完整後設資料紀錄
DC 欄位語言
dc.contributor.authorLiu, Kun-Hoen_US
dc.contributor.authorLiu, Ting-Yuen_US
dc.contributor.authorLiu, Dean-Moen_US
dc.contributor.authorChen, San-Yuanen_US
dc.date.accessioned2014-12-08T15:17:32Z-
dc.date.available2014-12-08T15:17:32Z-
dc.date.issued2009-02-01en_US
dc.identifier.issn1533-4880en_US
dc.identifier.urihttp://dx.doi.org/10.1166/jnn.2009.C119en_US
dc.identifier.urihttp://hdl.handle.net/11536/12723-
dc.description.abstractIn the present study, the nanoparticles with size of 50-130 nm composed of chitosan (CS) and tetraethyl orthosilicate (TEOS), which showed electrically-control led release profile, were prepared. Myoglobin was encapsulated into the nanoparticles with an encapsulation efficiency as high as 91.5% and a maximum loading capacity of 70.2% that can be achieved. Here, TEOS was hydrolyzed and condensed to form interpenetration network with CS. Increase of TEOS content results in a shift of the release profile from swelling-controlled towards diffusion-controlled mechanism. The "slow-to-burst" and "near-zero" release of the myoglobin can be effectively controlled by applying DC electric field between "on" and "off."en_US
dc.language.isoen_USen_US
dc.subjectPolyelectrolyteen_US
dc.subjectElectric-Stimulien_US
dc.subjectNanoparticleen_US
dc.titleElectrical-Sensitive Nanoparticle Composed of Chitosan and Tetraethyl Orthosilicate for Controlled Drug Releaseen_US
dc.typeArticle; Proceedings Paperen_US
dc.identifier.doi10.1166/jnn.2009.C119en_US
dc.identifier.journalJOURNAL OF NANOSCIENCE AND NANOTECHNOLOGYen_US
dc.citation.volume9en_US
dc.citation.issue2en_US
dc.citation.spage1198en_US
dc.citation.epage1203en_US
dc.contributor.department材料科學與工程學系zh_TW
dc.contributor.departmentDepartment of Materials Science and Engineeringen_US
dc.identifier.wosnumberWOS:000263653300119-
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