Browsing by Issue Date, starting with "2012-05-15"

Now showing 1 - 20 of 36455

Precipitation of large Ag3Sn intermetallic compounds in SnAg2.5 microbumps after multiple reflows in 3D-IC packaging
(2012-05-15)
Yang, Ruo-Wei
;
Chang, Yuan-Wei
;
Sung, Wei-Chi
;
Chen, Chih
;
材料科學與工程學系
Microbumps have been adopted as interconnects between Si chips in 3D integrated-circuit packaging. The solder volume of a microbump decreases dramatically due to fine-pitch requirement and it is approximately two orders smaller in magnitude than that of a traditional flip-chip solder joint. The metallurgical reactions in the microbumps may behave quite differently to those in flip-ship bumps. Liquid-state metallurgical reactions were examined in SnAg2.5 microbumps with Ni metallization. The results indicate that large particles of Ag3Sn intermetallic compounds (IMCs) precipitate after a 10-min reflow on microbumps with 4.0-mu m-thick solder, which does not occur with flip-chip solder bumps. It is proposed that the Ag concentration in the remaining solder may increase as Sn reacts with Ni. The increase in the Ag concentration is mainly responsible for the occurrence of the large Ag3Sn precipitates. The formation of these Ag3Sn IMCs would be detrimental to the mechanical properties of the microbumps. (C) 2012 Elsevier B.V. All rights reserved.
Design of Low-Threshold Photonic Crystal Surface-Emitting Lasers
(2012-05-15)
Hung, Chih-Tsang
;
Syu, Yu-Cheng
;
Wu, Tzeng-Tsong
;
Lu, Tien-Chang
;
光電工程學系
We have investigated the influence of various thicknesses on different layers in GaAs-based photonic crystal surface-emitting lasers (PCSELs), by using the transfer matrix and coupled wave methods to increase the vertically optical confinement factor and to reduce the threshold gain. In addition, the relationship between the threshold gain and the filling factor has been considered. This letter provides an efficient calculation method for designing square-lattice-type PCSEL structures, which shall be useful for the fabrication of low-threshold PCSELs in the near future.
Fabrication of micro-flow channels for metallic bipolar plates by a high-pressure hydroforming apparatus
(2012-05-15)
Hung, Jung-Chung
;
Lin, Chih-Chia
;
機械工程學系
;
Department of Mechanical Engineering
High aspect-ratio micro-flow channels on bipolar plates have the advantage of improving fuel cell performance. This study forms micro-flow channels with a high aspect ratio by increasing the forming pressure during the hydroforming process. This study designs and constructs a mechanical apparatus to enable a two-stage pressure increase in the hydroforming process. A high-pressure container is designed with three-layered tapered cylinders to sustain 1230.17 MPa working pressures, and a special seal component is designed to seal the high-pressure fluid and maintain high pressure. The feasibility of this high-pressure hydroforming technique is verified in preliminary tests. The investigation indicates that the aspect ratio of micro-flow channels can reach 0.468 when a hydrostatic pressure of 250 MPa is applied. Compared with the maximum aspect ratio of 0.31 formed using the traditional hydroforming process, the aspect ratio of micro-flow channels in this study was 51% higher, which enables the fuel cells with metallic bipolar plates to meet both performance and manufacturing requirements. (C) 2012 Elsevier B.V. All rights reserved.
Ultrasensitive and label-free detection of pathogenic avian influenza DNA by using CMOS impedimetric sensors
(2012-05-15)
Lai, Wei-An
;
Lin, Chih-Heng
;
Yang, Yuh-Shyong
;
Lu, Michael S. -C.
