Browsing by Issue Date, starting with "2015-11-16"

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Zebrafish Egg Infection Model for Studying Candida albicans Adhesion Factors
(2015-11-16)
Chen, Yin-Zhi
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Yang, Yun-Liang
;
Chu, Wen-Li
;
You, May-Su
;
Lo, Hsiu-Jung
Disseminated candidiasis is associated with 30-40% mortality in severely immunocompromised patients. Among the causal agents, Candida albicans is the dominant one. Various animal models have been developed for investigating gene functions in C. albicans. Zebrafish injection models have increasingly been applied in elucidating C. albicans pathogenesis because of the conserved immunity, prolific fecundity of the zebrafish and the low costs of care systems. In this study, we established a simple, noninvasive zebrafish egg bath infection model, defined its optimal conditions, and evaluated the model with various C. albicans mutant strains. The deletion of SAP6 did not have significant effect on the virulence. By contrast, the deletion of BCR1, CPH1, EFG1, or TEC1 significantly reduced the virulence under current conditions. Furthermore, all embryos survived when co-incubated with bcr1/bcr1, cph1/cph1 efg1/efg1, efg1/efg1, or tec1/tec1 mutant cells. The results indicated that our novel zebrafish model is time-saving and cost effective.
Optical coherence tomography-guided laser microsurgery for blood coagulation with continuous-wave laser diode
(2015-11-16)
Chang, Feng-Yu
;
Tsai, Meng-Tsan
;
Wang, Zu-Yi
;
Chi, Chun-Kai
;
Lee, Cheng-Kuang
Blood coagulation is the clotting and subsequent dissolution of the clot following repair to the damaged tissue. However, inducing blood coagulation is difficult for some patients with homeostasis dysfunction or during surgery. In this study, we proposed a method to develop an integrated system that combines optical coherence tomography (OCT) and laser microsurgery for blood coagulation. Also, an algorithm for positioning of the treatment location from OCT images was developed. With OCT scanning, 2D/3D OCT images and angiography of tissue can be obtained simultaneously, enabling to noninvasively reconstruct the morphological and microvascular structures for real-time monitoring of changes in biological tissues during laser microsurgery. Instead of high-cost pulsed lasers, continuous-wave laser diodes (CW-LDs) with the central wavelengths of 450 nm and 532 nm are used for blood coagulation, corresponding to higher absorption coefficients of oxyhemoglobin and deoxyhemoglobin. Experimental results showed that the location of laser exposure can be accurately controlled with the proposed approach of imaging-based feedback positioning. Moreover, blood coagulation can be efficiently induced by CW-LDs and the coagulation process can be monitored in real-time with OCT. This technology enables to potentially provide accurate positioning for laser microsurgery and control the laser exposure to avoid extra damage by real-time OCT imaging.
Spiral surface plasmon modes inside metallic nanoholes
(2015-11-16)
Chen, Chih-Min
;
Ke, Jian-Liang
;
Lan, Yung-Chiang
;
Chan, Ming-Che
;
光電學院
Spiral surface plasmon (SSP) modes that propagate inside a silver (Ag) nanohole are investigated by performing both simulations and theoretical analyses. The SSP modes are formed by a linear combination of two rotating SP eigenmodes of the Ag nanohole in the fast-wave branch. Inside a uniform Ag nanohole, the handedness and the number of strands of the SSP modes are determined by both the component SP eigenmodes and their rotation directions. The spiral pitch of the SSP mode increases with the nanohole radius for a fixed wavelength and is inversely related to the incident wavelength for a fixed nanohole radius. Inside a tapered Ag nanohole, the spiral pitch decreases with the reduction of nanohole radius. However, the azimuth-integrated field energy density increases to a maximum value and then falls. For a tapered Ag-clad fiber capped by a tapered Ag nanorod, the SSP mode reverses its handedness when it passes through the fiber-nanorod interface. Furthermore, using this composite structure, the field energy density of SSP mode that arrives at the tip of the tapered nanorod is largely increased. (C) 2015 Optical Society of America
Metal induced crystallized poly-Si-based conductive bridge resistive switching memory device with one transistor and one resistor architecture
(2015-11-16)
Chand, Umesh
;
Huang, Chun-Yang
;
Kumar, Dayanand
;
Tseng, Tseung-Yuen
;
電子工程學系及電子研究所
In this letter, the metal induced crystallization (MIC) process is used in the Si-based conductive bridging resistive random access memory (CBRAM) application. The amorphous Si (a-Si) is transformed to crystallized poly-silicon (poly-Si) at a low temperature by using Ni metal for inducing poly-Si to provide the resistive switching. The MIC process can produce a highly preferred orientation poly-Si film, which can create the exact paths or grain boundaries through the top and down electrodes in the present CBRAM device. The grain boundary in MIC poly-Si layer can confine the conductive filament of metal bridging growth in it, which can improve the switching fluctuation behavior in the nonvolatile memory application. Compared with the a-Si based device, a significant improvement in terms of resistive switching parameters such as stability and resistance distribution is demonstrated in the MIC poly-Si CBRAM device. Moreover, the well-behaved memory performance, such as high ON/OFF resistance ratio (4 order), a large AC endurance (10(6)), and good retention characteristics (10(4) s at 125 degrees C) are achieved in the Cu/poly-Si/n(+)-Si CMOS compatible cross bar structure. (c) 2015 AIP Publishing LLC.
