完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chang, YR | en_US |
dc.contributor.author | Hsu, L | en_US |
dc.contributor.author | Chi, S | en_US |
dc.date.accessioned | 2014-12-08T15:16:28Z | - |
dc.date.available | 2014-12-08T15:16:28Z | - |
dc.date.issued | 2006-06-01 | en_US |
dc.identifier.issn | 0003-6935 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1364/AO.45.003885 | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/12187 | - |
dc.description.abstract | Since their invention in 1986, optical tweezers have become a popular manipulation and force measurement tool in cellular and molecular biology. However, until recently there has not been a sophisticated model for optical tweezers on trapping cells in the ray-optics regime. We present a model for optical tweezers to calculate the optical force upon a spherically symmetric multilayer sphere representing a common biological cell. A numerical simulation of this model shows that not only is the magnitude of the optical force upon a Chinese hamster ovary cell significantly three times smaller than that upon a polystyrene bead of the same size, but the distribution of the optical force upon a cell is also much different from that upon a uniform particle, and there is a 30% difference in the optical trapping stiffness of these two cases. Furthermore, under a small variant condition for the refractive indices of any adjacent layers of the sphere, this model provides a simple approximation to calculate the optical force and the stiffness of an optical tweezers system. (c) 2006 Optical Society of America. | en_US |
dc.language.iso | en_US | en_US |
dc.title | Optical trapping of a spherically symmetric sphere in the ray-optics regime: a model for optical tweezers upon cells | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1364/AO.45.003885 | en_US |
dc.identifier.journal | APPLIED OPTICS | en_US |
dc.citation.volume | 45 | en_US |
dc.citation.issue | 16 | en_US |
dc.citation.spage | 3885 | en_US |
dc.citation.epage | 3892 | en_US |
dc.contributor.department | 電子物理學系 | zh_TW |
dc.contributor.department | 光電工程學系 | zh_TW |
dc.contributor.department | Department of Electrophysics | en_US |
dc.contributor.department | Department of Photonics | en_US |
dc.identifier.wosnumber | WOS:000237863800032 | - |
dc.citation.woscount | 19 | - |
顯示於類別: | 期刊論文 |