;
生物科技學系
This work work presents miniaturized CMOS (complementary metal oxide semiconductor) sensors for non-faradic impedimetric detection of AIV (avian influenza virus) oligonucleotides. The signal-to-noise ratio is significantly improved by monolithic sensor integration to reduce the effect of parasitic capacitances. The use of sub-mu m interdigitated microelectrodes is also beneficial for promoting the signal coupling efficiency. Capacitance changes associated with surface modification, functionalization, and DNA hybridization were extracted from the measured frequency responses based on an equivalent-circuit model. Hybridization of the AIV H5 capture and target DNA probes produced a capacitance reduction of -13.2 +/- 2.1% for target DNA concentrations from 1 fM to 10 fM, while a capacitance increase was observed when H5 target DNA was replaced with non-complementary H7 target DNA. With the demonstrated superior sensing capabilities, this miniaturized CMOS sensing platform shows great potential for label-free point-of-care biosensing applications. (C) 2012 Elsevier B.V. All rights reserved.
Identification of Protein Domains on Major Pilin MrkA That Affects the Mechanical Properties of Klebsiella pneumoniae Type 3 Fimbriae
(2012-05-15)
Chan, Chia-Han
;
Chen, Feng-Jung
;
Huang, Ying-Jung
;
Chen, Shin-Yu
;
Liu, Kuo-Liang
The Klebsiella pneumoniae type 3 fimbriae are mainly composed of MrkA pilins that assemble into a helixlike filament. This study determined the biomechanical properties of the fimbriae and analyzed 11 site-directed MrkA mutants to identify domains that are critical for the properties. Escherichia coli strains expressing type 3 fimbriae with an Ala substitution at either F34, V45, C87, G189, T196, or Y197 resulted in a significant reduction in biofilm formation. The E. coli strain expressing MrkAG189A remained capable of producing a normal number of fimbriae. Although F34A, V45A, T196A, and Y197A substitutions expressed on E. coli strains produced sparse quantities of fimbriae, no fimbriae were observed on the cells expressing MrkAC87A. Further investigations of the mechanical properties of the MrkAG189A fimbriae with optical tweezers revealed that, unlike the wild-type fimbriae, the uncoiling force for MrkAG189A fimbriae was not constant. The MrkAG189A fimbriae also exhibited a lower enthalpy in the differential scanning calorimetry analysis. Together, these findings indicate that the mutant fimbriae are less stable than the wildtype. This study has demonstrated that the C-terminal beta strands of MrkA are required for the assembly and structural stability of fimbriae.
Optoelectronic memory device and method for manufacturing and measuring the same
(2012-05-15)
Wei Kung-Hwa
;
Sheu Jeng-Tzong
;
Chen Chen-Chia
;
Chiu Mao-Yuan
The present invention provides an optoelectronic memory device, the method for manufacturing and evaluating the same. The optoelectronic memory device according to the present invention includes a substrate, an insulation layer, an active layer, source electrode and drain electrode. The substrate includes a gate, and the insulation layer is formed on the substrate. The active layer is formed on the insulation layer, and more particularly, the active layer is formed of a composite material comprising conjugated conductive polymers and quantum dots. Moreover, both of the source and the drain are formed on the insulation layer, and electrically connected to the active layer.
Asymptotic limit in a cell differentiation model with consideration of transcription
(2012-05-15)
Friedman, Avner
;
Kao, Chiu-Yen
;
Shih, Chih-Wen
;
應用數學系
;
Department of Applied Mathematics
T cells of the immune system, upon maturation, differentiate into either Th1 or Th2 cells that have different functions. The decision to which cell type to differentiate depends on the concentrations of transcription factors T-bet (xi) and GATA-3 (x2). These factors are translated by the mRNA whose levels of expression, y(1) and y(2), depend, respectively, on xi and x2 in a nonlinear nonlocal way. The population density of T cells, phi(t, x(1), x(2), y(1), y(2)), satisfies a hyperbolic conservation law with coefficients depending nonlinearly and nonlocally on (t, x(1), x(2), y(1), y(2)). while the x(i), y(i) satisfy a system of ordinary differential equations. We study the long time behavior of and show, under some conditions on the parameters of the system of differential equations, that the gene expressions in the T-cell population aggregate at one, two or four points, which connect to various cell differentiation scenarios. (C) 2012 Elsevier Inc. All rights reserved.
