標題: A triple action chemosensor for Cu2+ by chromogenic, Cr3+ by fluorogenic and CN- by relay recognition methods with bio-imaging of HeLa cells
作者: Vijay, Natarajan
Balamurugan, Gopal
Venkatesan, Parthiban
Wu, Shu Pao
Velmathi, Sivan
應用化學系
Department of Applied Chemistry
公開日期: 1-九月-2017
摘要: A triple action chemosensor (R1) bearing a rhodamine and thiophene moiety was synthesized by a simple condensation reaction. The sensing behaviour and selectivity of the synthesized chemosensor toward metal ions were studied by UV-Vis and fluorescence spectroscopy. The chemosensor recognized Cu2+ and Cr3+ ions with significant changes in UV-Vis absorbance and fluorescence intensity. The results showed that Cr3+ induced greater fluorescence enhancement whereas Cu2+ ions bound strongly with the receptor by showing a strong absorption band at 554 nm but with weak fluorescence. A visible colour change was observed by the addition of Cu2+ and that colour change is due to the opening of the spirolactam ring triggered by the addition of Cu2+ ions. Job's plot analysis indicated a 1 : 2 and 1 : 1 binding stoichiometry between the chemosensor and Cr3+/Cu2+. Subsequently, the R1 - Cu2+ complex chemosensor was employed to detect CN- in the presence of different anions, such as F-, Cl-, Br-, I-, AcO-, H2PO4-, HSO4-, NO3- and -OH. In addition, the live cell imaging of HeLa cells using R1 and Cr3+ was demonstrated successfully.
URI: http://dx.doi.org/10.1039/c7pp00163k
http://hdl.handle.net/11536/146064
ISSN: 1474-905X
DOI: 10.1039/c7pp00163k
期刊: PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
Volume: 16
起始頁: 1441
結束頁: 1448
顯示於類別:期刊論文