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Item type:Item, Three-Dimensional Printed Porous Titanium Screw with Bioactive Surface Modification for Bone-Tendon Healing: A Rabbit Animal Model(2020-05-01) ;Huang, Yu-Min ;Huang, Chih-Chieh ;Tsai, Pei-I ;Yang, Kuo-YiHuang, Shin-IThe interference screw fixation method is used to secure a graft in the tibial tunnel during anterior cruciate ligament reconstruction surgery. However, several complications have been reported, such as biodegradable screw breakage, inflammatory or foreign body reaction, tunnel enlargement, and delayed graft healing. Using additive manufacturing (AM) technology, we developed a titanium alloy (Ti6Al4V) interference screw with chemically calcium phosphate surface modification technology to improve bone integration in the tibial tunnel. After chemical and heat treatment, the titanium screw formed a dense apatite layer on the metal surface in simulated body fluid. Twenty-seven New Zealand white rabbits were randomly divided into control and additive manufactured (AMD) screw groups. The long digital extensor tendon was detached and translated into a tibial plateau tunnel (diameter: 2.0 mm) and transfixed with an interference screw while the paw was in dorsiflexion. Biomechanical analyses, histological analyses, and an imaging study were performed at 1, 3, and 6 months. The biomechanical test showed that the ultimate pull-out load failure was significantly higher in the AMD screw group in all tested periods. Micro-computed tomography analyses revealed early woven bone formation in the AMD screw group at 1 and 3 months. In conclusion, AMD screws with bioactive surface modification improved bone ingrowth and enhanced biomechanical performance in a rabbit model.Item type:Item, 3D-printed microelectronics for integrated circuitry and passive wireless sensors(2015-01-01) ;Wu, Sung-Yueh ;Yang, Chen ;Hsu, Wensyang ;Lin, Liwei機械工程學系Three-dimensional (3D) additive manufacturing techniques have been utilized to make 3D electrical components, such as resistors, capacitors, and inductors, as well as circuits and passive wireless sensors. Using the fused deposition modeling technology and a multiple-nozzle system with a printing resolution of 30 mu m, 3D structures with both supporting and sacrificial structures are constructed. After removing the sacrificial materials, suspensions with silver particles are injected subsequently solidified to form metallic elements/interconnects. The prototype results show good characteristics of fabricated 3D microelectronics components, including an inductor-capacitor-resonant tank circuitry with a resonance frequency at 0.53 GHz. A 3D "smart cap" with an embedded inductor-capacitor tank as the wireless passive sensor was demonstrated to monitor the quality of liquid food (e.g., milk and juice) wirelessly. The result shows a 4.3% resonance frequency shift from milk stored in the room temperature environment for 36 h. This work establishes an innovative approach to construct arbitrary 3D systems with embedded electrical structures as integrated circuitry for various applications, including the demonstrated passive wireless sensors.Item type:Item, Improvement of bone-tendon fixation by porous titanium interference screw: A rabbit animal model(2018-10-01) ;Tsai, Pei-I ;Chen, Chih-Yu ;Huang, Shu-Wei ;Yang, Kuo-YiLin, Tzu-HungThe interference screw is a widely used fixation device in the anterior cruciate ligament (ACL) reconstruction surgeries. Despite the generally satisfactory results, problems of using interference screws were reported. By using additive manufacturing (AM) technology, we developed an innovative titanium alloy (Ti6Al4V) interference screw with rough surface and inter-connected porous structure designs to improve the bone-tendon fixation. An innovative Ti6Al4V interference screws were manufactured by AM technology. In vitro mechanical tests were performed to validate its mechanical properties. Twenty-seven New Zealand white rabbits were randomly divided into control and AM screw groups for biomechanical analyses and histological analysis at 4, 8, and 12 weeks postoperatively; while micro-CT analysis was performed at 12 weeks postoperatively. The biomechanical tests showed that the ultimate failure load in the AM interference screw group was significantly higher than that in the control group at all tested periods. These results were also compatible with the findings of micro-CT and histological analyses. In micro-CT analysis, the bone-screw gap was larger in the control