標題: | Synthesis and biological evaluation of novel angularly fused polycyclic coumarins |
作者: | Khan, IA Kulkarni, MV Gopal, M Shahabuddin, MS Sun, CM 應用化學系 Department of Applied Chemistry |
公開日期: | 1-八月-2005 |
摘要: | In a three-step sequence, an array of angularly fused polycyclic heterocycles with coumarin, benzofuran and pyridine rings were synthesized from 4-bromomethylcoumarins and salicylonitrile. All the final compounds were fully characterized and screened for anti-microbial, anti-inflammatory and analgesic activities. Several compounds exhibited promising inflammation inhibiting and anti-microbial properties. (c) 2005 Elsevier Ltd. All rights reserved. |
URI: | http://dx.doi.org/10.1016/j.bmcl.2005.05.063 http://hdl.handle.net/11536/13449 |
ISSN: | 0960-894X |
DOI: | 10.1016/j.bmcl.2005.05.063 |
期刊: | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS |
Volume: | 15 |
Issue: | 15 |
起始頁: | 3584 |
結束頁: | 3587 |
顯示於類別: | 期刊論文 |