辨識人體移動行為之方法及系統
(2012-05-16)
羅棨鐘
;
吳宗衡
;
陳昭佑
;
郭倫嘉
;
曾煜棋
本揭露之辨識人體移動行為之方法實施例包含下列步驟:擷取一用以辨識人體移動行為之慣性量測元件之連續量測値。若該等連續量測値符合一特定之人體行為特徵,則分割該等連續量測値以產生至少一人體移動行為特徵波型。離散化該至少一人體移動行為特徵波型以產生至少一人體移動行為離散數列。比對該至少一人體移動行為離散數列和參考人體移動行為離散數列以決定該慣性量測元件所對應之人體移動行為。
處理一分頻多工訊號之系統及方法
(2012-05-16)
王海薇
;
林大衛
;
桑梓賢
一種處理一分頻多工訊號的方法,該分頻多工訊號在通道上傳輸,且該方法包含接收該分頻多工訊號,其中該分頻多工訊號的各載波上存在一殘留的載波間干擾與一通道雜訊,且該殘留的載波間干擾來自時變通道或載波頻率漂移,並對該分頻多工訊號進行環字首移除和離散傅利葉轉換,以獲得一頻域訊號,並分析該頻域訊號以獲得該頻域訊號之相鄰載波上的該殘留的載波間干擾與該通道雜訊之相關函數統計特性,且根據該相關函數統計特性,對該分頻多工訊號進行一通訊訊號處理。
應用時間反轉法之觸控面板之定位及力回饋方法
(2012-05-16)
白明憲
;
蔡耀坤
本發明提供一種應用時間反轉法之觸控面板之定位及力回饋方法,其係依據平板理論建立一彈性平板之平板模型及脈衝響應,再依據脈衝響應及時間反轉法建立一數學模型,當外力擊打於彈性平板上,使被擊打之觸控點產生一觸控訊號,設於彈性平板角落之感測器會接收觸控訊號,並利用模擬器將觸控訊號依據數學模型轉換成一時間反轉訊號,反向發送回觸控點,模擬出時間反轉訊號於彈性平板上反向振盪之波形,以定位出觸控點之位置。
自動化分析與分類惡意程式之方法及系統
(2012-05-16)
江易達
;
林盈達
;
吳育松
;
賴源正
一種自動化分析與分類惡意程式之方法及系統,適用於自動化分析一待比對程式是否為一已知惡意程式。該方法包含:提供該已知惡意程式之系統函數編號序列;執行該待比對程式,同時將該待比對程式所呼叫之系統函數之編號記錄成一待比對系統函數編號序列;運算該待比對系統函數編號序列以及該已知惡意程式之系統函數編號序列間之一相似度;及若該相似度小於等於一相似度門檻値,則判定該待比對程式與該已知惡意程式為不同程式。
敗犬女王:明治時期的女流作家-?口一葉
(2012-05-16)
廖秀娟
;
開放教育推動中心
;
Open Education Office
課程首頁本課程是由交通大學新文藝復興閱讀計畫提供。 96 年 8 月當各大學紛紛摩拳擦掌準備迎接新生的同時，交通大學校長吳重雨則因為一則來自於七月份泰晤士報，有關於英國首相布朗公布其夏日讀書清單的新聞中，看到了他對知識的尊重。在這同時，吳重雨校長也思考著，要如何為學生準備追求知識的環境和激發他們對知識的尊重與喜愛。台積電張忠謀董事長曾陳述他 18 歲進入哈佛那一年，博覽文史哲理工經典群籍，至此奠定了他求知的基礎，並借海明威名言，將其改為「哈佛這一年為人生可帶走的盛宴。」吳重雨校長以張董事長的學習為借鏡，認為學生固然能藉由自我閱讀的方式學習到豐沛的知識，但透過名人、大師親臨現場地介紹經典書籍，更能加深學子們對於書籍的認識與興趣，這也是「新文藝復興閱讀計劃」 ( 以下簡稱 : 「經典名著選讀」 ) 活動展開籌劃的緣由。於是，吳重雨校長便積極敦請「交大通識教育委員會」，接手籌備本計劃的相關活動，而該中心也成為實際施行本計畫的策動、開課以及認證單位。至此，期許交大學子藉由閱讀、聽講來提昇人文素養、開拓視野的「新文藝復興閱讀計劃」，就此展開。
訊號還原方法及訊號還原裝置
(2012-05-16)
陳巍仁
;
盧台祐
;
區威文
本發明係揭露一種訊號還原方法及使用該訊號還原方法之訊號還原裝置。本發明訊號還原方法包含產生本地訊號並根據外界所接收之接收訊號及本地訊號之間的頻率差輸出中頻訊號;比較中頻訊號及目標訊號之頻率差異以產生比較差異結果;根據該比較差異結果產生修正本地訊號;根據接收訊號及修正本地訊號之頻率差異輸出修正中頻訊號以及當該修正中頻訊號與目標訊號間之頻率相等時,鎖定修正中頻訊號。此外,訊號還原方法另外包含根據修正中頻訊號所屬之形態進行解調變並藉此取得修正中頻訊號所包含之資料。
Illuminating the Diversity of Aromatic Polyketide Synthases in Aspergillus nidulans
(2012-05-16)
Ahuja, Manmeet
;
Chiang, Yi-Ming
;
Chang, Shu-Lin
;
Praseuth, Mike B.
;
Entwistle, Ruth
