1. 目前位置：
楊裕雄

楊裕雄 Yang, Yuh-Shyong

電子郵件／E-mail： ysyang@faculty.nctu.edu.tw

服務單位／Department：生物科技學院 ／ 生物科技學系

著作期間／Publish Period：1995 - 2014-04-30

著作統計／Statistics

Article（73）
Others（13）
Patents（5）
Plan（47）
Proceedings Paper（10）
Thesis（71）

Article

序號
No.		 標題
Title		 著作日期
Date
1 Association of Interleukin-16 Polymorphisms with Graves' Disease in a Taiwanese Population
 2014-04-30
2 Spatially reinforced Au nano-cavities as a reaction nano-reservoir for trace analysis of DNA hybridization
 2014-02-01
3 Dung-Shen Downregulates the Synergistic Apoptotic Effects of Angiotensin II Plus Leu 27-IGF II on Cardiomyoblasts 2014-01-01
4 A Near-Threshold 480 MHz 78 mu W All-Digital PLL With a Bootstrapped DCO
 2013-11-01
5 Crystal Structures of Vertebrate Dihydropyrimidinase and Complexes from Tetraodon nigroviridis with Lysine Carbamylation METAL AND STRUCTURAL REQUIREMENTS FOR POST-TRANSLATIONAL MODIFICATION AND FUNCTION
 2013-10-18
6 Real-Time and Label-Free Detection of the Prostate-Specific Antigen in Human Serum by a Polycrystalline Silicon Nanowire Field-Effect Transistor Biosensor
 2013-08-20
7 Sloped-Gate Voltage Method for Improving Measurement of Poly-Si Nanowire FET in Aqueous Environment
 2013-05-02
8 Rhubarb inhibits hepatocellular carcinoma cell metastasis via GSK-3-beta activation to enhance protein degradation and attenuate nuclear translocation of beta-catenin
 2013-05-01
9 Improved DNA detection by utilizing electrically neutral DNA probe in field-effect transistor measurements as evidenced by surface plasmon resonance imaging
 2013-03-15
10 Fluorescence assay for protein post-translational tyrosine sulfation
 2013-02-01
11 Tumor Marker Detection by Aptamer-Functionalized Graphene Oxide 2013-01-01
12 Alignment of Stretchable Nanoparticle Chains with Tunable Optical Properties Formed from Molecular Machinery 2013-01-01
13 A nano switch mechanism for the redox-responsive sulfotransferase
 2012-07-15
14 Surface Effect of Assembling Enzyme and Modulation of Surface Enzyme Activity with Electric Potential Stress 2012-06-01
15 Ultrasensitive and label-free detection of pathogenic avian influenza DNA by using CMOS impedimetric sensors
 2012-05-15
16 Label-free Detection of Prostate Specific Antigen Using a Silicon Nanobelt Field-effect Transistor 2012-05-01
17 Microfluidic Synthesis of Microfibers for Magnetic-Responsive Controlled Drug Release and Cell Culture
 2012-03-28
18 Pentacene-Based Organic Thin Film Transistors for Ammonia Sensing
 2012-03-01
19 Recovery Based Nanowire Field-Effect Transistor Detection of Pathogenic Avian Influenza DNA
 2012-02-01
20 Functionalization, re-functionalization and rejuvenation of ssDNA nanotemplates
 2012-01-01
21 Porous Organic TFTs for the Applications on Real-Time and Sensitive Gas Sensors
 2011-08-01
22 Implantation of Post-translational Tyrosylprotein Sulfation into a Prokaryotic Expression System
 2011-02-11
23 Size-modulated catalytic activity of enzyme-nanoparticle conjugates: a combined kinetic and theoretical study
 2011-01-01
24 Probing the sensitivity of nanowire-based biosensors using liquid-gating
 2010-10-22
25 Spectrofluorometric assay for monoamine-preferring phenol sulfotransferase (SULT1A3)
 2010-09-15
26 Catalytic Behaviors in Modulating Enzymatic Activity through Different-sized Gold Nanoparticles 2010-01-01
27 Label-free biosensing of a gene mutation using a silicon nanowire field-effect transistor
 2009-12-15
28 Miniaturized metal semiconductor metal photocurrent system for biomolecular sensing via chemiluminescence
 2009-09-01
29 Miscible ferrofluid patterns in a radial magnetic field 2009-07-01
30 Poly-silicon nanowire field-effect transistor for ultrasensitive and label-free detection of pathogenic avian influenza DNA
 2009-06-15
31 Dimerization Is Responsible for the Structural Stability of Human Sulfotransferase 1A1
 2009-05-01
32 A Phototransistor-Based High-Sensitivity Biosensing System Using 650-nm Light
 2009-05-01
33 A scenario-based stochastic programming model for the control or dummy wafers downgrading problem
 2009-05-01
34 Surface Reaction Limited Model for the Evaluation of Immobilized Enzyme on Planar Surfaces
 2009-04-01
