標題: Stimuli-Responsive Controlled Drug Release from Magnetic-Sensitive Silica Nanospheres
作者: Hu, Shang-Hsiu
Liu, Ting-Yu
Huang, Hsin-Yang
Liu, Dean-Mo
Chen, San-Yuan
材料科學與工程學系
Department of Materials Science and Engineering
關鍵字: Controlled Drug Release;Magnetic;Nanospheres
公開日期: 1-二月-2009
摘要: A novel method for control burst releasing of drug via a high frequency magnetic field (HFMF) from magnetic-sensitive silica nanospheres was developed. The nanospheres were synthesized by a combination of emulsion and sol-gel process with the particles controlled at about 80 nm in diameter. Under repeated exposures to the high frequency magnetic stimulus, the drug release behaviors showed reproducible slow-to-burst profiles while consecutively applying the magnetic stimulus at 10-min switching time and the release profile restored immediately when the stimulus was removed. By taking this non-contact control-burst method, the magnetic silica nanospheres can be designed to treat the cancer therapy and urgent physiological needs.
URI: http://dx.doi.org/10.1166/jnn.2009.C042
http://hdl.handle.net/11536/12745
ISSN: 1533-4880
DOI: 10.1166/jnn.2009.C042
期刊: JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
Volume: 9
Issue: 2
起始頁: 866
結束頁: 870
顯示於類別:會議論文