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dc.contributor.authorHuang, Ting-Weien_US
dc.contributor.authorCheng, Nai-Lunen_US
dc.contributor.authorTsai, Ming-Hsuien_US
dc.contributor.authorChiou, Jin-Chernen_US
dc.contributor.authorMang, Ou-Yangen_US
dc.date.accessioned2019-04-03T06:47:09Z-
dc.date.available2019-04-03T06:47:09Z-
dc.date.issued2016-01-01en_US
dc.identifier.isbn978-1-62841-934-4en_US
dc.identifier.issn0277-786Xen_US
dc.identifier.urihttp://dx.doi.org/10.1117/12.2212836en_US
dc.identifier.urihttp://hdl.handle.net/11536/136446-
dc.description.abstractOral cancer is one of the serious and growing problem in many developing and developed countries. The simple oral visual screening by clinician can reduce 37,000 oral cancer deaths annually worldwide. However, the conventional oral examination with the visual inspection and the palpation of oral lesions is not an objective and reliable approach for oral cancer diagnosis, and it may cause the delayed hospital treatment for the patients of oral cancer or leads to the oral cancer out of control in the late stage. Therefore, a device for oral cancer detection are developed for early diagnosis and treatment. A portable LED Induced autofluorescence (LIAF) imager is developed by our group. It contained the multiple wavelength of LED excitation light and the rotary filter ring of eight channels to capture ex-vivo oral tissue autofluorescence images. The advantages of LIAF imager compared to other devices for oral cancer diagnosis are that LIAF imager has a probe of L shape for fixing the object distance, protecting the effect of ambient light, and observing the blind spot in the deep port between the gumsgingiva and the lining of the mouth. Besides, the multiple excitation of LED light source can induce multiple autofluorescence, and LIAF imager with the rotary filter ring of eight channels can detect the spectral images of multiple narrow bands. The prototype of a portable LIAF imager is applied in the clinical trials for some cases in Taiwan, and the images of the clinical trial with the specific excitation show the significant differences between normal tissue and oral tissue under these cases.en_US
dc.language.isoen_USen_US
dc.subjectAutofluorescenceen_US
dc.subjectfilteren_US
dc.subjectoral canceren_US
dc.subjectLEDen_US
dc.subjectinduceden_US
dc.titleLED Induced Autofluorescence (LIAF) Imager with eight multi-filters for Oral Cancer Diagnosisen_US
dc.typeProceedings Paperen_US
dc.identifier.doi10.1117/12.2212836en_US
dc.identifier.journalDESIGN AND QUALITY FOR BIOMEDICAL TECHNOLOGIES IXen_US
dc.citation.volume9700en_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department分子醫學與生物工程研究所zh_TW
dc.contributor.department電機工程學系zh_TW
dc.contributor.departmentInstitute of Molecular Medicine and Bioengineeringen_US
dc.contributor.departmentDepartment of Electrical and Computer Engineeringen_US
dc.identifier.wosnumberWOS:000383614900025en_US
dc.citation.woscount0en_US
Appears in Collections:Conferences Paper


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