Plasmonic Gold Nanorods Coverage Influence on Enhancement of the Photoluminescence of Two-Dimensional MoS2 Monolayer
(2015-11-17)
Lee, Kevin C. J.
;
Chen, Yi-Huan
;
Lin, Hsiang-Yu
;
Cheng, Chia-Chin
;
Chen, Pei-Ying
The 2-D transition metal dichalcogenide (TMD) semiconductors, has received great attention due to its excellent optical and electronic properties and potential applications in field-effect transistors, light emitting and sensing devices. Recently surface plasmon enhanced photoluminescence (PL) of the weak 2-D TMD atomic layers was developed to realize the potential optoelectronic devices. However, we noticed that the enhancement would not increase monotonically with increasing of metal plasmonic objects and the emission drop after the certain coverage. This study presents the optimized PL enhancement of a monolayer MoS2 in the presence of gold (Au) nanorods. A localized surface plasmon wave of Au nanorods that generated around the monolayer MoS2 can provide resonance wavelength overlapping with that of the MoS2 gain spectrum. These spatial and spectral overlapping between the localized surface plasmon polariton waves and that from MoS2 emission drastically enhanced the light emission from the MoS2 monolayer. We gave a simple model and physical interpretations to explain the phenomena. The plasmonic Au nanostructures approach provides a valuable avenue to enhancing the emitting efficiency of the 2-D nano-materials and their devices for the future optoelectronic devices and systems.
Selective interlayer ferromagnetic coupling between the Cu spins in YBa2Cu3O7-x grown on top of La0.7Ca0.3MnO3
(2015-11-17)
Huang, S. W.
;
Wray, L. Andrew
;
Jeng, Horng-Tay
;
Tra, V. T.
;
Lee, J. M.
Studies to date on ferromagnet/d-wave superconductor heterostructures focus mainly on the effects at or near the interfaces while the response of bulk properties to heterostructuring is overlooked. Here we use resonant soft x-ray scattering spectroscopy to reveal a novel c-axis ferromagnetic coupling between the in-plane Cu spins in YBa2Cu3O7-x (YBCO) superconductor when it is grown on top of ferromagnetic La0.7Ca0.3MnO3 (LCMO) manganite layer. This coupling, present in both normal and superconducting states of YBCO, is sensitive to the interfacial termination such that it is only observed in bilayers with MnO2 but not with La0.7Ca0.3O interfacial termination. Such contrasting behaviors, we propose, are due to distinct energetic of CuO chain and CuO2 plane at the La0.7Ca0.3O and MnO2 terminated interfaces respectively, therefore influencing the transfer of spin-polarized electrons from manganite to cuprate differently. Our findings suggest that the superconducting/ferromagnetic bilayers with proper interfacial engineering can be good candidates for searching the theorized Fulde-Ferrel-Larkin-Ovchinnikov (FFLO) state in cuprates and studying the competing quantum orders in highly correlated electron systems.
Calculation of anharmonic effects in the unimolecular dissociation of M2+ (H2O)(2) (M = Be, Mg, and Ca)
(2015-11-17)
Li, Qian
;
Yao, Li
;
Xia, Wenwen
;
Lin, S. H.
