完整後設資料紀錄
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dc.contributor.authorHsieh, Yi-Hanen_US
dc.contributor.authorLiu, Kuang-Kaien_US
dc.contributor.authorSulake, Rohidas S.en_US
dc.contributor.authorChao, Jui-I.en_US
dc.contributor.authorChen, Chinpiaoen_US
dc.date.accessioned2015-07-21T08:29:47Z-
dc.date.available2015-07-21T08:29:47Z-
dc.date.issued2015-05-15en_US
dc.identifier.issn0960-894Xen_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.bmcl.2015.03.089en_US
dc.identifier.urihttp://hdl.handle.net/11536/124640-
dc.description.abstractNanodiamond has recently received considerable attention due to the various possible applications in medical field such as drug delivery and bio-labeling. For this purpose suitable and effective surface functionalization of the diamond material are required. A versatile and reproducible surface modification method of nanoscale diamond is essential for functionalization. We introduce the input of microwave energy to assist the functionalization of nanodiamond surface. The feasibility of such a process is illustrated by comparing the biological assay of ND-paclitaxel synthesized by conventional and microwave irradiating. Using a microwave we manage to have approximately doubled grafted molecules per nanoparticle of nanodiamond. (C) 2015 Elsevier Ltd. All rights reserved.en_US
dc.language.isoen_USen_US
dc.subjectNanodiamonden_US
dc.subjectPaclitaxelen_US
dc.subjectMicrowave irradiatingen_US
dc.subjectDeaggregationen_US
dc.subjectLung canceren_US
dc.titleMicrowave-assisted efficient conjugation of nanodiamond and paclitaxelen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.bmcl.2015.03.089en_US
dc.identifier.journalBIOORGANIC & MEDICINAL CHEMISTRY LETTERSen_US
dc.citation.volume25en_US
dc.citation.issue10en_US
dc.citation.spage2074en_US
dc.citation.epage2077en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.identifier.wosnumberWOS:000353526300012en_US
dc.citation.woscount0en_US
顯示於類別:期刊論文