Browsing by Issue Date, starting with "2011"
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Item type:Item, Estimating Achievable Capacity Index based on Multiple Samples(2011-01-01) ;Wang, Tsung-Yin ;Liou, Cheng-Hwai ;Su, Rung-Hung ;Yang, Dong-Yuh工業工程與管理學系This paper investigates the profitability which measures for the newsboy-type product and develops a new index "Achievable Capacity Index", denoted by I-A. It can accurately measure the profitability of newsboy-type product with normally distributed demand. Furthermore, the interrelationship between profitability and I-A is also performed. An unbiased and effective estimator is derived to estimate I-A. Practically, market information regarding demand is obtained from multiple samples rather than single sample. Then we estimate I-A based on multiple samples. Finally, a numerical result is presented to show the probability density function of the unbiased estimator of (I) over cap (A) under different groups and sample sizes. (C) 2011 Published by Elsevier Ltd. Selection and/or peer-review under responsibility of the Asia Pacific Business Innovation and Technology Management SocietyItem type:Item, Novel approach towards the synthesis of skeletally diverse benzimidazole-pyrrolo[1,2-a]quinoxaline by SNAr/Pictet-Spengler reaction under focused microwave irradiation(2011-01-01) ;Maiti, Barnali ;Sun, Chung-Ming ;應用化學系Department of Applied ChemistryIn a study aimed at developing a novel concise approach to the benzimidazole-pyrrolo-[1,2-a]quinoxaline core of medicinal interest, a Pictet-Spengler reaction has been identified that gives direct access to the target compound on soluble polymer support under focused microwave irradiation. The pyrrole moiety has been introduced on polymer immobilized benzimidazole derivatives by SNAr diversification which subsequently transformed to the title compounds via reduction followed by Pictet-Spengler cyclisation with various ketones in good yields and excellent purity. The work described here demonstrates the versatility of the base mediated SNAr reaction coupled with Pictet-Spengler cyclisation in the construction of novel heterocycles.Item type:Item, 多媒體數位環境中科學概念建構之認知動態歷程:心智架構之表徵間聯結、轉換與整合(2011) ;佘曉清 ;SHE HSIAO-CHING國立交通大學教育研究所許多研究指出因科學概念的本質是微觀、抽象、動態的,而造成學 生學習的困難。依據研究者過去的研究 (She, 2004a, 2004b)提出若提供 給學生的的心智架構 (mental set),若能針對概念本質的關鍵特質,則 將可協助學生建構較完整的概念。而研究者認為有必要針對不同本質科 學概念探討多重表徵對於心智模式的呈現的影響。學生是如何處理多重 表徵訊息促進概念建構?學生究竟是如何經由所提供的最佳化心智架 構之表徵間聯結、轉換、 整合,進而建構概念?同時深入研究心智架 構之表徵間聯結、轉換與整合的動態認知歷程與機制?除此之外,究竟 在互動動態歷程中,學生如何相信該心智架構,進而形成自己的科學概 念。是以未來三年的計畫將朝下列的方向進行研究。 第一年:完成開發可以協助學生建構心智架構的多媒體學習內容和 數位環境建置,協助學生建構科學概念。針對不同本質的科學概念的關 鍵特質設計發展可協助學生建構概念之心智架構。深入探討多重表徵對 不同本質科學概念之心智架構建立的訊息處理模式與學習成效。 第二年:正式運用已發展完成之一系列心智架構搭配多重表徵方式 呈現的數位學習內容,正式用於國高中理化、生物學習,藉以找出最佳 化多重表徵呈現的心智架構。更進一步用於學生的學習,同時輔以眼動 儀探討最佳化心智架構之表徵間聯結、轉換、 整合的動態認知歷程對 不同本質科學概念的影響,期望深入理解其機制。 第三年:深入探討何以有些學生能夠經由最佳化心智架構學習模 組,進而建構完整的科學概念,而有些不能。期望運用眼動儀探討其心 智架構之表徵間聯結、轉換、連結動態認知歷程,得以瞭解其機制。除 此之外,將深入探討學生科學概念的建構與學生信念之間的關係。 相信此研究的結果,可以提供不同本質科學概念之心智架構在多重 表徵組合下的訊息處理模式,與心智架構的表徵間之表徵互動、轉換、 整合認知動態歷程,信念與科學概念的關係等。使我們對於科學概念建 構的動態認知歷程與機制能有深入的理解,更有助於未來科學教學該如 何針對不同本質科學概念提供學生最佳化的心智架構,促進科學學習。