atom addition radicals (C5H9 center dot). Upon 365-nm/IR photolysis, a multitude of new lines appeared in the IR spectrum and, based on the secondary photolysis behavior, it was determined that the majority of the new lines belong to two distinct chemical species, denoted as setX(an intense line at 776.0 cm 1 and 12 other weaker lines) and set Y (an intense line at 766.7 cm(-1) and 12 other weaker lines). Quantum-chemical calculations were performed at the B3PW91/6-311++ G(2d, 2p) level to determine the relative energetics and predict the IR spectra for the four possible isomers of C5H9 center dot that can be produced from the addition of the H atom to the four distinct carbon atoms in C5H8. The newly observed lines of set X and Y are assigned to the 1,2-dimethylallyl (addition to carbon 4) and the 1,1-dimethylallyl (addition to carbon 1) radicals according to comparison with the predicted IR spectra of the possible products. The 1,2-dimethylallyl radical and the 1,1-dimethylallyl radical were predicted to be the most stable isomers, with the latter similar to 8 kJ mol(-1) lower in energy than the former and to have significantly lower barriers than the addition pathways for the two central carbons. The ratio of the 1,1-dimethylallyl to the 1,2-dimethylallyl radicals is estimated to be (1.0 +/- 0.5): 1.0, indicating that the two radicals are produced in similar amounts, which is consistent with the theoretical predictions that the barrier heights are very similar for the H atom addition to the two terminal carbon atoms. Published by AIP Publishing.
Reversible Photocurrent Switching in Ionic and Superionic Conductors of Polycrystalline Silver Iodide
(2018-11-29)
Sabeth, Farzana
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Khaton, Rahima
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Islam, Md. Serajul
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Iimori, Toshifumi
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Ohta, Nobuhiro
Photocurrent switching effect plays vital roles in a number of optoelectronic devices especially for the construction of various logic gates. In the conventional photocurrent switching materials, electrons and holes are the charge carriers. Here we propose that the ionic and superionic photocurrent in some polymorphs of silver iodide is also switchable. We observed that the polarity of photocurrent in the polycrystalline gamma-AgI is positive when an area near the negative electrode is irradiated with visible light and photocurrent switched to negative values while area near the positive electrode is photoirradiated. Polycrystalline alpha-AgI derived from gamma-AgI also shows the photocurrent switching effect, depending on the photoirradiation position. Such a complete polarity switching phenomenon was not obtained in polycrystalline beta-AgI as well as the alpha-AgI derived from beta-AgI. Usually, the polarity of the photocurrent is changed by reversing photoelectrode potential or by using light of different wavelengths or intensities. This study introduces a rather simple way to control the photocurrent switching by changing the position of irradiation of light of constant wavelength and intensity.
The influence on electrical characteristics of amorphous indium tungsten oxide thin film transistors with multi-stacked active layer structure
(2018-11-30)
Ruan, Dun-Bao
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Liu, Po-Tsun
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Gan, Kai-Jhih
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Chiu, Yu-Chuan
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Yu, Min-Chin
In order to effectively enhance the carrier mobility and device stability, simultaneously, a multi-stacked active layer of thin film transistor with a novel type of channel material, amorphous indium-tungsten-oxide, is proposed in this work. Atop-cappingoxygen-rich indium-tungsten-zinc-oxide thin film is used for suppressing the influence of the molecular adsorption or desorption from the ambient at the back channel in the gate bias stress test. In addition, a bottom-bufferingoxygen-rich indium-tungsten-zinc-oxide thin film is deposited to avoid the oxygen vacancy generation during the following thermal process. On the other hand, a 1-nm thick WO3 film is inserted between the high-k gate insulator and active layer, which play important roles as interfacial layer for improving the interface quality and keeping the stability of front channel film. Besides, an HfO2 dielectric film is chosen as gate insulator for realizing the low-voltage operation. As a result, the novel tungsten doped channel material with both-sideoxygen-rich active layer exhibits a high I-ON/I-OFF current ratio of similar to 6x10(7) for low gate leakage current, attributing to the Atop-cappingoxygen-rich thin film. Then, a high field-effect mobility of similar to 27.9cm(2)/V.s and a low sub-threshold swing of 0.079 V/decade are achieved by the good interface quality. This structure with both-sideoxygen-rich active layer exhibits its potential application for the future high-resolution and large-size display manufacture.
