標題: Oligonucleotides as 'bio-solvent' for in situ extraction and functionalisation of carbon nanoparticles
作者: Chen, Yu-Cheng
Wen, Cheng-Che
Liau, Ian
Hsieh, You-Zung
Hsu, Hsin-Yun
應用化學系
應用化學系分子科學碩博班
Department of Applied Chemistry
Institute of Molecular science
公開日期: 1-一月-2014
摘要: A simple yet novel one-pot approach is developed to prepare carbon nanoparticles with diameters of similar to 2 nm and modified by oligonucleotides. We use single-stranded deoxyribonucleic acid (ssDNA), which serves as a unique 'bio-solvent' for carbon nanoparticle (CNP) preparation and as a target molecule for functionalisation. Proposed interactions relevant to the stabilisation of the final oligonucleotide-CNP complex include pi-pi stacking and pi-HN bonding with sp(2) carbon atoms on the CNP surface. Furthermore, oligonucleotide-enriched CNPs can be readily extracted within seconds from a crude mixture of single-walled carbon nanotubes (SWCNTs) without any need for post-synthesis chemical modification. The established CNPs are biocompatible, possess intrinsic fluorescence, and do not result in the undesirable photobleaching effect, rendering them potential candidates for in vivo biological applications.
URI: http://dx.doi.org/10.1039/c4tb00314d
http://hdl.handle.net/11536/147695
ISSN: 2050-750X
DOI: 10.1039/c4tb00314d
期刊: JOURNAL OF MATERIALS CHEMISTRY B
Volume: 2
起始頁: 4100
結束頁: 4107
顯示於類別:期刊論文