标题: | Calix[4]arenes with Combined Axial Chirality and Inherent Chirality: Synthesis, Absolute Configuration and Chiral Recognition |
作者: | Zhang, Wen-Zhen Ma, Hui Xiang, Guang-Ya Luo, Jun Chung, Wen-Sheng 应用化学系 Department of Applied Chemistry |
关键字: | Supramolecular chemistry;Calixarenes;Chirality;Diastereoselectivity;Molecular recognition |
公开日期: | 1-七月-2016 |
摘要: | Calix[4]arene diastereomeric pairs with combined axial chirality and inherent chirality were readily synthesized via monoalkylation of 1,2-substituted calix[4]arene crown-4 incorporating an axially chiral binaphthyl moiety with different electrophiles as a key step. The reaction showed high generality and distinct diastereoselectivity. The easy separation of the diaster-eomers, the good diastereoselectivity of the reaction, and the poor stereoselectivity of the chiral recognition of diastereomeric pairs were attributed to the remarkable steric effect of the axially chiral binaphthyl moiety. Absolute configurations were determined by X-ray crystallography. |
URI: | http://dx.doi.org/10.1002/slct.201600709 http://hdl.handle.net/11536/133365 |
ISSN: | 2365-6549 |
DOI: | 10.1002/slct.201600709 |
期刊: | CHEMISTRYSELECT |
Volume: | 1 |
Issue: | 10 |
起始页: | 2486 |
结束页: | 2491 |
显示于类别: | Articles |