Item type:Item, Detecting Stability Faults in Sub-threshold SRAMs(2011) ;Lin, Chen-Wei ;Yang, Hao-Yu ;Huang, Chin-Yuan ;Chen, Hung-HsinChao, Mango C. -T.Detecting stability faults has been a crucial task and a hot research topic for the testing of conventional super-threshold 6T SRAM in the past. When lowering the supply voltage of SRAM to the subthreshold region, the impact of stability faults may significantly change, and hence the test methods developed in the past for detecting stability faults may no longer be effective. In this paper, we first categorize the subthreshold-SRAM designs into different types according to their bit-cell structures. Based on each type, we then analyze the difference of its stability faults compared to the conventional super-threshold 6T SRAM, and discuss how the stability-fault test methods should be modified accordingly. A series of experiments are conducted to validate the effectiveness of each stability-fault test method for different types of subthreshold-SRAM designs.Item type:Item, Synthesis, characterization, and photovoltaic properties of a low-bandgap copolymer based on 2,1,3-benzooxadiazole(2011-01-01) ;Jiang, Jian-Ming ;Yang, Po-An ;Chen, Hsiu-Cheng ;Wei, Kung-Hwa材料科學與工程學系PBDTBO, a conjugated polymer comprising benzo[1,2-b:4,5-b']dithiophene (BDT) and 5,6-bis(octyloxy) benzo[c][1,2,5]-oxadiazole (BO) units, exhibits a deep HOMO energy level of -5.27 eV and excellent solubility. A device incorporating PBDTBO and [6,6]-phenyl-C(61)-butyric acid methyl ester (1 : 1, w/w) exhibited a power conversion efficiency of 5.7%.Item type:Item, 領域、論辯立場與論辯方式對知識探究技能與科學認識論的影響(II)(2011) ;洪瑞雲 ;HORNG RUEY-YUN國立交通大學工業工程與管理學系(所)本研究的目的在將去年對科學知識探索技能的研究延伸至科技領域,探討論辯方式(個人、兩人)、論辯立場(正方、反方)對科技知識的探索技能與認識論的影響。科技知識是應用基礎科學的發現來創造出有用的工具。科技知識的建構有賴科技思考技能的運用與對科技知識本質的認識。科技認識論的核心在於瞭解科技是人建構出來的,不是最終的真理,也不是唯一的解。科技知識須有合理的理論解釋與證據。科技學者透過論辯相互詰問,無法被證偽的知識才會被保留下來,論辯因此是科技思考的核心技能。研究中136位大學生被隨機指派至論辯方式(個人、兩人)X論辯立場(正方、反方)的4個情境中對一科技議題進行論辯練習,再以另一科技議題檢測論辯練習的效果。參與者在後測的論辯表現與無論辯練習的控制組比較後發現,雙人正方論辯的練習可提升參與者論辯時的整體反應量與評論量,主要是他們可發現較多議題中證據與論證邏輯的缺失。雙人反方的表現與雙人正方組接近,但有最高的駁斥反應;單人正方則僅在全部證據量上表現較佳,單人反方表現雖比單人正方略佳,但差異不顯著。這些發現與前一年在科學領域的發現不同,顯示人在處理科學與科技議題時知識探索的重點有差異。Item type:Item, 探討以資訊科技為基礎之網絡組織關係品質、敏捷性與知識分享對組織績效之影響(2011) ;楊千 ;YANG CHYAN國立交通大學經營管理研究所愈來愈多研究顯示企業網絡組織的影響在過去幾年來已經是重要的研 究課題。企業受到外部環境的壓力,往往需要縮短產品研發或製造時間,提 早上市。如果只有企業本身的努力,沒有供應商配合,結果會影響產品開發 的成效。 因此,在組織關係品質的影響之下,良好的關係品質可以提升企業間合 作的基礎,並且促進企業溝通與發展。另外,在這樣的緊密關係結合,也可 縮短研發或生產時間,並且在資訊科技的輔助之下進行知識分享。當企業可 以達到上述的目標時,通常可以提升營運績效。由於企業在面臨快速變遷的 營運環境和競爭者的挑戰,如何藉由上述的觀點結合敏捷性來調整企業步 伐,也是當今研究的另一個重點課題。 國內對於上述議題的研究付之闕如,MIS Quarterly 在2009 年的call for paper 也呼應本研究之研究課題,就是與供應商之間的網絡組織如何達 到合作與快速調整企業經營模式。本研究的目的在於瞭解國內企業與供應商 之間如何藉由資訊科技的輔助進行上述活動,改善營運體質,縮短產品上市 時間以爭取競爭優勢。藉由本研究的調查分析,可以提出相關的研究成果供 學術界與實務界參考。