完整後設資料紀錄
DC 欄位語言
dc.contributor.authorChou, Chih-Hungen_US
dc.contributor.authorShrestha, Sirjanaen_US
dc.contributor.authorYang, Chi-Dungen_US
dc.contributor.authorChang, Nai-Wenen_US
dc.contributor.authorLin, Yu-Lingen_US
dc.contributor.authorLiao, Kuang-Wenen_US
dc.contributor.authorHuang, Wei-Chien_US
dc.contributor.authorSun, Ting-Hsuanen_US
dc.contributor.authorTu, Siang-Jyunen_US
dc.contributor.authorLee, Wei-Hsiangen_US
dc.contributor.authorChiew, Men-Yeeen_US
dc.contributor.authorTai, Chun-Sanen_US
dc.contributor.authorWei, Ting-Yenen_US
dc.contributor.authorTsai, Tzi-Renen_US
dc.contributor.authorHuang, Hsin-Tzuen_US
dc.contributor.authorWang, Chung-Yuen_US
dc.contributor.authorWu, Hsin-Yien_US
dc.contributor.authorHo, Shu-Yien_US
dc.contributor.authorChen, Pin-Rongen_US
dc.contributor.authorChuang, Cheng-Hsunen_US
dc.contributor.authorHsieh, Pei-Jungen_US
dc.contributor.authorWu, Yi-Shinen_US
dc.contributor.authorChen, Wen-Liangen_US
dc.contributor.authorLi, Meng-Juen_US
dc.contributor.authorWu, Yu-Chunen_US
dc.contributor.authorHuang, Xin-Yien_US
dc.contributor.authorNg, Fung Lingen_US
dc.contributor.authorBuddhakosai, Waradeeen_US
dc.contributor.authorHuang, Pei-Chunen_US
dc.contributor.authorLan, Kuan-Chunen_US
dc.contributor.authorHuang, Chia-Yenen_US
dc.contributor.authorWeng, Shun-Longen_US
dc.contributor.authorCheng, Yeong-Nanen_US
dc.contributor.authorLiang, Chaoen_US
dc.contributor.authorHsu, Wen-Lianen_US
dc.contributor.authorHuang, Hsien-Daen_US
dc.date.accessioned2018-08-21T05:53:09Z-
dc.date.available2018-08-21T05:53:09Z-
dc.date.issued2018-01-04en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttp://dx.doi.org/10.1093/nar/gkx1067en_US
dc.identifier.urihttp://hdl.handle.net/11536/144338-
dc.description.abstractMicroRNAs (miRNAs) are small non-coding RNAs of similar to 22 nucleotides that are involved in negative regulation of mRNA at the post-transcriptional level. Previously, we developed miRTarBase which provides information about experimentally validated miRNA-target interactions (MTIs). Here, we describe an updated database containing 422 517 curated MTIs from 4076 miRNAs and 23 054 target genes collected from over 8500 articles. The number of MTIs curated by strong evidence has increased similar to 1.4-fold since the last update in 2016. In this updated version, target sites validated by reporter assay that are available in the literature can be downloaded. The target site sequence can extract new features for analysis via a machine learning approach which can help to evaluate the performance of miRNA-target prediction tools. Furthermore, different ways of browsing enhance user browsing specific MTIs. With these improvements, miRTarBase serves as more comprehensively annotated, experimentally validated miRNA-target interactions databases in the field of miRNA related research. miRTarBase is available at http://miRTarBase.mbc.nctu.edu.tw/.en_US
dc.language.isoen_USen_US
dc.titlemiRTarBase update 2018: a resource for experimentally validated microRNA-target interactionsen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/nar/gkx1067en_US
dc.identifier.journalNUCLEIC ACIDS RESEARCHen_US
dc.citation.volume46en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.department生物資訊及系統生物研究所zh_TW
dc.contributor.department分子醫學與生物工程研究所zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.contributor.departmentInstitude of Bioinformatics and Systems Biologyen_US
dc.contributor.departmentInstitute of Molecular Medicine and Bioengineeringen_US
dc.identifier.wosnumberWOS:000419550700045en_US
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