抗NMDA受體腦炎的病程管制圖

Abstract

抗NMDA受體腦炎（anti-NMDA receptor encephalitis）是一種近年來新發現的急性腦炎，其初始症狀類似精神疾病而後有癲癇和運動障礙等等症狀，許多女性患者會檢查出現畸形瘤（Teratoma）。本篇論文目的為嘗試使用統計手法，得以監控此疾病其患者，在各時間點其疾病的嚴重程度，以達到改善病患療程目的。本篇論文收集了79篇醫學文獻中的病例報告，將其有提及之重要部分，如各症狀發生之時間，量化成可使用的資料並分析，找出合適且有用之部分，再以品質管制七大手法中的管制圖（Control chart）的概念，建立以週為單位之管制界線。

Anti-NMDA receptor encephalitis is a recently-found acute encephalitis. Its initial symptoms were similar to mental illness, and later comes up with dyskinesia and other symptoms. Many female patients would be examined with Teratoma. The purpose of this thesis is to monitor the patients with this disease by using statistic method, and to improve the treatment for patient by monitoring patients’ illness level in different time. The thesis collected the case reports in 79 medical essays, quantified the important part that they mentioned—such as the time that each symptom appears—into usable data, found out the suitable part, and establish the control limits in weeks with the concept of Control chart.