標題: | Photonic crystal micropost as a microarray platform |
作者: | Chang, Chih-Wei Huang, Cheng-Sheng 機械工程學系 Department of Mechanical Engineering |
公開日期: | 8-二月-2016 |
摘要: | This study demonstrates a photonic crystal micropost (PCMP) substrate for microarray applications. The substrate comprises an array of circular MPs with a PC on top of these MPs. This substrate enables biomolecule-containing droplets to form a composite contact upon deposition, thus allowing biomolecules to be attached on only the MPs, forming spots. When the device (PC) is excited on resonance, the electric field intensity is enhanced on only the top surface of the MPs. This enables the fluorescence intensities to be enhanced up to 5.50x; principally, this enhancement does not engender an increase in the background (intensity outside MP or spots) and noise intensities. The PCMP substrate enhances the spot intensity and minimizes the background intensity, enabling the detection of lower concentration analytes. (C) 2016 Optical Society of America |
URI: | http://dx.doi.org/10.1364/OE.24.002954 http://hdl.handle.net/11536/133527 |
ISSN: | 1094-4087 |
DOI: | 10.1364/OE.24.002954 |
期刊: | OPTICS EXPRESS |
Volume: | 24 |
Issue: | 3 |
起始頁: | 2954 |
結束頁: | 2964 |
顯示於類別: | 期刊論文 |