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dc.contributor.authorWang Yun-Mingen_US
dc.contributor.authorLiu Gin-Chungen_US
dc.contributor.authorChen Chiao-Yunen_US
dc.contributor.authorLi Teng-Wenen_US
dc.date.accessioned2015-05-12T02:59:37Z-
dc.date.available2015-05-12T02:59:37Z-
dc.date.issued2015-02-24en_US
dc.identifier.govdocA61K051/00zh_TW
dc.identifier.govdocA61K049/00zh_TW
dc.identifier.govdocA61B005/00zh_TW
dc.identifier.govdocA61K038/04zh_TW
dc.identifier.urihttp://hdl.handle.net/11536/122816-
dc.description.abstractA ligand and a metal complex having the ligand are provided. The ligand and a paramagnetic metal ion form a metal complex with high stability, high relaxivity and high biocompatibility. The metal complex of the present invention is applicable to the preparation of MRI contrast agents for detecting atherosclerosis. The MRI contrast agent includes a peptide sequence specific to a matrix metalloprotease, and can be recognized by a pathological thrombocyte to target a specific site, so as to enhance the imaging contrast.zh_TW
dc.language.isozh_TWen_US
dc.titleLigand and metal complex having the samezh_TW
dc.typePatentsen_US
dc.citation.patentcountryUSAzh_TW
dc.citation.patentnumber08961928zh_TW
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