Genome sequencing has revealed that fungi have the ability to synthesize many more natural products (NPs) than are currently known, but methods for obtaining suitable expression of NPs have been inadequate. We have developed a successful strategy that bypasses normal regulatory mechanisms. By efficient gene targeting, we have replaced, en masse, the promoters of nonreducing polyketide synthase (NR-PKS) genes, key genes in NP biosynthetic pathways, and other genes necessary for NR-PKS product formation or release. This has allowed us to determine the products of eight NR-PKSs of Aspergillus nidulans, including seven novel compounds, as well as the NR-PKS genes required for the synthesis of the toxins alternariol (8) and cichorine (19).
有機光電薄膜元件之製造方法
(2012-05-16)
陳方中
;
莊名凱
本發明揭露一種有機光電薄膜元件之製造方法,包含下列步驟:提供一基板及一第一電極;形成一半導體層於該基板上,其中該半導體層包含一聚乙二醇分子;形成一導電高分子層於該第一電極上;將該基板與該半導體層放置至該導電高分子層上,並使該半導體層與該導電高分子層貼附;移除該基板;以及形成一第二電極於該半導體層上,以形成該有機光電薄膜元件。該半導體層與該基板間具有一第一黏著力,該半導體層與該導電高分子層具有一第二黏著力,該第二黏著力大於該第一黏著力,使得當移除該基板時,該半導體層仍會黏貼於該導電高分子層上。
液體介電泳裝置
(2012-05-16)
范士岡
;
盧怡蓓
本發明提供一種液體介電泳裝置，包含：一第一承載單元，界定出一第一承載微空間，並具有一電極組合用以在該第一承載微空間內產生一第一電場；一第二承載單元，界定出一第二承載微空間，並具有一電極組合用以在該第二承載微空間內產生一第二電場；以及一流體通道單元，具有一中間電極區。該中間電極區具有一第一擴大端部、一第二擴大端部、及一連接該第一擴大端部與該第二擴大端部的中間段。本發明也提供一種利用一介電泳裝置輸送液體的方法。
金屬氧化物薄膜電晶體結構及其製造方法
(2012-05-16)
冉曉雯
;
蔡娟娟
;
陳蔚宗
;
薛琇文
一種金屬氧化物薄膜電晶體結構,包含:一閘極;一設於該閘極上的介電層;一設於該介電層上之主動層;分別設於該主動層上相間隔之一源極與一汲極;以及一臨界電壓調製層,其係直接接觸於該電晶體結構的背通道,該臨界電壓調製層與該主動層具有功函數差。藉此,本發明係使用功函數差進行元件之臨界電壓的調製。
氮化鎵電晶體的製作方法
(2012-05-16)
張翼
;
張嘉華
;
林岳欽
本發明提供一種氮化鎵電晶體的製作方法,包含一準備步驟、一開口形成步驟、一離子佈値步驟、一介電層形成步驟、一源/汲極沉積步驟,及一閘極沉積步驟,首先準備一含N型氮化鎵系半導體材料的半導體磊晶層,於該半導體磊晶層上形成一定義出一開口的遮覆層,接著對該半導體磊晶層進行P型離子佈値,於該半導體磊晶層形成一摻雜區,再於該半導體磊晶層表面沉積一層由高介電常數材料構成的介電層,之後於該半導體磊晶層表面對應該摻雜區兩側形成一源極及一汲極,再於對應該摻雜區上方的介電層表面形成一閘極,即可完成該氮化鎵電晶體的製作。
Biomechanical comparison of unilateral and bilateral pedicle screws fixation for transforaminal lumbar interbody fusion after decompressive surgery - a finite element analysis
(2012-05-16)
Chen, Shih-Hao
;
Lin, Shang-Chih
;
Tsai, Wen-Chi
;
Wang, Chih-Wei
;
Chao, Shih-Heng
Background: Little is known about the biomechanical effectiveness of transforaminal lumbar interbody fusion (TLIF) cages in different positioning and various posterior implants used after decompressive surgery. The use of the various implants will induce the kinematic and mechanical changes in range of motion (ROM) and stresses at the surgical and adjacent segments. Unilateral pedicle screw with or without supplementary facet screw fixation in the minimally invasive TLIF procedure has not