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dc.contributor.authorPonnapalli, Kalyana Kumaren_US
dc.contributor.authorAdak, Avijit Kumaren_US
dc.contributor.authorDas, Anindyaen_US
dc.contributor.authorSong, Jen-Shinen_US
dc.contributor.authorWu, Szu-Hueien_US
dc.contributor.authorSun, Chung-Mingen_US
dc.contributor.authorLin, Chun-Chengen_US
dc.date.accessioned2018-08-21T05:54:31Z-
dc.date.available2018-08-21T05:54:31Z-
dc.date.issued2017-09-01en_US
dc.identifier.issn2193-5807en_US
dc.identifier.urihttp://dx.doi.org/10.1002/ajoc.201700148en_US
dc.identifier.urihttp://hdl.handle.net/11536/146075-
dc.description.abstractA protocol for the microwave-assisted Heck coupling reaction of C-aryl glycosides and styrenes has been developed for the synthesis of mono-and bis(C-glycoside) stilbenes. This method exclusively provides C-glycoside trans-stilbenes in good yields. The Pd-catalyzed Heck coupling re-action was successfully applied to various functionalized C-glycosyl aryl iodides and various substituted styrenes to deliver several C-glycoside trans-stilbenes with high selectivity. The obtained C-glycosyl trans-stilbenes were also examined for human SGLT-2 inhibitory activity.en_US
dc.language.isoen_USen_US
dc.subjectcross-couplingen_US
dc.subjectglycosylationen_US
dc.subjectinhibitorsen_US
dc.subjectmicrowave chemistryen_US
dc.subjectpalladiumen_US
dc.titletrans-Stilbene C-Glycosides: Synthesis by a Microwave-Assisted Heck Reaction and Evaluation of the SGLT-2 Inhibitory Activityen_US
dc.typeArticleen_US
dc.identifier.doi10.1002/ajoc.201700148en_US
dc.identifier.journalASIAN JOURNAL OF ORGANIC CHEMISTRYen_US
dc.citation.volume6en_US
dc.citation.spage1308en_US
dc.citation.epage1321en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000410778400026en_US
Appears in Collections:Articles


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