;
應用化學系
The anharmonic and harmonic rate constants of the unimolecular dissociation of M2+(H2O)(2) (M = Be, Mg, and Ca) were calculated using the Rice-Ramsperger-Kassel-Marcus theory. The anharmonic effects of the reactions were investigated. The results show that the energy barrier of the dissociation of Be2+(H2O)(2) is 68.47 kcal/mol, and the anharmonic (T-4000K = 4.28x10(8) s(-1)) and harmonic (T-4000K = 4.22x10(8) s(-1)) rate constants were close in value in both the canonical and microcanonical systems. The energy barriers of the two steps for the dissociation, Mg2+(H2O)(2) MgOH++H3O+, were 37.41 and 11.39 kcal/mol, and those for the dissociation, Ca2+(H2O)(2) CaOH++H3O+, were 21.15 and 26.42 kcal/mol. The anharmonic effect of the two reactions is significant and cannot be neglected in both the canonical and microcanonical systems. The comparison also shows that the rate constants of the dissociation of Ca2+(H2O)(2) have the maximum values, while those of Be2+(H2O)(2) have the minimum values in the three reactions; however, the anharmonic effect also shows the similar trend in the comparison.
Simultaneous Infrared Detection of the ICH2OO Radical and Criegee Intermediate CH2OO: The Pressure Dependence of the Yield of CH2OO in the Reaction CH2I + O-2
(2015-11-19)
Huang, Yu-Hsuan
;
Chen, Li-Wei
;
Lee, Yuan-Pern
;
應用化學系
;
應用化學系分子科學碩博班
The simplest Criegee intermediate CH2OO, important in atmospheric reactions, has been recently produced from the reaction of CH2I + O-2 and detected with various methods. In this reaction, the yield of CH2OO decreases with increasing pressure because of the stabilization of the adduct ICH2OO, but no definitive spectral identification of ICH2OO has been reported. We recorded the infrared spectrum of ICH2OO using the same reaction under high pressure; the spectrum agrees with that simulated according to theoretical predictions. With direct detection of both CH2OO and ICH2OO, we determined the pressure dependence of the yield of CH2OO. The yield of CH2OO near 1 atm is greater than previously reported values, which might have significant consequences in atmospheric chemistry.
OPTICAL AID AND RETINAL IMPLANT DEVICE THEREOF
(2015-11-19)
Wu Chung-Yu
;
Lin Po-Kang
;
Chiao Chuan-Chin
;
Pan Jui-Wen
An optical aid comprises a projecting device and a retinal implant device. The projecting device includes an image projector for outputting a projected image and a light generator for emitting an auxiliary light that differs in wavelength from the projected image. The retinal implant device includes an optical-to-electrical converter and an image sensor. The optical-to-electrical converter converts the auxiliary light received thereby into electricity for powering the image sensor. The image sensor is disposed in such a way that the auxiliary light is not received thereby, and generates an electrical stimulus signal associated with the projected image.
PHARMACEUTICAL COMPOSITION AND USE FOR APPLYING 7,7''-DIMETHOXYAGASTISFLAVONE IN INHIBITING TUMOR METASTASIS
(2015-11-19)
LIAO Kuang-Wen
;
LIN Ching-Min
;
LIN Yu-Ling
A pharmaceutical composition for inhibiting tumor metastasis is disclosed. The pharmaceutical composition includes a therapeutically effective amount of 7,7″-Dimethoxyagastisflavone (DMGF) and a pharmaceutically acceptable carrier. The present invention also discloses a use of DMGF for manufacturing a pharmaceutical composition applied to inhibit tumor metastasis. The application of the pharmaceutical composition and the use of the present invention are advantageous for inhibiting tumor metastasis efficiently.
Linear solubilizing side chain substituents enhance the photovoltaic properties of two-dimensional conjugated benzodithiophene-based polymers
(2015-11-19)
Jiang, Jian-Ming
;
Raghunath, Putikam
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Lin, Yu-Che
;
Lin, Hsi-Kuei
;
Ko, Chen-Lin
In this study we synthesized medium-band gap, two-dimensional (2-D) conjugated polymers comprising electron-rich benzo[1,2-b:4,5-b\'] dithiophene (BDT) units presenting conjugated thiophene (T) side chains and electron-deficient alkoxy-modified 2,1,3-benzooxadiazole (BO) moieties. We introduced various solubilizing substituents-linear alkyl, alkoxy, and alkythio units-on the thiophene side chains to obtain a series of 2-D conjugated D-pi-A polymers: PBDTT-C-BO, PBDTT-O-BO, and PBDTT-S-BO. The solubilizing substituents of the BDT units altered the solubility, conformations, and electronic properties of the synthesized conjugated polymers, allowing tuning of the photovoltaic properties when blended with fullerenes. We investigated the effects of the different linear solubilizing substituents of the BDT units on the structural, optical, and electronic properties (e.g., band gap energies) of the resulting 2-D conjugated polymers, as determined from quantum-chemical calculations, UV-Vis absorption spectra, and grazing-incidence X-ray diffraction. Atomic force microscopy and transmission electron microscopy images revealed the morphologies of active layers comprising these 2-D conjugated polymers and the fullerene derivative [6,6]-phenyl-C-71-butyric acid methyl ester (PC71BM). Through rational structural modifications of the solubilizing substituents in the 2-D conjugated polymers with alkoxy, alkythio or alkyl units, the resulting PCEs varied from 5.4 to 7.5%. A polymer solar cell based on a blend of PBDTT-C-BO and PC71BM exhibited the best photovoltaic performance among our three studied systems, with a high short-circuit current density (J(sc)) of 15.7 mA cm(-2) and a power conversion efficiency of 7.5%, without the need for any processing additives or post-treatment processes, highlighting the importance of careful selection of appropriate solubilizing substituent that attached to the donor segments when designing efficient D-pi-A polymers for use in solar cells. (C) 2015 Elsevier Ltd. All rights reserved.