group; while for the additive manufactured screw, the screw and bone growth was in close contact. In histological study, the bone-screw gaps were wider in the control group and were almost invisible in the AM screw group. The innovative AM interference screws with surface roughness and inter-connected porous architectures demonstrated better bone-tendon-implant integration, and resulted in stronger biomechanical characteristics when compared to traditional screws. These advantages can be transferred to future interference screw designs to improve their clinical performance. The AM interference screw could improve graft fixation and eventually result in better biomechanical performance of the bone-tendon-screw construct. The innovative AM interference screws can be transferred to future interference screw designs to improve the performance of implants. (c) 2018 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:2633-2640, 2018.Item type:Item, Application of Ultrafast Laser Nanostructuring to Selective Laser Melting Parts(2015-12) ;Cheng, Chung-Wei ;Chien, Chih-Wei ;Lin, De-Yau ;Horng, Ji-Bin機械工程學系A method is proposed for the fabrication of 3D metal (Ti6AL4V) parts that have microstructures covered with controllable nanostructures using selective laser melting (SLM) followed by laser-induced periodic surface structures (LIPSS). The metallic parts with microstructures was first fabricated by the SLM process, then a ultrafast laser machining platform was used to locally nanostructuring of the metal parts by LIPSS process. The experimental results show that periodic-like nanostructures with two different periods, i.e. 800-900 nm on the top surface and 450-600 nm on the bottom surface of the SLM-produced microstructures, were obtained simultaneously by a picosecond laser at wavelength 1064 mu with the same laser irradiation parameters. The liquid test demonstrates that the SLM+LIPSS process provides a structuring method to generate hydrophobic-enhanced metal parts. The process can provide a variety of 3D hierarchical micro/nanostructuring on metal material for biomedical application (e.g. customized implants) which is more than a conventional SLM process can provide.Item type:Item, RF WIRELESS LC TANK SENSORS FABRICATED BY 3D ADDITIVE MANUFACTURING(2015) ;Wu, Sung-Yueh ;Yang, Chen ;Hsu, Wensyang ;Lin, Liwei交大名義發表We present wireless inductor-capacitor (LC) tank sensors constructed by the three-dimensional (3D) additive manufacturing technique. Fabricated 3D structures with hollow channels are filled with liquid metal (silver particles) to form basic electrical components including inductors and capacitors. In the prototype design, a radio-frequency (RF) LC tank with resonance frequency at 0.53 GHz is realized. This LC tank sensor is utilized in rapid detection of liquid food (e.g., milk and juice). Specifically, the resonant frequency of the LC tank changes as the dielectric constant of the liquid food deteriorates over time and the signals are detected via an inductively coupled reader wirelessly. In the preliminary tests, a 4.3% frequency shift for milk stored at room temperature after 36 hours was obtained. This work presents a new class of manufacturing concepts to construct arbitrary 3D electrical systems for wireless sensing applications.Item type:Item, Application of Ultrafast Laser Nanostructuring to Selective Laser Melting Parts(2015-12-01) ;Cheng, Chung-Wei ;Chien, Chih-Wei ;Lin, De-Yau ;Horng, Ji-Bin機械工程學系A method is proposed for the fabrication of 3D metal (Ti6AL4V) parts that have microstructures covered with controllable nanostructures using selective laser melting (SLM) followed by laser-induced periodic surface structures (LIPSS). The metallic parts with microstructures was first fabricated by the SLM process, then a ultrafast laser machining platform was used to locally nanostructuring of the metal parts by LIPSS process. The experimental results show that periodic-like nanostructures with two different periods, i.e. 800-900 nm on the top surface and 450-600 nm on the bottom surface of the SLM-produced microstructures, were obtained simultaneously by a picosecond laser at wavelength 1064 mu with the same laser irradiation parameters. The liquid test demonstrates that the SLM+LIPSS process provides a structuring method to generate hydrophobic-enhanced metal parts. The process can provide a variety of 3D hierarchical micro/nanostructuring on metal material for biomedical application (e.g. customized implants) which is more than a conventional SLM process can provide.