35 A High-Sensitivity CMOS-Compatible Biosensing System Based on Absorption Photometry
 2009-01-01
36 Effect of metal binding and posttranslational lysine carboxylation on the activity of recombinant hydantoinase
 2009-01-01
37 Identification and characterization of two novel cytosolic sulfotransferases, SULT1 ST7 and SULT1 ST8, from zebrafish
 2008-08-29
38 An electrochemical dopamine sensor with a CMOS detection circuit
 2008-07-01
39 Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1)
 2008-03-01
40 Immunohistochemical analysis of a novel dehydroepiandrosterone sulfotransferase-like protein in Drosophila neural circuits
 2008-02-29
41 An enzymatic kinetics investigation into the significantly enhanced activity of functionalized gold nanoparticles
 2008-01-01
42 Ultrasensitive detection of dopamine using a polysilicon nanowire field-effect transistor
 2008-01-01
43 A CMOS-Based Phototransistor for High-Sensitivity Biochemical Detection Using Absorption Photometry 2008-01-01
44 Water passivation effect on polycrystalline silicon nanowires
 2007-11-12
45 Fabrication of a miniature CMOS-based optical biosensor
 2007-06-15
46 Dormancy-break and germination in seeds of Prunus campanulata (Rosaceae): role of covering layers and changes in concentration of abscisic acid and gibberellins 2007-03-01
47 A CMOS-compatible optical biosensing system based on visible absorption spectroscopy 2007-01-01
48 A comparison of two methods for transforming non-normal manufacturing data
 2007-01-01
49 Identification of novel hydroxysteroid-sulfating cytosolic SULTs, SULT2 ST2 and SULT2 ST3, from zebrafish: Cloning, expression, characterization, and developmental expression
 2006-11-01
50 Protein changes between dormant and dormancy-broken seeds of Prunus campanulatal Maxim
 2006-07-01
51 Semiconducting single-walled carbon nanotubes exposed to distilled water and aqueous solution: Electrical measurement and theoretical calculation
 2006-01-30
52 dbPTM: an information repository of protein post-translational modification
 2006-01-01
53 A Bayesian approach to obtain a lower bound for the C-pm capability index
 2005-10-01
54 A simple and low-cost method to fabricate TFTs with poly-Si nanowire channel
 2005-09-01
55 1.2V sub-nanoampere A/D converter
 2005-04-14
56 Fluorometric assay for alcohol sulfotransferase
 2005-04-01
57 Discovery of a novel N-iminylamidase activity: substrate specificity, chemico selectivity and catalytic mechanism
 2005-03-01
58 Applications of microtube array on transtlective liquid crystal displays for backlight efficiency enhancement
 2004-12-01
59 Detection of serum uric acid using the optical polymeric enzyme biochip system
 2004-07-15
60 The design of a novel complementary metal oxide semiconductor detection system for biochemical luminescence
 2004-05-15
61 A novel cold-adapted imidase from fish Oreochromis niloticus that catalyzes hydrolysis of maleimide
 2003-12-12
62 Distributional and inferential properties of the estimated precision C-p based on multiple samples
 2003-11-01
63 Purification of industrial hydantoinase in one chromatographic step without affinity tag
 2003-07-01
64 Mechanism of posttranslational regulation of phenol sulfotransferase: Expression of two enzyme forms through redox modification and nucleotide binding
 2003-06-10
65 Modeling the binding and inhibition mechanism of nucleotides and sulfotransferase using molecular docking 2003-06-01
66 CMOS chip as luminescent sensor for biochemical reactions
 2003-06-01
67 Crystallization and preliminary X-ray diffraction analysis of thermophilic imidase from pig liver
 2003-05-01
68 A single mutation converts the nucleotide specificity of phenol sulfotransferase from PAP to AMP
 2002-10-29
69 The role of metal on imide hydrolysis: metal content and pH profiles of metal ion-replaced mammalian imidase
 2002-10-04
70 Prescription chips
 2002-09-01
71 Identification, purification, and characterization of a thermophilic imidase from pig liver
 2000-07-01
72 Nucleotide binding and sulfation catalyzed by phenol sulfotransferase
 2000-05-19
73 Colorimetric determination of the purity of 3 '-phospho adenosine 5'-phosphosulfate and natural abundance of 3 '-phospho adenosine 5 '-phosphate at picomole quantities
 1998-11-01