Kinetic study of continuous liquid-liquid extraction of wine with real-time detection
(2018-11-30)
Yang, Hui-Hsien
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Dutkiewicz, Ewelina P.
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Urban, Pawel L.
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應用化學系
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Department of Applied Chemistry
Kinetic optimization of continuous liquid-liquid extraction (CLLE) can shorten sample preparation times and reduce losses of labile or volatile analytes. Here, we coupled a downscaled CLLE apparatus with atmospheric pressure chemical ionization interface of triple quadrupole mass spectrometer. Real-time sampling was guided by an Arduino-based programmable logic controller. The recorded datasets were processed to compute the extraction rate constants for the target analytes. The extraction time in subsequent on-line experiments was set to 180 min as a compromise between the reduction of the analysis time and maximizing its yield. Interestingly, off-line analysis of the extract produced different results than on-line analysis pointing to the immanent degradation of the collected extract aliquots. Next, we implemented this hyphenated system in the analysis of red wine samples, which were stored during different periods of time after opening the bottle. The results reveal differences in the depletion of the volatile wine components during storage. (C) 2018 Elsevier B.V. All rights reserved.
AlGaN/GaN MIS-HEMTs With High Quality ALD-Al2O3 Gate Dielectric Using Water and Remote Oxygen Plasma As Oxidants
(2018-12-01)
Wang, Huan-Chung
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Hsieh, Ting-En
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Lin, Yueh-Chin
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Luc, Quang Ho
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Liu, Shih-Chien
We demonstrate the electrical performances of AlGaN/GaN metal-insulator-semiconductor-high electron mobility transistors (MIS-HEMTs) with high quality Al2O3 gate dielectric deposited by plasma enhanced atomic layer deposition using both H2O and remote O-2 plasma as oxygen sources. Excellent gate-dielectric/GaN interface and Al2O3 film quality were obtained, resulting in a very small threshold voltage hysteresis and a low interface trap density. The MIS-HEMT device exhibited high on/off current ratio of similar to 10(10), steep subthreshold slope, small gate leakage current, low dynamic on-resistance degradation, and effectively current collapse suppression. These results indicate that incorporating remote O-2 plasma in the ALD-Al2O3 deposition process is an effective and simple way to provide high quality gate dielectric for the GaN MIS-HEMTs production.
對談洪凌－正義與法理的無血／邪大戮：從Title IX與#MeToo叩問後冷戰政治無意識
(深河出版有限公司, 2018-12-01)
劉璧嘉
;
郭佳
重返「醫師無產階級化」：理論概念與台灣經驗
(深河出版有限公司, 2018-12-01)
陳宗延
Investigating the impacts of guanxi and relationship marketing in port logistics: two cases
(2018-12-01)
Chen, Mu-Chen
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Chang, Kuo-Chien
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Hsu, Chia-Lin
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De Leon, German Alcibiades Vega
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運輸與物流管理系註：原交通所+運管所
This study explores the differential impacts of guanxi and relationship marketing, both at the interpersonal and interorganisational level, within the port logistics industry. We compare the effects of these two marketing approaches on outcome variables to elucidate managerial implications for logistics firms conducting cross-cultural business. The PLS-SEM method is used to analyse data from a survey of logistics companies in Taiwan and Panama. In both countries, interpersonal relationships engender significant effects on interorganisational relationships, and firm performance has significant effects on firm loyalty. As regards the determinants of supply-chain effectiveness and firm performance, we show that interpersonal relationships play a more important role in Taiwan, while interorganisational relationships have more weight in Panama. In other words, Asian companies focus on guanxi marketing at the personal level, while Latin American ones focus on relationship marketing at the interorganisational level. These findings and consequent knowledge can help companies conducting business in Asia and Latin America to adapt to counterpart's cultural business practices.
