超高解析度500至1000個人工電子耳電極系統及刺激策略之設計與實現

Abstract

國外研究指出在安靜環境中，人工電子耳使用者只需要6 至9 個有效的頻道就有足夠聽 力聽到大多數英語談話。但是目前人工電子耳系統只有16 或24 電極是不足夠給人工電 子耳使用者聽(或欣賞)音樂、聽國語或在吵雜環境中使用。 本子計劃利用主持人創新的虛擬電極技術。此技術凌駕於目前最先進的人工電子耳技 術，提升人工電子耳電極之數目從16 或24 個到500~1000 個虛擬電極，20 倍至40 倍增 加頻率解析度。這將有效的提升傳送到聽神經之頻譜信息(spectral cues)。同時將發展基 於新的虛擬500~1000 電極系統之刺激策略(stimulating strategy)，增加送到聽神經之時域 信息(temporal cues)。最新的研究指出增加頻譜信息與時域信息能增進人工電子耳使用者 在吵雜環境中、聽音樂、聽國語等聽力的效能。 第一年: 1.發展與實現Texas Instrument 32055 數位信號處理器晶片與Analog Device Black Fan 數 位信號處理器晶片的250 與500 個虛擬人工電子耳電極系統. 2.發展與實現以250 與500 虛擬電極系統為本的刺激策略.. 3.轉移人工電子耳語音處理器給子計劃4 作臨床評估與子計劃5 作主觀效能評估. 第二年 1.發展與實現Texas Instrument 32055 數位信號處理器晶片與Analog Device Black Fan 數 位信號處理器晶片的500 與1000 個虛擬人工電子耳電極系統. 2.發展與實現以500 與1000 虛擬電極系統為本的刺激策略.. 3.轉移人工電子耳語音處理器給子計劃4 作臨床評估與子計劃5 作主觀效能評估. 第三年 1.發展與實現Texas Instrument 32055 數位信號處理器晶片與Analog Device Black Fan 數 位信號處理器晶片的1000 個虛擬人工電子耳電極系統. 2.發展與實現以1000 虛擬電極系統為本的刺激策略.. 3.轉移人工電子耳語音處理器給子計劃4 作臨床評估與子計劃5 作主觀效能評估.

Research shows that while 6 to 9 effective channels are sufficient for hearing English speech in quiet environment. It is not enough to listen to speech in noise, music and tonal language, particularlyMandarin Chinese. This sub-project project is attempting to leap-frog the current state of the art cochlear implant technology—to raise the number of cochlear implant electrodes from 16 or 24 to 500~1000 virtual electrodes, thus dramatically improve the spectral cues delivered to the auditory nerves. Stimulating strategies based on the new virtual electrode system will be developed, thus, increasing the temporal cues sent to the auditory nerves. It is expected that the improvement in performance for cochlear implant users hearing in noisy environment, in listening to music, and tonal languages, particularlyMandarin Chinese, will be equally significant. Year 1: 1. Develop and implement a new 250 and 500 virtual electrode system in a TI 32055 DSP chip and an Analog Device Black Fan DSP chip. 2. Develop and implement new stimulating strategies based on the 250 and 500 electrodes system 3. Transfer to the cochlear Implant Speech Processor for clinical evaluation for subproject 4 and subjective performance evaluation for sub-project 5. Year 2: 1. Develop and implement a new 500 and 1000 virtual electrode system in a TI 32055 DSP chip and an Analog Device Black Fan DSP chip. 2. Develop and implement new stimulating strategies based on the 500 and 1000 electrodes system 3. Transfer to the cochlear Implant Speech Processor for clinical evaluation for subproject 4 and subjective performance evaluation for sub-project 5. Year 3: 1. Develop and implement a new 1000 virtual electrode system in a TI 32055 DSP chip and an Analog Device Black Fan DSP chip. 2. Develop and implement new stimulating strategies based on the 1000 virtual electrodes system 3. Transfer to the cochlear Implant Speech Processor for clinical evaluation for subproject 4 and subjective performance evaluation for sub-project 5.