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收集所有交通大學研究人員與學生個人或團體所發表之各項學術著作，涵蓋期刊論文、教師專書、學位論文等項。;;Collections of Publications of NCTU Researchers and Students Like Journal Papers and Thesis.

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Author: search.filters.author.Lai, Kelvin Yi-TseSubject: search.filters.subject.Biochip

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    An Intelligent Digital Microfluidic Processor for Biomedical Detection
    (2015-01-01)
    Lai, Kelvin Yi-Tse
    ;
    Yang, Yu-Tao
    ;
    Lee, Chen-Yi
    ;
    電子工程學系及電子研究所
    ;
    Department of Electronics Engineering and Institute of Electronics
    An intelligent digital microfluidic processor for biomedical detection is presented. This potential architecture solves lots of traditional development bottlenecks to implement the easy-to-control, easy-to-monitor, system automation and high accuracy for bioassay detection purposes. The proposed processor integrates the functions of microfluidic actuation, droplet location readback and high sensitivity measurement window to demonstrate a novel prototype for personalized medicine. Furthermore, the droplet location map and reaction behaviors are visible on a 2-dimentional (2D) graphical user-interface due to the micro electrode dot array (MEDA) architecture and capacitive sensing technology, and hence system automation is achievable. Fabricated in standard 0.35 mu m CMOS process, this work integrates 900 microelectrodes with measurement window in 3.2 mm(2), where the high sensitivity capacitive readout circuit occupies only 0.048 mm(2). Measurement results show that microdroplet actuation and 2D location map are activated under 1KHz. In addition, the function of digital signal extraction, processing, as well as statistical analysis can be operated under 1 MHz respectively.
  • Thumbnail Image
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    A DIGITAL MICROFLUIDIC PROCESSOR FOR BIOMEDICAL APPLICATIONS
    (2013)
    Lai, Kelvin Yi-Tse
    ;
    Yang, Yu-Tao
    ;
    Wang, Gary
    ;
    Lu, Yi-Wen
    ;
    Lee, Chen-Yi
    A digital microfluidic processor for biomedical detection is presented. This processor integrates the functions of droplet actuation, droplet position/shape/volume detection and capacitive measurement window to demonstrate a novel prototype for personalize medicine. In this proposed system, the location map of microdroplets and reaction behaviors are visible on 2-dimentional (2D) graphical user-interface due to capacitive sensing technology and hence automatic signal processing is achievable. Fabricated in standard 0.35um 2P4M CMOS process, this test chip integrates 900 microelectrodes with measurement window in 3.2mm(2). Measurement results show that operation of microdroplet moving is under 1KHz and digital signal extractions of position detection and statistical analysis are under 1MHz respectively.