Measuring the flexibility of immunoglobulin by gold nanoparticles

doi:10.1021/nl061598x

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DC 欄位	值	語言
dc.contributor.author	Huang, G. Steven	en_US
dc.contributor.author	Chen, Yu-Shiun	en_US
dc.contributor.author	Yeh, Hsiao-Wei	en_US
dc.date.accessioned	2014-12-08T15:15:23Z	-
dc.date.available	2014-12-08T15:15:23Z	-
dc.date.issued	2006-11-08	en_US
dc.identifier.issn	1530-6984	en_US
dc.identifier.uri	http://dx.doi.org/10.1021/nl061598x	en_US
dc.identifier.uri	http://hdl.handle.net/11536/11555	-
dc.description.abstract	We measured the flexibility of Fab and Fc arms of immunoglobulin using gold nanoparticles (GNPs). Enzyme-linked immunosorbent assay was performed to measure the affinity of anti-5 nm GNP antiserum against various sizes of GNPs. The flexibility of Fc was also measured by electron microscopy. The restricted binding affinity indicated that only a very limited amount of freedom was allowed for the Fab-Fab hinge, while Fab-Fc showed a much larger degree of freedom.	en_US
dc.language.iso	en_US	en_US
dc.title	Measuring the flexibility of immunoglobulin by gold nanoparticles	en_US
dc.type	Article	en_US
dc.identifier.doi	10.1021/nl061598x	en_US
dc.identifier.journal	NANO LETTERS	en_US
dc.citation.volume	6	en_US
dc.citation.issue	11	en_US
dc.citation.spage	2467	en_US
dc.citation.epage	2471	en_US
dc.contributor.department	材料科學與工程學系奈米科技碩博班	zh_TW
dc.contributor.department	奈米科技中心	zh_TW
dc.contributor.department	Graduate Program of Nanotechnology , Department of Materials Science and Engineering	en_US
dc.contributor.department	Center for Nanoscience and Technology	en_US
dc.identifier.wosnumber	WOS:000241856700014	-
dc.citation.woscount	21	-
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