出走，探索不一樣的人生－芬蘭交換學習心得
(國立陽明大學, 2018-12)
陳亭安
In Celebration of Professor Wen-Hwa Chen's 70th Birthday
(2018-12-01)
Chen, Cha'o-Kuang
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Lin, Zone-Ching
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Chieng, Wei-Hua
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機械工程學系
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Department of Mechanical Engineering
Direct C-H Arylation Polymerization to form Anionic Water-Soluble Poly(3,4-ethylenedioxythiophenes) with Higher Yields and Molecular Weights
(2018-12-01)
Ayalew, Hailemichael
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Wang, Tian-lin
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Wang, Tsai-Hui
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Hsu, Hsiu-Fu
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Yu, Hsiao-hua
A facile and environmentally benign Pd-catalyzed direct C-H arylation polymerization (DAP) has been developed for the syntheses of homo-and copolymers of anionic-group-functionalized 3,4-ethylenedioxythiophenes with high yields (up to 99%), high molecular weights, and narrow polydispersities. The effects of various Pd catalysts, phosphine ligands, and additives on the properties of the polymers have been examined. The method gives anionic poly(3,4-ethylenedioxythiophenes) with higher molecular weights than those produced by the previously reported chemical or electrochemical methods. The method was also used to synthesize polymers functionalized with carboxylic acid groups without the need for protection/ deprotection steps. The resulting polymers can be processed from water or highly polar organic solvents. We also demonstrated a phosphine-free, water-mediated, Pdcatalyzed DAP. The anionic poly(3,4-ethylenedioxythiophenes) were stable in water, and are promising for applications in sensors, drug delivery, and cell engineering.
Multilabeled Value Networks for Computer Go
(2018-12-01)
Wu, Ti-Rong
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Wu, I-Chen
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Chen, Guan-Wun
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Wei, Ting-Han
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Wu, Hung-Chun
This paper proposes a new approach to a novel value network architecture for the game Go, called a multilabeled (ML) value network. In the ML value network, different values (win rates) are trained simultaneously for different settings of komi, a compensation given to balance the initiative of playing first. The ML value network has three advantages: 1) it outputs values for different komi; (2) it supports dynamic komi; and (3) it lowers the mean squared error (MSE). This paper also proposes a new dynamic komi method to improve game-playing strength. This paper also performs experiments to demonstrate the merits of the architecture. First, the MSE of the ML value network is generally lower than the value network alone. Second, the program based on the ML value network wins by a rate of 67.6% against the program based on the value network alone. Third, the program with the proposed dynamic komi method significantly improves the playing strength over the baseline that does not use dynamic komi, especially for handicap games. To our knowledge, up to date, no handicap games have been played openly by programs using value networks. This paper provides these programs with a useful approach to playing handicap games.
