完整後設資料紀錄
DC 欄位 | 值 | 語言 |
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dc.contributor.author | Shellaiah, Muthaiah | en_US |
dc.contributor.author | Simon, Turibius | en_US |
dc.contributor.author | Venkatesan, Parthiban | en_US |
dc.contributor.author | Sun, Kien Wen | en_US |
dc.contributor.author | Ko, Fu-Hsiang | en_US |
dc.contributor.author | Wu, Shu-Pao | en_US |
dc.date.accessioned | 2018-08-21T05:53:11Z | - |
dc.date.available | 2018-08-21T05:53:11Z | - |
dc.date.issued | 2018-01-01 | en_US |
dc.identifier.issn | 0026-3672 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1007/s00604-017-2611-7 | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/144371 | - |
dc.description.abstract | Nanodiamonds were modified such that they carry thiol groups (ND-thiol). Gold nanoparticles were reacted with ND-thiol to obtain a highly stable conjugate of the type ND@AuNPs. Both ND-thiol and the ND@AuNPs were characterized by SEM, TEM, AFM, DLS, zeta potential, XPS, XRD, UV-Vis, Raman, FTIR and cytotoxicity studies. Their biocompatibility was confirmed via an MTT assay with HeLa cells. At a pH value of 6, the ND@AuNPs represent a colorimetric probe that can be used to selectively detect the illegally used beta-adrenergic drug clenbuterol (CLB) and the pollutant chromium(III). Detection can be performed visually by monitoring the color change from wine red to purple blue, or by colorimetric measurement of the so-called SPR peaks at 651 and 710 nm. The color changes are due to aggregation, and this is confirmed by TEM and DLS data. The involvement of surface functional groups that assist in analyte recognition was verified by FTIR. The detection limits are 0.49 nM for CLB, and 0.37 nM for Cr(III). The ND@AuNPs were successfully applied to the determination of Cr(III) and CLB in spiked human urine samples. Notably, the low interference by other ions in the detection of Cr(III) in tap and lake water is confirmed by ICP-MS analyses. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | Gold nanoparticles | en_US |
dc.subject | Nanocomposite | en_US |
dc.subject | beta-Adrenergic drug assay | en_US |
dc.subject | Chromium(III) recognition | en_US |
dc.subject | pH effective sensor | en_US |
dc.subject | Surface plasmon resonance | en_US |
dc.subject | Sub-nanomolar detection | en_US |
dc.subject | Urine analysis | en_US |
dc.subject | Water analysis | en_US |
dc.title | Nanodiamonds conjugated to gold nanoparticles for colorimetric detection of clenbuterol and chromium(III) in urine | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s00604-017-2611-7 | en_US |
dc.identifier.journal | MICROCHIMICA ACTA | en_US |
dc.citation.volume | 185 | en_US |
dc.contributor.department | 材料科學與工程學系 | zh_TW |
dc.contributor.department | 應用化學系 | zh_TW |
dc.contributor.department | 電子工程學系及電子研究所 | zh_TW |
dc.contributor.department | Department of Materials Science and Engineering | en_US |
dc.contributor.department | Department of Applied Chemistry | en_US |
dc.contributor.department | Department of Electronics Engineering and Institute of Electronics | en_US |
dc.identifier.wosnumber | WOS:000422691200006 | en_US |
顯示於類別: | 期刊論文 |