Others

序號
No.		 標題
Title		 著作日期
Date
1 Rapid analysis of protein tyrosine sulfation/desulfation 2012-09-01
2 From sequence and structure of sulfotransferases and dihydropyrimidinases to an understanding of their mechanisms of action and function 2010-05-01
3 Facile chemoenzymatic platform for protein tyrosine-sulfate production
 2010-04-01
4 A target-specific approach for the identification of tyrosine-sulfated hemostatic proteins
 2009-07-01
5 A NOVEL FLUOROMETRIC ASSAY OF HUMAN 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHETASE 2008-09-01
6 Neuroimmunological evidence and enzymatic characterization of a novel dehydroepiandrosterone sulfotransferase in Drosophila brain 2006-03-07
7 Cytosolic sulfotransferases and environmental estrogenic chemicals
 2005-01-01
8 A nano-switch regulates the activity of redox-responsive phenol sulfotransferase 2004-05-14
9 Nucleotides as cofactor, inhibitor, and antioxidation and stabilization reagent of phenol sulfotransferase 2001-03-07
10 Effect of pH, metal and temperature on the substrate specificity of a thermophilic imidase from pig liver 2001-03-07
11 Mutation at noncysteine positions eliminates the oxidation/reduction effect on the activity of phenol sulfotransferase. 2000-03-26
12 Mutation at non-cysteine positions eliminates the oxidation/reduction effect on the activity of phenol sulfotransferase. 2000-02-15
13 Reactions of phenol sulfotransferase with nucleotides 1997-07-31

Patents

序號
No.		 標題
Title		 著作日期
Date
1 矽奈米線場效電晶體裝置及作為奈米線生物感測與調控元件，及其製造
 2008-03-01
2 奈米線場效電晶體裝置及作為奈米線生物感測與調控元件，及其製造
 2007-03-01
3 生化感測方法及其感測裝置
 2005-07-21
4 生化感測方法及其感測裝置
 2005-05-16
5 Biochemical sensing device
 2005-05-12

