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dc.contributor.authorLiu, Ta-Chungen_US
dc.contributor.authorChu, Chao-Yien_US
dc.contributor.authorChen, You-Yinen_US
dc.contributor.authorChen, San-Yuanen_US
dc.date.accessioned2019-04-03T06:42:14Z-
dc.date.available2019-04-03T06:42:14Z-
dc.date.issued2016-01-01en_US
dc.identifier.issn2046-2069en_US
dc.identifier.urihttp://dx.doi.org/10.1039/c6ra01016den_US
dc.identifier.urihttp://hdl.handle.net/11536/133572-
dc.description.abstractIn this study, a facile one-step Cyclic Voltammetry (CV) electrophoresis was proposed for designing a reduced graphene oxide/gold oxide (rGO/AuOx) modified electrode by using chloride ions (Cl-) with the simultaneous occurrence of gold oxidation and GO reduction to induce the intimate attachment of negatively charged rGO sheets on the positively charged Au+/Au3+ clusters by electrostatic interaction. The surface microstructure and the oxygen functional groups of rGO/AuOx can be tuned by controlling the dissolution rate of gold via the deposition scan rate. At a low deposition scan rate, the rGO/AuOx electrode with well-dispersive rGO sheets and large active sites can induce rapid electron transfer to promote H2O2 detection. The amperometric response results displayed a relative fast response of less than 5 s with a low detection limit of 0.63 mu M (S/N = 3). Also, the rGO/AuOx neural-chemical interface can be modified at the multi-channels on neural probe and they exhibited excellent sensing performance to H2O2. The results demonstrated that the rGO/AuOx modified electrode integrated with a neural probe using this one-step electrochemical deposition can provide a faster response and higher sensitivity by optimizing and controlling the surface microstructures of rGO/AuOx, which would serve as a platform for medical application such as biosensors for multi-sensing.en_US
dc.language.isoen_USen_US
dc.titleNewly reduced graphene oxide/gold oxide neural-chemical interface on multi-channel neural probes to enhance the electrochemical properties for biosensorsen_US
dc.typeArticleen_US
dc.identifier.doi10.1039/c6ra01016den_US
dc.identifier.journalRSC ADVANCESen_US
dc.citation.volume6en_US
dc.citation.issue33en_US
dc.citation.spage27614en_US
dc.citation.epage27622en_US
dc.contributor.department材料科學與工程學系zh_TW
dc.contributor.departmentDepartment of Materials Science and Engineeringen_US
dc.identifier.wosnumberWOS:000372644100041en_US
dc.citation.woscount1en_US
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