Item type:Item, Impact of Negative-Bias-Temperature-Instability on Channel Bulk of Polysilicon TFT by Gated PIN Diode Analysis(2011) ;Huang, Chen-Shuo ;Liu, Po-Tsun ;光電工程學系 ;顯示科技研究所Department of PhotonicsIn this study, negative-bias-temperature-instability (NBTI) stress induced interface, and bulk states of polycrystalline silicon (poly-Si) film were identified by using gated poly-Si P-intrinsic-N (PIN) diodes. The generation of reverse current was proportional to the quantity of defects in the poly-Si of the gated diode device. Experimental results revealed NBTI degradation has a spatial distribution in the poly-Si film and demonstrated that the resultant generation of poly-Si bulk states causes the elevated drain leakage current of thin-film transistors (TFTs). We conclude that grain boundaries, with enriched hydrogenated silicon bonds in the bulk of poly-Si, interact electrochemically with hole-carriers. (C) 2011 The Electrochemical Society. [DOI: 10.1149/1.3551463] All rights reserved.Item type:Item, A novel dual-structure, self-healable, polysaccharide based hybrid nanogel for biomedical uses(2011) ;Lin, Li-Jih ;Larsson, Mikael ;Liu, Dean-Mo ;材料科學與工程學系Department of Materials Science and EngineeringA new unique dual-structure hydrogel composed of nanostructures of amphiphilic chitosan (CHC) dispersed in a sodium alginate matrix (SAL) is presented. The successful creation of the composite is based on combining chitosan and sodium alginate without precipitation or agglomeration, which has not been previously reported. The CHC/SAL composite gels present a number of properties making them attractive for biomedical applications, in particular as implantable depot gels or in dermal applications. The gels are shown to form rapidly upon exposure of the combination solution to Ca(2+) containing gelation medium. The formed gels have storage moduli similar to soft tissue and display shear reversible gelation with fast recovery of mechanical properties, in addition to self-healing capability at certain compositions. The gels exhibit moderate swelling in deionized water and low swelling in simulated body fluid and cell culture media. The drug release from the composite gels is demonstrated using the hydrophobic drug all-trans retinoic acid, which is used in cancer and skin disorder therapies. The drug release initially occurs through a Fickian mechanism for a fraction of the loaded drug, where the fraction released during this process depends on release media and gel composition. A large fraction of the loaded drug can be retained for long term depot drug delivery. Furthermore, the CHC/SAL gels are determined to have low toxicity and skin irritation.Item type:Item, Highly Reflective Ag/La Bilayer Ohmic Contacts to p-Type GaN(2011) ;Chen, I-Chen ;Chen, Yi-Dar ;Hsieh, Chih-Chien ;Kuo, Cheng-HuangChang, Li-ChuanA new Ag/La bilayer metal contact scheme has been developed for producing high reflectance and low contact resistivity ohmic contacts to p-GaN. An excellent reflectance of over 91% at 460 nm wavelength and low specific contact resistivity of 1.6 x 10(-4) Omega cm(2) were obtained from Ag/La (150/20 nm) contact annealed at 450 degrees C for 1 min. The La overlayer was oxidized to form La(2)O(3) when exposed to air, which effectively suppresses exposure of the Ag layer to oxygen atmosphere during annealing, leading to a good ohmic contact with smooth surface morphology and high reflectance. Additionally, Ag/La