標題: Multi-stimuli-responsive high contrast fluorescence molecular controls with a far-red emitting BODIPY-based [2]rotaxane
作者: Arumugaperumal, Reguram
Venkatesan, Parthiban
Shukla, Tarun
Raghunath, Putikam
Singh, Ravinder
Wu, Shu-Pao
Lin, Ming-Chang
Lin, Hong-Cheu
材料科學與工程學系
應用化學系
Department of Materials Science and Engineering
Department of Applied Chemistry
關鍵字: [2]rotaxane;Molecular motion;BODIPY;H2PO4-;Ion sensor;Semi-empirical PM6 method;Bio-imaging
公開日期: 1-十月-2018
摘要: A novel fluorescent switchable [2]rotaxane NIR4 composed of two different molecular stations and rotaxane arms terminated with far-red boron-dipyrromethene (BODIPY) fluorophores and its derivatives were synthesized by CuAAC click chemistry. The molecular shuttling motion of mechanically interlocked molecules (MIMs) could be addressed by the fluorescence signal transduction via distance dependent photo-induced electron transfer process of [2]rotaxane NIR4 triggered by external chemical stimuli of acid/base. Moreover, the flexible arms of triazolium moiety in [2]rotaxane NIR4 and its axle NIR2 exhibited impressive selectivity and sensitivity toward complementary anionic analyte (H2PO4-), where the specific mechanical molecular motion was supported by quantum mechanical calculations. The development of [2]rotaxane NIR4 with a high level of structural complexity can be utilized for novel dual sensory detections of acid-base and dihydrogen phosphate (H2PO4-) anion. Importantly, the host of NIR2 and [2]rotaxane NIR4 could be applied for the vitro imaging and clarify the distribution of H2PO4- at subcellular levels.
URI: http://dx.doi.org/10.1016/j.snb.2018.05.062
http://hdl.handle.net/11536/145069
ISSN: 0925-4005
DOI: 10.1016/j.snb.2018.05.062
期刊: SENSORS AND ACTUATORS B-CHEMICAL
Volume: 270
起始頁: 382
結束頁: 395
顯示於類別:期刊論文