A Monolithic Lab-on-a-Chip for Electrochemical Detection

Abstract

This paper reports a novel monolithic lab-on-a-chip (LOC) with an electrochemical system embedded in an electrowetting on dielectric (EWOD) microfluidic device for the first time. The fabrication process is compatible with IC technology. This chip could not only merge and transport droplets successfully, but show good electrochemical responses of glucose and glucose oxidase with the sensitivity of 0.028mA/mM and the statistic adjust R-square of 0.9549.