contacts show excellent thermal stability after a long thermal annealing at 300 degrees C in air ambient. (C) 2011 The Electrochemical Society. [DOI: 10.1149/1.3533673] All rights reserved.Item type:Item, ABAKA: An Anonymous Batch Authenticated and Key Agreement Scheme for Value-Added Services in Vehicular Ad Hoc Networks(2011-01-01) ;Huang, Jiun-Long ;Yeh, Lo-Yao ;Chien, Hung-Yu ;資訊工程學系Department of Computer ScienceIn this paper, we introduce an anonymous batch authenticated and key agreement (ABAKA) scheme to authenticate multiple requests sent from different vehicles and establish different session keys for different vehicles at the same time. In vehicular ad hoc networks (VANETs), the speed of a vehicle is changed from 10 to 40 m/s (36-144 km/h); therefore, the need for efficient authentication is inevitable. Compared with the current key agreement scheme, ABAKA can efficiently authenticate multiple requests by one verification operation and negotiate a session key with each vehicle by one broadcast message. Elliptic curve cryptography is adopted to reduce the verification delay and transmission overhead. The security of ABAKA is based on the elliptic curve discrete logarithm problem, which is an unsolved NP-complete problem. To deal with the invalid request problem, which may cause the batch verification fail, a detection algorithm has been proposed. Moreover, we demonstrate the efficiency merits of ABAKA through performance evaluations in terms of verification delay, transmission overhead, and cost for rebatch verifications, respectively. Simulation results show that both the message delay and message loss rate of ABAKA are less than that of the existing elliptic curve digital signature algorithm (ECDSA)-based scheme.Item type:Item, Virtual Touch 3D Interactive System for Auto-Stereoscopic Display with Embedded Optical Sensor(2011) ;Huang, Yi-Pai ;Wang, Guo-Zhen ;Ma, Ming-Ching ;Tung, Shang-YuHuang, Shu-YiThe traidational 3D interactive sysetm which uses CCD camera to capture image is difficult to operate on near range for mobile applications. Therefore, 3D interactive display with embedded optical sensor was proposed. Based on optical sensor based system, we proposed four different methods to support differenct functions. T mark algorithm can obtain 5-axis information (x, y, z,theta, and phi) of LED no matter where LED was vertical or inclined to panel and whatever it rotated. Sequential mark algorithm and color filter based algorithm can support mulit-user. Finally, bare finger touch system with sequential illuminator can achieve to interact with auto-stereoscopic images by bare finger. Furthermore, the proposed methods were verified on a 4-inch panel with embedded optical sensors.Item type:Item, 最佳停止問題與套利(2011) ;許元春 ;SHEU YUAN-CHUNG國立交通大學應用數學系(所)本計畫探討二個和財務數學有密切關係的數學問題。我們首先探討報 酬函數是二邊形式的最佳停止問題。這問題和新奇選擇權的定價問題有密 切的關聯,我們將在跳躍-擴散過程的假設下,探討這方面的相關問題。另 外一方面,我們將探討隨機資產理論-最佳套利的問題。隨機資產理論是 Fernholz 在1990, 2001 發展的一套理論。除了實務的應用外,它也提供了 很多具有挑戰性及有深度的理論問題。在本計畫裡,我們將試著解決一些 和最佳套利相關的open problems,同時也將把文獻上的相關結果應用到能 真正捕捉到市場特性的理論模型。