標題: | Investigation of nanoparticle-assisted ultrasound therapy for treating implanted breast tumors in mice |
作者: | Kosheleva, Olga Lai, Tsung-Ching Chan, Yung-Chieh Hsiao, Michael Ng, Shok-Li Chen, Chung-Hsuan Chen, Nelson G. 分子醫學與生物工程研究所 Institute of Molecular Medicine and Bioengineering |
關鍵字: | ultrasound;cancer;nanoparticle-assisted ultrasound therapy;ultrasound-nanoparticle interactions |
公開日期: | 1-一月-2017 |
摘要: | The presence of nanoparticles within an ultrasonic field has been previously shown to cause ultrasound to preferentially destroy cancerous cells over corresponding normal cells. Such treatment, termed nanoparticle-assisted ultrasound therapy (NAUT), has now been applied to subcutaneously implanted tumors in mice. Xenografted tumors were exposed to therapeutic ultrasound, with and without intratumoral injections of nanoparticles over a period of 4 weeks. Post-treatment, tumors that received nanoparticle injections were found to be substantially smaller than controls, suggesting that nanoparticle presence significantly increases the efficacy of ultrasonic treatment of solid tumors. |
URI: | http://hdl.handle.net/11536/146178 |
ISSN: | 1944-9399 |
期刊: | 2017 IEEE 17TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO) |
起始頁: | 672 |
結束頁: | 674 |
顯示於類別: | 會議論文 |