標題: | Functionalized graphene nanocomposites for enhancing photothermal therapy in tumor treatment |
作者: | Chen, Yu-Wei Su, Yu-Lin Hu, Shang-Hsiu Chen, San-Yuan 材料科學與工程學系 Department of Materials Science and Engineering |
關鍵字: | Graphene;Photothermal therapy;Composites;Drug delivery;Tumor therapy |
公開日期: | 1-十月-2016 |
摘要: | Graphene and its derivatives have unique physical and chemical properties that make them promising vehicles for photothermal therapy (PTT)-based cancer treatment. With intrinsic near-infrared (NIR) absorption properties, graphene-based nanomaterials can be used for PTT and other therapeutics, particularly in combination therapy, to provide successful thermal ablation of cancer cells. In the recent years, advances in graphene-based PTT have produced efficient and efficacious tumor inhibition via nanomaterial structural design and different functionalizations of graphene-derived nanocomposites. Graphene-based nanosystems exhibit multifunctional properties that are useful for PTT applications including enhancement of multimodalities, guided imaging, enhanced chemotherapy and low-power efficient PTT for optimum therapeutic efficiency. Therefore, in this review, we address critical issues and future aspects of PTT-based combination therapy. (C) 2016 Elsevier B.V. All rights reserved. |
URI: | http://dx.doi.org/10.1016/j.addr.2016.05.022 http://hdl.handle.net/11536/132653 |
ISSN: | 0169-409X |
DOI: | 10.1016/j.addr.2016.05.022 |
期刊: | ADVANCED DRUG DELIVERY REVIEWS |
Volume: | 105 |
起始頁: | 190 |
結束頁: | 204 |
顯示於類別: | 期刊論文 |