標題: Calix[4]arenes with Combined Axial Chirality and Inherent Chirality: Synthesis, Absolute Configuration and Chiral Recognition
作者: Zhang, Wen-Zhen
Ma, Hui
Xiang, Guang-Ya
Luo, Jun
Chung, Wen-Sheng
應用化學系
Department of Applied Chemistry
關鍵字: Supramolecular chemistry;Calixarenes;Chirality;Diastereoselectivity;Molecular recognition
公開日期: 1-Jul-2016
摘要: Calix[4]arene diastereomeric pairs with combined axial chirality and inherent chirality were readily synthesized via monoalkylation of 1,2-substituted calix[4]arene crown-4 incorporating an axially chiral binaphthyl moiety with different electrophiles as a key step. The reaction showed high generality and distinct diastereoselectivity. The easy separation of the diaster-eomers, the good diastereoselectivity of the reaction, and the poor stereoselectivity of the chiral recognition of diastereomeric pairs were attributed to the remarkable steric effect of the axially chiral binaphthyl moiety. Absolute configurations were determined by X-ray crystallography.
URI: http://dx.doi.org/10.1002/slct.201600709
http://hdl.handle.net/11536/133365
ISSN: 2365-6549
DOI: 10.1002/slct.201600709
期刊: CHEMISTRYSELECT
Volume: 1
Issue: 10
起始頁: 2486
結束頁: 2491
Appears in Collections:Articles