標題: Hypericin-mediated selective photomodification of connective tissues
作者: Hovhannisyan, V.
Hovhannisyan, A.
Ghukasyan, V.
Guo, H. W.
Chen, Y. F.
Lin, Hung-Ming
Chen, S. J.
Chen, Yang-Fang
Dong, C. Y.
光電學院
College of Photonics
關鍵字: Hypericin;collagen;SHG;biological imaging;multiphoton microscopy
公開日期: 1-Jan-2017
摘要: Hypericin (Hyp) has received attention due to its high phototoxicity against viruses and anti-tumor photoactivity. Using two-photon imaging, we demonstrated that Hyp induced photosensitized modification of collagen fibers in native tissues. Dynamics of photo-processes was monitored by time-lapse multiphoton imaging. We showed that Hyp-mediated processes in collagen tissues may be used for the selective modification of collagen fibers.
URI: http://dx.doi.org/10.1117/12.2255028
http://hdl.handle.net/11536/146709
ISSN: 0277-786X
DOI: 10.1117/12.2255028
期刊: PHOTONICS IN DERMATOLOGY AND PLASTIC SURGERY
Volume: 10037
Appears in Collections:Conferences Paper