Item type:Item, The Influence of Relative Humidity on Nanoparticle Concentration and Particle Mass Distribution Measurements by the MOUDI(2011) ;Chen, Sheng-Chieh ;Tsai, Chuen-Jinn ;Chen, Hong-Dar ;Huang, Cheng-YuRoam, Gwo-DongA humidity control system was operated upstream of two collocated-MOUDIs (micro-orifice uniform deposit impactors) for sampling ambient aerosol particles. One MOUDI used silicone-grease-coated aluminum foils (ALs) as the impaction substrates and was considered as the reference impactor, while the other used uncoated ALs or uncoated Teflon filters (TFs) as the impaction substrates for quantifying the effect of different relative humidities (RHs) and impaction substrates on the PM(0.1) concentrations and mass distributions of ambient PMs. Test results showed that decreasing RH in general increased particle bounce from uncoated substrates with the bounce from uncoated ALs being more severe than that from uncoated TFs. Particle bounce did not influence the overall mass distribution of ambient fine particles when RH ranged between 40% and 80%, whereas it led to undersampling of particles greater than 2.5 mu m in aerodynamic diameter severely. Oversampling of PM(0.1) occurred by as much as 95%-180% or 25%-55% when the MOUDI used uncoated ALs or TFs, respectively, as RH was reduced from 50% to 25%. Particle bounce was found to be negligible, and PM(0.1) and PM(2.5) could be sampled accurately with less than 5% error at the RH of 75%-80% or 65%-80% when uncoated ALs or TFs were used, respectively.Item type:Item, Analysis and Implementation of a Model-free Approach in Network-induced Delay Compensation for Remote Control Systems(2011) ;Lai, Chien-Liang ;Hsu, Pau-Lo ;電機工程學系Department of Electrical and Computer EngineeringWith the rapid development and implementation of Internet technologies, well-designed/tuned controllers obtained from control design without network are desired, which can be further realized in remote control systems directly. Theoretically, available networked control system (NCS) designs are developed with a known system model and time delay. However, the nature of network-induced delay is unpredictable, which depends on network protocol and hardware, and available design approaches usually become impractical in real concerns. The study presents an NCS structure with the proposed perfect delay compensation (PDC) scheme, which is constructed with modified butterfly elements to deal with unknown delay effects without system model and delay information. Both analytical and simulation results prove that the proposed model-free PDC scheme effectively compensates for the unknown network-induced delays. Furthermore, the proposed PDC is carried out using Ethernet, and a well-tuned PI controller for the AC servo motor was directly networked to the remote control system. Experimental results indicate that the proposed PDC renders satisfactory and desirable design results in real NCS applications.Item type:Item, 研究自動迴歸技術在提升影片播放速率與多重描述視訊編碼上之應用(2011) ;蔡文錦 ;Tsai Wen-Jiin國立交通大學資訊工程學系(所)自動迴歸分析(auto-regression analysis) 是在統計學上的一種方法,主要是對資料之間的關係建立模型,目的在於了解資料間是否相關,以便觀察或預測我們感興趣的資料。