Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Deng, Jie-Cheng | en_US |
dc.contributor.author | Chuang, Shih-Ching | en_US |
dc.date.accessioned | 2015-07-21T08:28:28Z | - |
dc.date.available | 2015-07-21T08:28:28Z | - |
dc.date.issued | 2014-11-07 | en_US |
dc.identifier.issn | 1523-7060 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1021/ol502879c | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/123911 | - |
dc.description.abstract | Multicomponent reactions of phosphines, diynedioates, and aryl aldehydes have been demonstrated, providing trisubstituted furans appending reactive phosphorus ylides, through cumulated trienoates as key intermediates. The proposed trienoate intermediates, 1,5-dipolar species formed via nucleophilic alpha-attack of phosphines toward diynedioates (alpha-addition-delta-evolvement of an anion, abbreviated alpha A delta E), undergo addition to aryl aldehydes followed by 5-endo-dig cyclization, proton transfer, and resonance to give trisubstituted furans. Furthermore, the phosphorus ylides are oxidized to alpha-keto ester furans and utilized as Wittig reagents. | en_US |
dc.language.iso | en_US | en_US |
dc.title | Multicomponent Reactions of Phosphines, Diynedioates, and Aryl Aldehydes Generated Furans Appending Reactive Phosphorus Ylides through Cumulated Trienoates as Key Intermediates: A Phosphine alpha-Addition-delta-Evolvement of an Anion Pathway | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1021/ol502879c | en_US |
dc.identifier.journal | ORGANIC LETTERS | en_US |
dc.citation.volume | 16 | en_US |
dc.citation.issue | 21 | en_US |
dc.citation.spage | 5792 | en_US |
dc.citation.epage | 5795 | en_US |
dc.contributor.department | 應用化學系 | zh_TW |
dc.contributor.department | Department of Applied Chemistry | en_US |
dc.identifier.wosnumber | WOS:000344635200073 | en_US |
dc.citation.woscount | 1 | en_US |
Appears in Collections: | Articles |