交大e-News第198期-成功研發先進駕駛輔助系統業界紛來取經
(2015-11-20)
國立交通大學秘書室
;
Secretariat
General Homologation Strategy for Synthesis of L-glycero- and D-glycero-Heptopyranoses
(2015-11-20)
Mulani, Shaheen K.
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Cheng, Kuang-Chun
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Mong, Kwok-Kong T.
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應用化學系
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Department of Applied Chemistry
A general and stereospecific homologation strategy for the synthesis of heptopyranosides is reported. The strategy employs the Wittig olefination and proline-catalyzed a-aminoxylation to achieve one carbon elongation and stereoselective hydroxylation at the C6 position, respectively. The l-glycero- and d-glycero-heptopyranosides can be obtained with nearly perfect stereoselectivity. Further study reveals the difference in the chemical shift of the C6 proton of l/d-glycero-heptopyranosyl diastereomers, which is found to be useful for assignment of the configuration of heptopyranosides.
基於髖部資訊之行動感應裝置
(2015-11-21)
謝一弘
;
洪偉鐘
;
楊谷洋
;
柯春旭
一種基於髖部資訊之行動感應裝置，包括：一行動輔具；一超音波測距模組，設於該行動輔具上，該超音波測距模組包含一透明殼體及至少三超音波感測器，水平間隔設於該透明殼體中，係連續偵測一使用者之髖關節的位置與該行動輔具之間的相對距離；及一微處理器，設於該行動輔具，且電性連接該超音波測距模組，該微處理器根據該相對距離計算出該髖關節的旋轉角度及該使用者行走意圖，並根據該使用者行走意圖對應控制該行動輔具移動。
超大型電晶體陣列式電氣參數測試裝置
(2015-11-21)
洪浩喬
一種超大型電晶體陣列式電氣參數測試裝置，包含：一測試晶胞陣列，其係包含複數測試晶胞，每一該測試晶胞更包含：一待測場效電晶體，其係接收一第一設定電壓、一閘極電壓與一基極設定電壓；以及一控制場效電晶體，其以其源極疊接(Cascode)該待測場效電晶體；以及一控制驅動電路，連接該些測試晶胞之該控制場效電晶體之閘極與該些測試晶胞之該控制場效電晶體之汲極，並接收一第二設定電壓與一閘極設定電壓，該控制驅動電路接收複數第一數位訊號與複數第二數位訊號，以據此依序選擇每一該測試晶胞作為待測晶胞，該控制驅動電路傳送該閘極設定電壓至該待測晶胞之該待測場效電晶體作為該待測場效電晶體之該閘極電壓，該待測晶胞之該待測場效電晶體依據該閘極設定電壓、該第一設定電壓與該基極設定電壓以產生一輸出電流，該控制驅動電路透過該待測晶胞之該控制場效電晶體之該汲極接收並量測該輸出電流，並根據該輸出電流與該第二設定電壓產生一控制電壓作為該待測晶胞之該控制場效電晶體之閘極電壓，進而形成一閉回路以準確設定該待測晶胞之該控制場效電晶體之源極電壓，藉此準確量測該待測晶胞之該待測場效電晶體之電氣參數。