Plan

序號
No.		 標題
Title		 著作日期
Date
1 蛋白質亞硫酸化之生化機制與生物調控 2014
2 以蛋白質體陣列感測器系統化探討亞硫酸化後修飾之功能性蛋白質體-建構亞硫酸化蛋白質體學之生化技術平台(總計畫暨子計畫一)( II ) 2014
3 多晶矽奈米線場效電晶體後製程於生醫感測之應用 2014
4 蛋白質亞硫酸化之生化機制與生物調控 2013
5 多晶矽奈米線場效電晶體後製程於生醫感測之應用 2013
6 以蛋白質體陣列感測器系統化探討亞硫酸化後修飾之功能性蛋白質體－建構亞硫酸化蛋白質體學之生化技術平台(總計畫暨子計畫一)( I ) 2013
7 非侵入性可攜式奈米線氨氣生醫感測-〈總計畫暨子計畫一〉非侵入性可攜式奈米線氨氣生醫感測 2012
8 酪氨酸亞硫酸化蛋白質轉譯後修飾之生物功能 2012
9 多晶矽奈米線場效電晶體後製程於生醫感測之應用 2012
10 酪氨酸亞硫酸化蛋白質轉譯後修飾之生物功能 2011
11 超高靈敏度、無須標記且即時檢測腸病毒之奈米線場效電晶體生物感測器 2011
12 超高靈敏度、無須標記且即時檢測腸病毒之奈米線場效電晶體生物感測器
 2010
13 有機薄膜軟性電子氣體感測在非侵入性檢測上之研發---有機薄膜電晶體生物分子固定化技術與高選擇性氣體感測之研發(總計畫及子計畫一)(III) 2010
14 酪氨酸亞硫酸化蛋白質轉譯後修飾之生物功能 2010
15 超高靈敏度、無須標記且即時檢測腸病毒之奈米線場效電晶體生物感測器 2009
16 有機薄膜軟性電子氣體感測在非侵入性檢測上之研發---有機薄膜電晶體生物分子固定化技術與高選擇性氣體感測之研發(總計畫及子計畫一)(II) 2009
17 發展一套超高靈敏度且即時檢測流感病毒的奈米線場效電晶體生物感測器(II) 2009
18 發展一套超高靈敏度且即時檢測流感病毒的奈米線場效電晶體生物感測器(I) 2008
19 高瞻計畫(內湖高工)-子計畫四---課程評鑑研究(III)
 2008
20 菌種最適培養條件評估及發酵製程放大研究
 2008
21 有機薄膜軟性電子氣體感測在非侵入性檢測上之研發---有機薄膜電晶體生物分子固定化技術與高選擇性氣體感測之研發(總計畫及子計畫一)(I) 2008
22 生化感測與仿生調控功能的奈米結構與生物分子混成系統之研究(III) 2007
23 發展預測蛋白質功能結合/辨識區位之資訊整合工具---子計畫二：從序列、結構與功能探討酵素家族之反應機制(III)
 2007
24 高瞻計畫(內湖高工)-子計畫四---課程評鑑研究(II) 2007
25 高瞻計畫(內湖高工)---子計畫四:課程評鑑研究(I) 2006
26 發展預測蛋白質功能結合/辨識區位之資訊整合工具---（子計畫二）從序列、結構與功能探討酵素家族之反應機制(II) 2006
27 從分子層次到生物行為---探討亞硫酸化之反應機制與功能(II) 2006
28 生化感測與仿生調控功能的奈米結構與生物分子混成系統之研究(II) 2006
29 生化感測與仿生調控功能的奈米結構與生物分子混成系統之研究(I) 2005
30 發展預測蛋白質功能結合/辨識區位之資訊整合工具---（子計畫二）從序列、結構與功能探討酵素家族之反應機制(I)
 2005
31 從分子層次到生物行為---探討亞硫酸化之反應機制與功能(I) 2005
32 組裝式半導體生醫感測裝置之設計與應用
 2004
33 亞硫酸基轉移酵素催化機制與生物功能之研究 2004
34 酚亞硫酸基轉移酵素催化機制之研究與修改(II) 2003
35 生化積體電路及半導體感測晶片之研發---膽固醇檢測晶片 2003
36 酚亞硫酸基轉移酵素催化機制之研究與修改(I)
 2002
37 應用酵素法分離D,L-沙利竇邁 2002
38 酚亞硫酸基轉移酵素催化反應之管制與機制
 2001
39 應用酵素合成光學活性化合物---原料藥關鍵中間體之合成
 2000
40 由酚亞硫酸基轉移酵素之結構與功能探討管制催化亞硫酸基轉移之機制
 2000
41 動物中的嗜熱性酵素---醯亞氨水解酵素反應機制之探討
 2000
42 亞硫酸基轉移之反應機制---酚亞硫酸基轉移酵素之分子模擬、化學變性與定點突變
 2000
43 生物性亞硫酸基轉移機制---核甘酸與亞硫酸基轉移酵素酵素之結合對於其型態變化與與催化反應之影響
 1999
44 (1)結合能對於亞硫酸基轉移機制之影響(2)嗜熱性酵素-醯亞氨水解酵素之反應機制
 1998
45 亞硫酸基轉移酵素在鼠肝中之組成與功能 1997
46 以基因重組表達亞硫酸基轉移酵素之特性 1996
47 亞硫酸基移轉酵素之解毒功能 1995

