標題: Investigation of nanoparticle-assisted ultrasound therapy for treating implanted breast tumors in mice
作者: Kosheleva, Olga
Lai, Tsung-Ching
Chan, Yung-Chieh
Hsiao, Michael
Ng, Shok-Li
Chen, Chung-Hsuan
Chen, Nelson G.
分子醫學與生物工程研究所
Institute of Molecular Medicine and Bioengineering
關鍵字: ultrasound;cancer;nanoparticle-assisted ultrasound therapy;ultrasound-nanoparticle interactions
公開日期: 1-一月-2017
摘要: The presence of nanoparticles within an ultrasonic field has been previously shown to cause ultrasound to preferentially destroy cancerous cells over corresponding normal cells. Such treatment, termed nanoparticle-assisted ultrasound therapy (NAUT), has now been applied to subcutaneously implanted tumors in mice. Xenografted tumors were exposed to therapeutic ultrasound, with and without intratumoral injections of nanoparticles over a period of 4 weeks. Post-treatment, tumors that received nanoparticle injections were found to be substantially smaller than controls, suggesting that nanoparticle presence significantly increases the efficacy of ultrasonic treatment of solid tumors.
URI: http://hdl.handle.net/11536/146178
ISSN: 1944-9399
期刊: 2017 IEEE 17TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO)
起始頁: 672
結束頁: 674
顯示於類別:會議論文