完整後設資料紀錄
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lu, Guan-Ruei | en_US |
dc.contributor.author | Banerjee, Ansuman | en_US |
dc.contributor.author | Bhattacharya, Bhargab B. | en_US |
dc.contributor.author | Ho, Tsung-Yi | en_US |
dc.contributor.author | Chen, Hung-Ming | en_US |
dc.date.accessioned | 2019-04-02T06:00:34Z | - |
dc.date.available | 2019-04-02T06:00:34Z | - |
dc.date.issued | 2018-10-01 | en_US |
dc.identifier.issn | 1550-4832 | en_US |
dc.identifier.uri | http://dx.doi.org/10.1145/3229052 | en_US |
dc.identifier.uri | http://hdl.handle.net/11536/148789 | - |
dc.description.abstract | In the area of biomedical engineering, digital-microfluidic biochips (DMFBs) have received considerable attention because of their capability of providing an efficient and reliable platform for conducting point-of-care clinical diagnostics. System reliability, in turn, mandates error-recoverability while implementing biochemical assays on-chip for medical applications. Unfortunately, the technology of DMFBs is not yet fully equipped to handle error-recovery from various microfluidic operations involving droplet motion and reaction. Recently, a number of cyber-physical systems have been proposed to provide real-time checking and error-recovery in assays based on the feedback received from a few on-chip checkpoints. However, to synthesize robust feedback systems for different types of DMFBs, certain practical issues need to be considered such as co-optimization of checkpoint placement, error-recoverability, and layout of droplet-routing pathways. For application-specific DMFBs, we propose here an algorithm that minimizes the number of checkpoints and determines their locations to cover every path in a given droplet-routing solution. Next, for general-purpose DMFBs, where the checkpoints are pre-deployed in specific locations, we present a checkpoint-aware routing algorithm such that every droplet-routing path passes through at least one checkpoint to enable error-recovery and to ensure physical routability of all droplets. Furthermore, we also propose strategies for executing the algorithms in reliable mode to enhance error-recoverability. The proposed methods thus provide reliability-hardening mechanisms for a wide class of cyber-physical DMFBs. | en_US |
dc.language.iso | en_US | en_US |
dc.subject | Physical design automation | en_US |
dc.subject | checkpoint | en_US |
dc.subject | sensor | en_US |
dc.subject | droplet routing | en_US |
dc.subject | microfluidics | en_US |
dc.subject | biochips | en_US |
dc.title | Reliability Hardening Mechanisms in Cyber-Physical Digital-Microfluidic Biochips | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1145/3229052 | en_US |
dc.identifier.journal | ACM JOURNAL ON EMERGING TECHNOLOGIES IN COMPUTING SYSTEMS | en_US |
dc.citation.volume | 14 | en_US |
dc.contributor.department | 電子工程學系及電子研究所 | zh_TW |
dc.contributor.department | Department of Electronics Engineering and Institute of Electronics | en_US |
dc.identifier.wosnumber | WOS:000457140900003 | en_US |
dc.citation.woscount | 0 | en_US |
顯示於類別: | 期刊論文 |