MO(CO)(6)-mediated synthesis of calix[4]arenes carrying beta-hydroxy ketones or alpha,beta-unsaturated-beta-amino ketones

Abstract

MO(CO)(6)-mediated ring opening reactions of calix[4]arene isoxazolines/isoxazoles provide a new synthetic methodology for calix[4]arenes carrying bifunctional beta-hydroxy ketones or alpha,beta-unsaturated-beta-amino ketones. MO(CO)(6) is a highly selective and convenient reagent for the ring opening process of these supramolecular isoxazolines/isoxazoles. (c) 2006 Elsevier Ltd. All rights reserved.