Full metadata record
DC FieldValueLanguage
dc.contributor.authorChen, Chang-Huaen_US
dc.contributor.authorKuo, Han-Yuehen_US
dc.contributor.authorHsu, Po-Juien_US
dc.contributor.authorChang, Chien-Minen_US
dc.contributor.authorChen, Jiann-Yuanen_US
dc.contributor.authorLu, Henry Horng-Shingen_US
dc.contributor.authorChen, Hsin-Yaoen_US
dc.contributor.authorLiou, Ming-Lien_US
dc.date.accessioned2018-08-21T05:53:44Z-
dc.date.available2018-08-21T05:53:44Z-
dc.date.issued2018-06-01en_US
dc.identifier.issn1684-1182en_US
dc.identifier.urihttp://dx.doi.org/10.1016/j.jmii.2017.08.001en_US
dc.identifier.urihttp://hdl.handle.net/11536/145094-
dc.description.abstractBackground: The global spread of carbapenem-resistant Acinetobacter baumannii (CRAB) is now a public health problem. In Taiwan, the relationship of the CRAB circulation between long-term care facilities (LTCFs) and acute care hospitals remains unclear. Here, we use molecular epidemiologic methods to describe the transmission of CRAB isolates between a community hospital and its affiliated LTCFs. Methods: Subjects localized in eight LTCFs who were not admitted acute care hospitals in recent a year were enrolled in this study. CRAB isolates were collected during June 1, 2015 and December 31, 2015. DNA fingerprinting was performed by repetitive extragenic palindromic sequence-based polymerase chain reaction (Rep-PCR) and multilocus sequence typing (MLST). Multiplex-PCR amplification for the detection of bla(OXA) genes and beta-lactamase genes was performed. Results: Twenty one subjects were enrolled. The major hospital admission diagnoses among the 21 subjects were pneumonia (71.4%). Genotyping of CRAB isolates by Rep-PCR revealed that a major clone, designated as type III, comprised fifteen of 21 (71.4%) isolates taken from 5 LTCFs and one study hospital. The isolates with type III were subtyped by PubMLST into 4 ST types. The most prevalent bla(OXA) genes in these isolates were bla(OXA-23)-like (85.70%, 18/21). Twenty isolates carried bla(SHV). Conclusion: Clonal spread of bla(OXA-23)-carrying CRABs was found around LTCFs and the affiliated hospital. In Taiwan, it is important for the government to focus attention on the importance of identifying and tracing CRAB infections in LTCFs. Copyright (C) 2017, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC.en_US
dc.language.isoen_USen_US
dc.subjectCarbapenem-resistant Acinetobacter baumanniien_US
dc.subjectA community hospitalen_US
dc.subjectLong-term care facilitiesen_US
dc.titleClonal spread of carbapenem-resistant Acinetobacter baumannii across a community hospital and its affiliated long-term care facilities: A cross sectional studyen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.jmii.2017.08.001en_US
dc.identifier.journalJOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTIONen_US
dc.citation.volume51en_US
dc.citation.spage377en_US
dc.citation.epage384en_US
dc.contributor.department統計學研究所zh_TW
dc.contributor.departmentInstitute of Statisticsen_US
dc.identifier.wosnumberWOS:000434423800011en_US
Appears in Collections:Articles