自動回歸的技術可用在影像或視訊資料上,對已知的點(pixel)建模去預測不存在的點或重建遺失的點。因此,在一些應用如: 增加影像解析度,增加視訊播放速率(frame rate up-conversion, FRUC),錯誤隱藏方法(error concealment)等當中,可以看到使用該技術的例子。在現有的方法中,有的只利用到資料在空間上的關係、有的則只利用到時間上的關係、有的雖然同時利用空間與時間的關係,但所建出的回歸模型太複雜,需要求解的回歸係數太多,也往往需iteration多次才能得到較佳解,不適用在實際的應用中。有鑑於此,本計畫擬進行的研究之一,是改善目前在FRUC應用中的迴歸技術。 另一方面,多重描述編碼法(Multiple Descriptor Coding,簡稱MDC)是一種將影片切割成多個子影片(或稱描述檔,description)的視訊編碼法,非常適合用於網路上的影音串流的應用中。由於它將高頻寬的影音資料切割成多個低頻寬的描述檔,使得低階設備也能參與上載或下載較低頻寬的描述檔,而高階設備則能藉著接收多個描述檔來解出較高品質的影片。此外,由於多重描述編碼所切割出來的描述檔是可以被個別獨立解碼的,且各描述檔在傳輸時可走不同路徑,因此,有封包遺失時可藉由其他描述檔的內容來加以修復,大幅減低封包遺失對影片品質的影響。此編碼法雖然能為設備的異質性與網路的封包遺失提供解決之道,然而編碼效能差卻是它主要的問題所在。在多重描述編碼中,因為資料間的關係被切割分散在不同描述檔中,無法充分利用,造成整體編碼的資料量遠高於一般標準編碼所產生的資料量。因此,本計畫擬進行的另一部份研究,是將回歸分析技術用於多重描述編碼中,以達到減少多餘的資料量,並維持容錯能力的目的。 此研究計畫中,我們預計以兩年為期完成以下兩個目標:1.改善目前在增加視訊播放速率(frame rate up conversion)應用中的迴歸技術; 2.將回歸技術用在多重視訊編碼上。第一年的研究著重在減少使用回歸技術之計算複雜度,並進一步提升其所產生的畫面品質,使其更適用在實際系統中。我們擬為資料的空間與時間相關性分別建構不同的回歸模型,再設計一個選擇適當回歸模型的機制,來達到減少計算複雜度並維持原有畫面品質的目的;同時我們也將利用動態改變回歸模型中使用的training window大小,來進一步提升畫面品質。第二年的研究著重在將回歸技術用在多重描述視訊編碼上,希望利用少量的 redundancy,達到較佳的資料容錯能力。由於回歸技術能為資料間的關係建模,我們的作法是在描述擋內加入回歸係數,以保留資料間的相關性,由於回歸係數的資料量遠小於原始資料的量,因此我們預期所使用的方法能用少量的 redundancy,達到不錯的容錯能力。Item type:Item, 組內相關係數指標之比較(2011) ;謝國文 ;Shieh Gwowen國立交通大學管理科學系(所)本研究旨在探討單因子隨機模式中,兩種組內相關係數指標的性質,包括著名的 ICC(1)和修正的Eta-Squared 估計式。將以(1)估計理論觀點和(2)估計表現優劣等兩種不 同角度進行比較。藉由觀念解析和數值分析的結果,提供如何選擇組內相關係數指標的 明確建議。Item type:Item, 利用智慧型手機以詢問回覆機制收集即時交通路況之設計與評估(2011) ;張明峰 ;Chang Ming-Feng國立交通大學資訊工程學系(所)傳統利用GPS探偵車收集交通資訊的方法,一般採用探偵車週期性回報,或經過特定地點時回報,也就是,交通路況在固定時間點或固定地點被探偵車取樣。這種取樣的方式並不能保證能偵測到交通路況的動態變化,因為交通路況同時在時間軸和空間面上動態變化。在此一計畫,我們提出創新的動態交通資訊收集方法。我們利用配備GPS接收器與加速度偵測器之智慧型手機偵測交通路況,並採用詢問與回覆機制收集即時動態交通路況。首先,我們將分析高速公路與平面道路的車流模式。其次,我們決定智慧型手機可偵測的交通路況與事件,並設計其演算法與開發程式。第三,我們設計以詢問與回覆機制收集動態交通資訊之演算法與開發程式。基本的構想是:交通資訊中心(Traffic Information Center, TIC)根據目前收集的交通路況,以區域廣播的方式要求各路段的探偵車所需偵測與回報的事件。如此,交通路況在時間與空間上的動態變化都能即時的被探偵車偵測到,並回報給TIC。為了驗證與評估此一方法,我們也將利用交通模擬軟體VISSIM產生高速公路與平面道路在各種合理的車流模式組合下之車輛軌跡與速度。我們以這些軌跡作為路面實況,將用以驗證我們的以詢問與回覆機制之動態交通資訊收集方法,並評估其效能。此外,我們也將在高速公路與平面道路進行實際路測,紀錄車型軌跡與加速度偵測器記錄。這些記錄可用以比對VISSIM軌跡之真實性,也可以用以驗證智慧型手機端之事件偵測程式。Item type:Item, 組織後設結構行為與科技調適對ERP科技成功吸收的權變模式(2011-01-01) ;周斯畏 ;陳昭宏 ;陳慶文 ;Shih-Wei ChouCharles Chen組織如何改善ERP系統的績效仍然是一個重要的議題。針對此問題,本研究根據制度化情境、科技調適理論與科技吸收理論發展出研究模型,並實證管理層支持的後設結構行爲對ERP科技吸收的主影響,和檢驗ERP科技調適如何調節(干擾)管理層支持的後設結構行爲與ERP科技吸收之間的關係。經由201家台灣製造業問卷調查,驗證本研究之權變模型,模型之假設大多獲得顯著性結果。於討論章節部分,並陳述相關意涵供實務管理者與學術研究者參考。Item type:Item, 設計及合成同質或是異質雙辨識之變構性芳杯感測分子(2011) ;鍾文聖 ;CHUNG WEN-SHENG國立交通大學應用化學系(所)設計及合成同質或是異質雙辨識之變構性芳杯感測分子 本計畫將著重於合成及設計新穎的異質以及同質雙辨識之變構性芳杯、或是 硫芳杯感測分子。這些感測分子對於陽離子、陰離子、或是離子進行逐步或是協 作性的辨識對將可利用螢光、循環伏安法、核磁共振等的光譜法研究。我們也將 探討這些感測材料運用於生物影像或是感測元件之可行性。 1. 俄方莫斯科大學將合成具有分子內或分子間的2,2’-雙吲哚架橋的螢光芳杯以 及尿素芳杯管,然後研究它們的異質雙辨識或是離子通道性質。 2. 俄方莫斯科大學將合成具有1,3-交錯構形的芳杯冠醚,此冠醚的上、下緣將修 飾beta-酮基酸以及醯胺,然後研究它們的異質陽離子變構性雙辨識。 3. 交大這邊將合成芳杯下緣具有醯胺以及beta-胺基 alpha,beta-不飽和酮取代 基,用於異質雙辨識。 4. 交大這邊也將合成具有螢光變構性雙辨識芳杯,用於仿生物研究之探討。 5. 下緣具有各種五員雜環(例如: 氧雙唑、吡唑、硫唑)取代的芳杯將利用1,3-偶 極環化加成然後開環的協議方法合成。 6. 在此計畫中,每年都將有雙方的研究人員互訪,交大這邊將學習如何利用俄 方所開發的合成方法合成雙吲哚架橋螢光芳杯以及尿素芳杯管,而俄方則將 利用交大的螢光、紫外可見光譜儀技術協助他們進行這些新型螢光感測分子 之研究。 透過此國際交流合作計畫,我們希望能將俄方與我方的研究優點做互補,發 展出全新的仿生物之感測材料。吾人相信這些新穎的材料在生物影像或是感 測元件之開發上將深具潛力。