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dc.contributor.authorSingh, Gyanen_US
dc.contributor.authorHsu, Kuang-Meien_US
dc.contributor.authorChen, Yu-Jenen_US
dc.contributor.authorWu, Shou-Chengen_US
dc.contributor.authorChen, Chiao-Yunen_US
dc.contributor.authorWang, Yun-Mingen_US
dc.date.accessioned2015-12-02T02:59:22Z-
dc.date.available2015-12-02T02:59:22Z-
dc.date.issued2015-01-01en_US
dc.identifier.issn1359-7345en_US
dc.identifier.urihttp://dx.doi.org/10.1039/c5cc01723hen_US
dc.identifier.urihttp://hdl.handle.net/11536/128106-
dc.description.abstractThis communication presents the first Gd(III)-based T-1 MRI contrast agent, o-MeHgGad, for noninvasive visualization of CH3Hg+. o-MeHgGad showed a relaxivity enhancement of 62% in the presence of 1 equiv. of CH3Hg+. Moreover, a noticeable contrast enhancement was recorded in the liver, kidney, and intestine of mice exposed to CH3Hg+. Thus, the newly designed contrast agent has the potential to be used for in vivo bio-imaging of CH3Hg+ and could be useful for biomedical applications.en_US
dc.language.isoen_USen_US
dc.titleA switch-on MRI contrast agent for noninvasive visualization of methylmercuryen_US
dc.typeArticleen_US
dc.identifier.doi10.1039/c5cc01723hen_US
dc.identifier.journalCHEMICAL COMMUNICATIONSen_US
dc.citation.volume51en_US
dc.citation.issue60en_US
dc.citation.spage12032en_US
dc.citation.epage12035en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.identifier.wosnumberWOS:000357951400022en_US
dc.citation.woscount0en_US
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