been ascertained to provide adequate stability without the need to expose on the contralateral side. This study used finite element (FE) models to investigate biomechanical differences in ROM and stress on the neighboring structures after TLIF cages insertion in conjunction with posterior fixation. Methods: A validated finite-element (FE) model of L1-S1 was established to implant three types of cages (TLIF with a single moon-shaped cage in the anterior or middle portion of vertebral bodies, and TLIF with a left diagonally placed ogival-shaped cage) from the left L4-5 level after unilateral decompressive surgery. Further, the effects of unilateral versus bilateral pedicle screw fixation (UPSF vs. BPSF) in each TLIF cage model was compared to analyze parameters, including stresses and ROM on the neighboring annulus, cage-vertebral interface and pedicle screws. Results: All the TLIF cages positioned with BPSF showed similar ROM (<5%) at surgical and adjacent levels, except TLIF with an anterior cage in flexion (61% lower) and TLIF with a left diagonal cage in left lateral bending (33% lower) at surgical level. On the other hand, the TLIF cage models with left UPSF showed varying changes of ROM and annulus stress in extension, right lateral bending and right axial rotation at surgical level. In particular, the TLIF model with a diagonal cage, UPSF, and contralateral facet screw fixation stabilize segmental motion of the surgical level mostly in extension and contralaterally axial rotation. Prominent stress shielded to the contralateral annulus, cage-vertebral interface, and pedicle screw at surgical level. A supplementary facet screw fixation shared stresses around the neighboring tissues and revealed similar ROM and stress patterns to those models with BPSF. Conclusions: TLIF surgery is not favored for asymmetrical positioning of a diagonal cage and UPSF used in contralateral axial rotation or lateral bending. Supplementation of a contralateral facet screw is recommended for the TLIF construct.
建構個人化神經刺激模型之系統及方法
(2012-05-16)
蔡德明
;
李宜軒
一種建構個人化神經刺激模型之系統及方法,首先,量測個人之電生理訊號,且建立具有預設之模型參數的個人化神經刺激模型,其中,該個人化神經刺激模型依據該模型參數產生人體生理參數,接著,分析該模型所產生之人體生理參數並根據參數優化演算法調整該模型之模型參數,俾使該個人化神經刺激模型所輸出之人體生理參數匹配於所量測之該電生理訊號。據此,本發明可實現生物醫學上模擬神經刺激反應之個人化神經刺激模型。