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dc.contributor.authorHovhannisyan, Vladimiren_US
dc.contributor.authorDong, Chen-Yuanen_US
dc.contributor.authorChen, Shean-Jenen_US
dc.date.accessioned2019-04-03T06:35:57Z-
dc.date.available2019-04-03T06:35:57Z-
dc.date.issued2017-03-31en_US
dc.identifier.issn2045-2322en_US
dc.identifier.urihttp://dx.doi.org/10.1038/srep45503en_US
dc.identifier.urihttp://hdl.handle.net/11536/145293-
dc.description.abstractClinoptilolite type of zeolite (CZ) is a promising material for biomedicine and pharmaceutics due to its non-toxicity, thermal stability, expanded surface area, and exceptional ability to adsorb various atoms and organic molecules into micropores. Using multiphoton microscopy, we demonstrated that individual CZ particles produce two-photon excited luminescence and second harmonic generation signal at femtosecond laser excitation, and adsorb photo-dynamically active dyes such as hypericin and methylene blue. Furthermore, the release of hypericin from CZ pores in the presence of biomolecules is shown, and CZ can be considered as an effective material for drug delivery and controlled release in biological systems. The results may open new perspectives in application of CZ in biomedical imaging, and introducing of the optical approaches into the clinical environment.en_US
dc.language.isoen_USen_US
dc.titlePhotodynamic dye adsorption and release performance of natural zeoliteen_US
dc.typeArticleen_US
dc.identifier.doi10.1038/srep45503en_US
dc.identifier.journalSCIENTIFIC REPORTSen_US
dc.citation.volume7en_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department光電學院zh_TW
dc.contributor.departmentCollege of Photonicsen_US
dc.identifier.wosnumberWOS:000397884400002en_US
dc.citation.woscount2en_US
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