完整後設資料紀錄
DC 欄位語言
dc.contributor.authorBaig, Mirza Muhammad Fahaden_US
dc.contributor.authorChen, Yu-Chieen_US
dc.date.accessioned2018-08-21T05:53:17Z-
dc.date.available2018-08-21T05:53:17Z-
dc.date.issued2018-02-01en_US
dc.identifier.issn1618-2642en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s00216-017-0836-2en_US
dc.identifier.urihttp://hdl.handle.net/11536/144492-
dc.description.abstractDipicolinic acid (DPA) can cause neurotoxicity and is abundant in bacterial spores. Although analytical methods have been reported for DPA detection with high sensitivity, their selectivity toward DPA is declined greatly in the presence of phosphates in the samples. In this study, we developed an approach for DPA detection that is not affected by the presence of phosphates. A colorimetric method based on the use of gold nanoparticles (AuNP) complexed with Ca2+ as sensing agents was explored for DPA detection. Calcium ions and glutathione-capped gold nanoparticles (AuNPs@GSH) can easily form complexes (Ca2+-AuNP@GSH) through GSH-Ca2+ chelation, leading to the aggregation of AuNPs@GSH. The aggregation resulting from the complexes of AuNPs@GSH and Ca2+ can be reversed with the addition of DPA owing to the high formation constant (log K (f) = 4.4) between DPA and Ca2+. Furthermore, the color of AuNPs@GSH changes from red to purple when complexed with Ca2+, returning to red upon addition of DPA. The limit of detection of this sensing method toward DPA was estimated to be as low as similar to 2 mu M. The feasibility of using the sensing method for quantitative detection of DPA in soil and Bacillus cereus spore samples was also demonstrated.en_US
dc.language.isoen_USen_US
dc.subjectGold nanoparticlesen_US
dc.subjectDipicolinic aciden_US
dc.subjectColorimetric sensingen_US
dc.subjectBacterial sporesen_US
dc.titleGold nanoparticle-based colorimetric sensing of dipicolinic acid from complex samplesen_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s00216-017-0836-2en_US
dc.identifier.journalANALYTICAL AND BIOANALYTICAL CHEMISTRYen_US
dc.citation.volume410en_US
dc.citation.spage1805en_US
dc.citation.epage1815en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000424643800018en_US
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