Proceedings Paper

序號
No.		 標題
Title		 著作日期
Date
1 Novel poly-silicon nanowire field effect transistor for biosensing application
 2009-01-01
2 A Miniature CMOS Optoelectronic Biosensor for Screening Skin-Whitening Agents 2009-01-01
3 A High-Sensitivity CMOS-Compatible Immunosensor Based on the HRP/TMB/Streptavidin System 2008-01-01
4 Gas sensing mechanism in pentacene-based OTFTs 2007-01-01
5 Protein metal binding residue prediction based on neural networks
 2005-02-01
6 Micro-tube array on transflective liquid crystal displays for enhancing the backlight utilization efficiency 2004-01-01
7 Protein metal binding residue prediction based on neural networks 2004-01-01
8 Tradeoff between performance and computation for prediction of real-time MPEG video traffic 2003-01-01
9 Optimal H-infinity prediction algorithm for uncertain non-stationary real-time MPEG VBR traffic 2002-01-01
10 Effects of 3 '-phosphoadenosine 5 '-phosphate on the activity and folding of phenol sulfotransferase
 1998-02-20

Thesis

序號
No.		 標題
Title		 著作日期
Date
1 多晶矽奈米線氨氣感測平台開發與感測機制探討 2013
2 以原態凝膠電泳系統分析鑑定亞硫酸化蛋白質 2013
3 現代台灣中小企業的策略轉型與精實創業之研究-以J 公司為例 2013
4 創新致勝：全球創新企業實證研究 2012
5 單股DNA奈米模版發展與應用 2012
6 表面修飾對奈米線場效電晶體之電訊號特性之影響 2012
7 企業社會責任與管理者權力之探討 2012
8 產品展示的大小或多寡對消費者評價的影響 2012
9 發展谷胱甘肽S-轉移酶融合系統辨別蛋白質亞硫酸化催化位 2012
10 蛋白質酪氨酸亞硫酸化誘導PSGL-1與腸病毒71型VP1外鞘蛋白的結合作用 2012
11 醯亞胺水解酶之金屬數目：脊椎動物與微生物間之差異 2011
12 矽奈米線場效電晶體生物感測平台 2011
13 探討細胞質亞硫酸基轉移酵素之受質篩選機制 2011
14 探討乙醯膽鹼酯酶在固定化和游離狀態下之酵素動力學
 2011
15 水氣的存在與介電層材料的親水性對有機薄膜電晶體感測氨氣的影響 2010
16 由生化分子層次到模式動物實驗之系統性探討酪氨酸亞硫酸化蛋白質體研究 2010
17 0.5V低功率全數位鎖相迴路設計
 2010
18 使用階層式語言模型之大詞彙國語辨認系統
 2010
19 開發可迴復性之流感病毒核酸檢測 2010
20 利用高穩定性的天線式感測閘極多晶矽奈米線場效電晶體以無標誌且快速檢驗方式偵測腸病毒七十一型 2010
21 高通量酵素連結免疫吸附分析法(ELISA)測定蛋白質酪氨酸亞硫酸化 2010
22 多晶矽奈米線場效電晶體於生物感測上的應用 2009
23 研究生物化學特性和結構特性來探討黑腹果蠅蛋白質酪氨酸亞硫酸化酵素
 2009
24 Identification and Characterization of the Enzyme Responsible for Protein Tyrosine Sulfation in Drosophila melanogaster
