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dc.contributor.authorDalvi, Prashant B.en_US
dc.contributor.authorLin, Kuang-Lingen_US
dc.contributor.authorKulkarni, Manohar V.en_US
dc.contributor.authorSun, Chung-Mingen_US
dc.date.accessioned2017-04-21T06:55:33Z-
dc.date.available2017-04-21T06:55:33Z-
dc.date.issued2016-08-05en_US
dc.identifier.issn1523-7060en_US
dc.identifier.urihttp://dx.doi.org/10.1021/acs.orglett.6b01408en_US
dc.identifier.urihttp://hdl.handle.net/11536/134095-
dc.description.abstractAn unprecedented two-step, one-pot synthesis of benzimidazothiadiazine 5,5-dioxides is presented. Reaction condition based regioselectivity has been achieved where fused benzimidazo[1,2-b][1,2,4]thiadiazines are exclusively formed under thermal conditions, whereas benzimidazo[2,1-c][1,2,4]thiadiazines were created only under microwave irradiation. The salient features of this protocol include a regioselective sulfonylation of 2-aminobenzimidazole with o-halo sulfonyl chlorides followed by N-C bond formation. The acid forms of these fused regioisomers have been used to introduce novel guanidine containing isocoumarin frameworks.en_US
dc.language.isoen_USen_US
dc.titleRhodium-Catalyzed Regioselective Synthesis of Isocoumarins through Benzothiadiazine-Fused Frameworksen_US
dc.identifier.doi10.1021/acs.orglett.6b01408en_US
dc.identifier.journalORGANIC LETTERSen_US
dc.citation.volume18en_US
dc.citation.issue15en_US
dc.citation.spage3706en_US
dc.citation.epage3709en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000381236300050en_US
Appears in Collections:Articles