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dc.contributor.authorLu, Hui-Hisnen_US
dc.contributor.authorLin, Chii-Wannen_US
dc.contributor.authorFang, Yueh-Yuanen_US
dc.contributor.authorHsiao, Tzu-Chienen_US
dc.contributor.authorHsu, Su-Mingen_US
dc.date.accessioned2017-04-21T06:49:32Z-
dc.date.available2017-04-21T06:49:32Z-
dc.date.issued2009en_US
dc.identifier.isbn978-3-540-89207-6en_US
dc.identifier.issn1680-0737en_US
dc.identifier.urihttp://hdl.handle.net/11536/134971-
dc.description.abstractThis study presents an imaging technique combining multi-functional dark field microscopy (DFM) with spectroscopy to image the nanostructures of different formats of optical disks and identify their optical properties by absorption spectra. The resolution of this DFM system is determined using one-dimension nanostructure with lengths from 160 nm to 600 nm. The pattern sizes are confirmed by atomic force microscopy (AFM). The results show that DFM resolution is about 160 nm with the current setup, and the resulting DFM image size appears to be slightly larger than a AFM image. We then deposited a 50 nm gold film on top of these nanostructures and measured their absorption spectra to identify the relationship between surface plasmon resonance (SPR) spectra and one-dimensional nanostructures. The immobilization of streptavidin on the surface of the gold-coated nanostructure causes changes in the absorption spectrum ranging from 450nm to 650nm.en_US
dc.language.isoen_USen_US
dc.subjectone-dimensional nanostrustureen_US
dc.subjectsurface Plasmonen_US
dc.subjectdark field microscopyen_US
dc.titleMonitoring Biomolecular Interaction with 1-D Plasmonic Nanostructure by Using Dark Field Microscopyen_US
dc.typeProceedings Paperen_US
dc.identifier.journal4TH EUROPEAN CONFERENCE OF THE INTERNATIONAL FEDERATION FOR MEDICAL AND BIOLOGICAL ENGINEERINGen_US
dc.citation.volume22en_US
dc.citation.issue1-3en_US
dc.citation.spage2300en_US
dc.citation.epage2303en_US
dc.contributor.department分子醫學與生物工程研究所zh_TW
dc.contributor.departmentInstitute of Molecular Medicine and Bioengineeringen_US
dc.identifier.wosnumberWOS:000299998500552en_US
dc.citation.woscount0en_US
Appears in Collections:Conferences Paper