標題: | NEW-TYPE CHITOSAN-BASED HYBRID MACROMOLECULE AND A METHOD FOR PRODUCING OR USING THE MACROMOLECULE |
作者: | LIU Dean-Mo Tung Tsan-Hua Cheng Hongwei |
公開日期: | 21-六月-2012 |
摘要: | The invention discloses the synthesis of a new-type chitosan-based hybrid macromolecule and a method for producing or using the macromolecule. This macromolecule comprises an amphiphatic chitosan and a silicon-based coupling agent that is anchored by a chemical bonding. The method for producing the hybrid macromolecule can be easily operated under ambient environment. The produced macromolecule can be self-assembled in an aqueous environment to form a nanocarrier, and has the ability to efficiently encapsulate drugs for a subsequent sustained release purpose. This self-assembled hybrid nanocarrier demonstrated features of excellent biocompatibility, drug loading ability and cellular uptake efficiency. |
官方說明文件#: | B01J013/02 C08B037/08 |
URI: | http://hdl.handle.net/11536/105165 |
專利國: | USA |
專利號碼: | 20120153520 |
顯示於類別: | 專利資料 |