在市場中實踐「西藏意識」：印度、尼泊爾流亡藏人的難民經濟
(國立陽明交通大學出版社, 2018-12-01)
潘美玲
在全球化的跨國移工或經濟移民的現象中，本文探討的是非自願移民的難民群體的生存策略與經濟運作機制。主要針對流亡藏人社群，因為其難民的狀態，同時擔負著維繫西藏的文化使命，而發展出來的「西藏意識」（Tibetanness），從政治認同的面向拓展到市場上的經濟實踐，從而影響其生存策略與經濟活動的實踐。透過流亡藏人在印度的冬季毛衣貿易業，以及在尼泊爾發展的西藏地毯產業，以多點民族誌與比較分析策略，檢視流亡藏人如何在這兩個產業市場當中實踐其「西藏意識」，從而構成西藏難民的經濟特色。這種西藏特色有助於市場差異化策略的進行，但也構成了產業發展的限制。印證了博蘭尼所指出市場鑲嵌在社會之中的運作，尤其流亡藏人社會的發展要務，在於為西藏的家園尋求正義，並以維持認同與文化傳統為優先，因此經濟的目的在於維生，是完成西藏志業的工具，從而對於資本主義式的財富積累和壟斷式的擴張，產生了節制的力量，維繫了藏人在流亡處境下族群團結的基礎。
桌球競賽暫停策略之分析
(國立交通大學體育室, 2018-12-01)
王鈞逸
;
Chun-Yi Wang
目的：運動競賽中暫停之申請為一決策行為，本研究旨在瞭解頂尖教練及選手申請暫停的時機，並探討暫停後之效益。方法：以2016年世界桌球錦標賽(World Table Tennis Championship, WTTC)男子團體賽八強選手作為研究對象，並以影片回顧之方式，蒐集半準決賽至決賽之暫停資料，所得數據以描述性統計建立基本資料，並以卡方適合度檢定分析暫停時機其次數之分佈情形。結果：暫停的使用率為83%，暫停局次以第3局的比率最高，局段以中局最多，比分情境最多為連續輸2-3分，暫停後的球權歸屬差異不明顯，領先時申請暫停的比率低於落後時，而暫停後1-4分的勝率約為50%。結論：現今桌球競賽十分重視暫停之申請並徹底執行，且暫停時機有提早之趨勢。而無論領先或落後時申請暫停，均具有正向效益。
Development of Limited-Angle Iterative Reconstruction Algorithms with Context Encoder-Based Sinogram Completion for Micro-CT Applications
(2018-12-01)
Jin, Shih-Chun
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Hsieh, Chia-Jui
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Chen, Jyh-Cheng
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Tu, Shih-Huan
;
Chen, Ya-Chen
Limited-angle iterative reconstruction (LAIR) reduces the radiation dose required for computed tomography (CT) imaging by decreasing the range of the projection angle. We developed an image-quality-based stopping-criteria method with a flexible and innovative instrument design that, when combined with LAIR, provides the image quality of a conventional CT system. This study describes the construction of different scan acquisition protocols for micro-CT system applications. Fully-sampled Feldkamp (FDK)-reconstructed images were used as references for comparison to assess the image quality produced by these tested protocols. The insufficient portions of a sinogram were inpainted by applying a context encoder (CE), a type of generative adversarial network, to the LAIR process. The context image was passed through an encoder to identify features that were connected to the decoder using a channel-wise fully-connected layer. Our results evidence the excellent performance of this novel approach. Even when we reduce the radiation dose by 1/4, the iterative-based LAIR improved the full-width half-maximum, contrast-to-noise and signal-to-noise ratios by 20% to 40% compared to a fully-sampled FDK-based reconstruction. Our data support that this CE-based sinogram completion method enhances the efficacy and efficiency of LAIR and that would allow feasibility of limited angle reconstruction.
A fast and low idle time method for mining frequent patterns in distributed and many-task computing environments
(2018-12-01)
Lin, Chun-Cheng
;
Chung, Sheng-Hao
;
Chen, Ju-Chin
;
Yu, Yuan-Tse
;
Lin, Kawuu W.
Association rules mining has attracted much attention among data mining topics because it has been successfully applied in various fields to find the association between purchased items by identifying frequent patterns (FPs). Currently, databases are huge, ranging in size from terabytes to petabytes. Although past studies can effectively discover FPs to deduce association rules, the execution efficiency is still a critical problem, particularly for big data. Progressive size working set (PSWS) and parallel FP-growth (PFP) are state-of-the-art methods that have been applied successfully to parallel and distributed computing technology to improve mining processing time in many-task computing, thereby bridging the gap between high-throughput and high-performance computing. However, such methods cannot mine before obtaining a complete FP-tree or the corresponding subdatabase, causing a high idle time for computing nodes. We propose a method that can begin mining when a small part of an FP-tree is received. The idle time of computing nodes can be reduced, and thus, the time required for mining can be reduced effectively. Through an empirical evaluation, the proposed method is shown to be faster than PSWS and PFP.