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dc.contributor.authorChen, CYen_US
dc.contributor.authorChen, SLen_US
dc.contributor.authorChristensen, ERen_US
dc.date.accessioned2014-12-08T15:19:13Z-
dc.date.available2014-12-08T15:19:13Z-
dc.date.issued2005-05-01en_US
dc.identifier.issn0730-7268en_US
dc.identifier.urihttp://dx.doi.org/10.1897/04-147R.1en_US
dc.identifier.urihttp://hdl.handle.net/11536/13764-
dc.description.abstractA closed- system algal toxicity test with no headspace was applied to evaluate the toxicity of I I aldehydes and two nitrites to Raphidocelis subcapitata. Algal growth rate and dissolved oxygen (DO) production were used as the test endpoints. Compared to literature data, our test results based on the endpoint of DO production is 2.5 to 257 times more sensitive than the conventional algal batch tests. In addition, our analyses show that different relative toxicity relationships may be observed when different test methods or different endpoints are applied. The test alga was found to be quite sensitive to aldehydes, and a quantitative structure- activity relationship (QSAR) relationship was established based on the n-octanol/water partition coefficient (log K,,.). This study also evaluated the combined effects of aldehydes and nitriles. Four synergistic joint actions related to majononitrile were identified. On the other hand, most of the combined effects between aldehydes and acetonitrile were antagonistic. In general, we find that greater-than-additive effects mainly are associated with toxicants displaying flat dose-response curves, and less-than-additive effects may be related to certain steep-slope chemicals. Model analyses show that the above mixture toxicity behavior may be due to response addition or response multiplication joint action modes.en_US
dc.language.isoen_USen_US
dc.subjectalgaeen_US
dc.subjectRaphidocelis subcapitataen_US
dc.subjectmedian lethal concentrationen_US
dc.subjectaldehydeen_US
dc.subjectmixture toxicityen_US
dc.titleIndividual and combined toxicity of nitriles and aldehydes to Raphidocelis subcapitataen_US
dc.typeArticleen_US
dc.identifier.doi10.1897/04-147R.1en_US
dc.identifier.journalENVIRONMENTAL TOXICOLOGY AND CHEMISTRYen_US
dc.citation.volume24en_US
dc.citation.issue5en_US
dc.citation.spage1067en_US
dc.citation.epage1073en_US
dc.contributor.department環境工程研究所zh_TW
dc.contributor.departmentInstitute of Environmental Engineeringen_US
dc.identifier.wosnumberWOS:000228627100008-
dc.citation.woscount17-
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