 2009
25 建立於奈米線場效電晶體上的高靈敏度、無須標記且即時偵測的腸病毒DNA生物感測器
 2009
26 元件製程對於多晶矽奈米線場效電晶體水測電性影響之分析
 2008
27 徑向磁場應用於塗佈技術之研究
 2008
28 奈米線場效電晶體生物感測器於腸病毒71型之高靈敏度、無標記且即時檢測
 2008
29 減弱果蠅神經系統中酪氨酸亞硫酸基轉移酶基因表現量對蛋白質亞硫酸化功能之探討
 2008
30 「固定化酵素動力參數量測平台」之模型建構與計算
 2008
31 亞硫酸基轉移□之定位與功能分析
 2008
32 互補式金氧半導體光二極體晶片葡萄糖與組織胺濃度檢測光學感測系統
 2007
33 從原核表現人類酪氨酸亞硫酸基轉移酶探討其催化活性與功能
 2007
34 酸鹼值與脫落酸在台灣山櫻花種子解除休眠上的影響
 2007
35 人類醯亞胺水解酵素之分子選殖表現及其功能性質探討
 2007
36 果蠅亞硫酸基轉移酵素之選殖及特性研究 2007
37 探討造癭昆蟲基因分子演化關係及蟲癭組織蛋白質體組成-以樟科楨楠屬植物及癭蚋科昆蟲為例
 2007
38 山櫻花種皮和內果皮萃取液對種子發芽的效應
 2006
39 探討蛋白質四級結構對於細胞質亞硫酸基轉移酵素之催化活性與功能的影響
 2006
40 醯亞胺水解酵素催化反應機制-黑青斑河豚之醯亞胺水解酵素分子選殖、表現以及其功能性研究 2006
41 據互補式金氧半導體晶片發展之多功能調頻光學生物感測器
 2006
42 台灣山櫻花種子於休眠至發芽階段種子內亞硫酸基水解酵素活性的變化
 2005
43 蛋白質亞硫酸基轉移酶及3’磷酸腺甘酸5’磷酸硫酸合成酶之螢光檢測法
 2005
44 利用人類脫氫表雄甾酮亞硫酸基轉移酵素之序列與結構比對探討其催化機制與功能
 2005
45 半胱胺酸66與232協同調控氧化還原反應性酚亞硫酸基轉移酵素之催化作用
 2005
46 利用不同來源醯亞胺水解酵素之受質特異性及金屬含量之差異探討其催化機制
 2005
47 醇亞硫酸基轉移酶及3'磷酸腺甘酸5'磷酸硫酸合成酶之螢光檢測法
 2004
48 利用分子模擬尋找醯亞水解酵素之受質 2004
49 運用上光阻的奈米碳管場效電晶體作為離子濃度變化的感測器
 2004
50 組裝式半導體生醫感測元件之設計與應用 2004
51 表面聲波生物感測器固定化技術之研究 2003
52 醯亞胺水解酵素的反應機制 2002
53 發展以互補式金氧半導體為基礎之偵測與定量生物冷光之儀器 2001
54 互補式金氧半導體光感測晶片平臺在生物學上之應用：利用冷光反應設計新的生化檢測平臺 2001
55 不同受質及抑制劑在不同酸鹼環境中影響酚亞硫酸基轉移酵素的催化效應之結果 2001
56 酚亞硫酸基轉移酵素之機制探討 : 氧化還原與核苷酸之影響 2001
57 探討半胱胺酸對酚亞硫酸基轉移酵素的影響 2000
58 酚亞硫酸基轉移酵素之光譜研究:酚亞硫酸基轉移酵素受其結合子誘導所產生之光譜變化 2000
59 小鼠肝臟醯亞胺水解酵素之選殖、表現及再摺疊 2000
60 酚亞硫酸基轉移酵素核甘酸特異性之轉換: 利用定點突變修飾探討PAP 3’-Phosphate與酵素之結合區域 2000
61 用分子模擬探討環狀區胺基酸序列64~69對酚亞硫酸基轉移酵素活性的影響 1999
62 豬肝醯亞胺水解酵素在不同pH和溫度對基質特異性的影響 1999
63 醯亞胺水解酵素之序列分析與表現 1998
64 核□酸與酚亞硫酸基轉移酵素結合誘導構型改變之研究 1997
65 硫胱胺基酸氧化與酚亞硫酸基轉移酵素穩定性關係之探討 1997
66 Probing Nucleotide Binding Site of Phenol Sulfotransferase by Site-Directed Mutangenesis at Lys-65 and Arg-68 1997
67 酚亞硫酸基轉移酵素與Adenosine 3',5'-bisphosphate及其類似物反應之探討 1996
68 豬肝醯亞胺水解酵素的純化和熱性質探討 1996
69 溫度與溶氧量對不同亞硫酸基轉移酵素在大腸桿菌體大量表達的影響 1996
70 不同供應來源式下採購計畫訂定之研究 1996
71 一個擴充式的乘積加密器 1995
生物科技學院