標題: Carbon-Based Materials for Photo-Triggered Theranostic Applications
作者: Albert, Karunya
Hsu, Hsin-Yun
應用化學系
應用化學系分子科學碩博班
Department of Applied Chemistry
Institute of Molecular science
關鍵字: carbon materials;nanomedicine;photosensitizer;near infrared-triggered agents;photodynamic therapy
公開日期: 十一月-2016
摘要: Carbon-based nanomaterials serve as a type of smart material for photo-triggered disease theranostics. The inherent physicochemical properties of these nanomaterials facilitate their use for less invasive treatments. This review summarizes the properties and applications of materials including fullerene, nanotubes, nanohorns, nanodots and nanographenes for photodynamic nanomedicine in cancer and antimicrobial therapies. Carbon nanomaterials themselves do not usually act as photodynamic therapy (PDT) agents owing to the high hydrophobicity, however, when the surface is passivated or functionalized, these materials become great vehicles for PDT. Moreover, conjugation of carbonaceous nanomaterials with the photosensitizer (PS) and relevant targeting ligands enhances properties such as selectivity, stability, and high quantum yield, making them readily available for versatile biomedical applications.
URI: http://dx.doi.org/10.3390/molecules21111585
http://hdl.handle.net/11536/132833
ISSN: 1420-3049
DOI: 10.3390/molecules21111585
期刊: MOLECULES
Volume: 21
Issue: 11
顯示於類別:期刊論文