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dc.contributor.authorChung, Chieh-Wenen_US
dc.contributor.authorTsai, May-Jywanen_US
dc.contributor.authorLin, Peng-Weien_US
dc.contributor.authorHuang, Ding-Wenen_US
dc.contributor.authorWang, Kuan-Hsunen_US
dc.contributor.authorChen, Yu-Anen_US
dc.contributor.authorMeng, Hsin-Feien_US
dc.contributor.authorZan, Hsiao-Wenen_US
dc.contributor.authorCheng, Henrichen_US
dc.contributor.authorTong, Liminen_US
dc.contributor.authorZhang, Leien_US
dc.contributor.authorHorng, Sheng-Fuen_US
dc.contributor.authorHung, Cheng-Hsiungen_US
dc.date.accessioned2018-08-21T05:53:23Z-
dc.date.available2018-08-21T05:53:23Z-
dc.date.issued2018-02-01en_US
dc.identifier.issn2158-3226en_US
dc.identifier.urihttp://dx.doi.org/10.1063/1.4994231en_US
dc.identifier.urihttp://hdl.handle.net/11536/144626-
dc.description.abstractA NO sensing tip is made by inserting two parallel optical fibers inside a poly 2-hydroxyethyl methacrylate (PolyHEMA) hydrogel waveguide mixed with the probe molecule 1, 2-Diaminoanthraquinone (DAQ). There is a length difference of 1 mm between the two fibers, and the light has to propagate through the difference from the short fiber to the long fiber. The total cross section area of the active hydrogel waveguide embedded with the fibers is only 3mm x 1.2 mm. For practical use the tip is housed in a needle for mechanical protection and the sensing tip is able to detect aqueous NO concentration around 1 mu M with time resolution about 5 minutes. Such a sensing tip can be used to monitor the medical conditions inside the brain after a stroke or a brain injury. (C) 2018 Author(s).en_US
dc.language.isoen_USen_US
dc.titleAccurate real-time sensing tip for aqueous NO with optical fibers embedded in active hydrogel waveguideen_US
dc.typeArticleen_US
dc.identifier.doi10.1063/1.4994231en_US
dc.identifier.journalAIP ADVANCESen_US
dc.citation.volume8en_US
dc.contributor.department分子醫學與生物工程研究所zh_TW
dc.contributor.department物理研究所zh_TW
dc.contributor.department光電工程學系zh_TW
dc.contributor.departmentInstitute of Molecular Medicine and Bioengineeringen_US
dc.contributor.departmentInstitute of Physicsen_US
dc.contributor.departmentDepartment of Photonicsen_US
dc.identifier.wosnumberWOS:000426580900054en_US
Appears in Collections:Articles