用於無線傳輸環境中的影像傳輸方法
(2015-11-21)
林烜立
;
吳東祐
;
余恭賢
;
黃經堯
一種降低一影像失真率的影像傳輸方法，包括：提供一無線傳輸環境；偵測一延遲上限保證及一影像訊框錯誤率；檢測一封包錯誤率以提供一判讀結果；以及根據該判讀結果、該延遲上限保證及該影像訊框錯誤率，當判斷需重新傳輸時，以一幾何規劃演算法計算一全區域性最佳解。
鉑奈米粒子溶液及自組裝鉑對電極之製備方法
(2015-11-21)
刁維光
;
蔡佳宏
;
李陸玲
;
吳忻蕙
一種鉑奈米粒子溶液之製備方法，包含下列步驟：提供一六氯鉑酸乙二醇溶液；及將該六氯鉑酸乙二醇溶液升溫至100~120℃，進行迴流反應2~5小時，並以一氫氧化鈉溶液調控該六氯鉑酸乙二醇溶液之pH值於2.7~4.9之間，即製得該鉑奈米粒子溶液。
白光發光二極體封裝結構的製造方法
(2015-11-21)
王興宗
;
郭浩中
;
陳信助
;
陳國儒
一種具有氧化物膠層之白光發光二極體封裝結構的製造方法，至少包含：提供一基板；提供一發光二極體晶片，設置該發光二極體晶片於該基板上，使得在該基板及在該發光二極體晶片之上形成一容置空間，其中設置該發光二極體晶片在該基板上的方法，包括：一打線接合(wire bonding)技術；以及一覆晶晶片(flip chip)結合技術；執行一封裝製程，係於該容置空間內填入一封裝材料以包覆該發光二極體晶片、該導線及該基板以形成一封裝結構，其封裝材料係由矽膠(silicon)以及環氧樹脂(epoxy)群組中所選出；利用一噴塗法形成一螢光粉層在該封裝結構之一表面上，其中該螢光粉層的厚度約為100μm；以及形成一氧化物膠層在該螢光粉層上，包含：提供一氧化物奈米粒子；以及混合該氧化物奈米粒子與一矽膠層，其中該氧化物奈米粒子係由氧化鋯、氧化鋁(AlO2 )、氧化鈦(TiO2 )以及二氧化矽(SiO2 )群組中所選出，該氧化物膠層內之該氧化物奈米粒子及該矽膠層的濃度比為5%：95%。
金屬板材測試系統及其測試方法
(2015-11-21)
洪景華
;
陳彥佑
;
蔡宇中
一種金屬板材測試系統，用以整合一金屬板材之複數種機械性質的測試，該系統至少包含：一夾持裝置，具有一第一模具、一第二模具與一超彈體墊片，其中該第一模具與該第二模具間可夾持對應於一金屬板材之一試片組中的任一者，且該超彈體墊片係可拆地設置於該試片組中之該任一者與該第二模具間；一液壓裝置，連接該夾持裝置，並經由該第二模具提供一液壓於該試片組中之該任一者以使其朝向該第一模具的方向膨脹；以及一量測裝置，分別連接該夾持裝置與該液壓裝置以即時量測該液壓之一瞬間壓力與該試片組中之該任一者之一膨脹高度，其中該量測裝置包含：一第一感測器；以及一第二感測器，當該第一模具與該第二模具夾持該試片，且該液壓裝置持續提供該液壓於該試片時，該第一感測器用以量測該試片之一膨脹高度，該第二感測器連接該第二模具以量測該液壓之一瞬間壓力，該量測裝置係根據該膨脹高度與該瞬間壓力計算出一第一數據。
即時多通道自動眼動雜訊去除器
(2015-11-21)
方偉騏
;
廖瑞傑
;
石偉業
;
黃冠儒
;
陳秋國
一種即時多通道自動眼動雜訊去除器，係包括：接收單元，係用於接收一通道中之獨立成分資料，該獨立成分資料係紀錄有一時間區段中的腦波訊號；暫存單元，係用於暫存該接收單元所接收之多筆獨立成分資料，該多筆獨立成分資料係依據時間區段先後形成一資料段；偵測單元，係用於透過取樣熵演算法對該資料段進行眼動雜訊的偵測，以產生對應該時間區段下之該資料段的取樣熵值；以及處理單元，係用於依據該取樣熵值判定該資料段是否含有眼動雜訊以產生一結果資料，其中，該處理單元若判斷該資料段中含有該眼動雜訊一半以上之波形者，則判定該資料段含有該眼動雜訊，且依據該結果資料進行眼動雜訊去除，並輸出代表該筆資料段之已處理獨立成分資料，其中，該接收單元持續接收次一筆獨立成分資料，且該暫存單元拋棄該資料段中最舊一筆該獨立成分資料並加入新一筆該獨立成分資料以形成新的資料段，該新的資料段由該偵測單元和該處理單元進行偵測及判斷，藉以持續對每一筆資料段執行該眼動雜訊的去除動作。