Full metadata record
DC FieldValueLanguage
dc.contributor.authorChang, Chieh-Yuen_US
dc.contributor.authorLin, Yu-Huanen_US
dc.contributor.authorWu, Yen-Kuen_US
dc.date.accessioned2019-04-02T06:00:21Z-
dc.date.available2019-04-02T06:00:21Z-
dc.date.issued2019-01-25en_US
dc.identifier.issn1359-7345en_US
dc.identifier.urihttp://dx.doi.org/10.1039/c8cc09817den_US
dc.identifier.urihttp://hdl.handle.net/11536/148864-
dc.description.abstractThe direct N1-selective allylation of indoles with allylic alcohols has been accomplished by synergistic functions of palladium catalysts and titanium tetraisopropoxide. The site selectivity is notably different from that observed in other related transition metal-catalyzed approaches. This chemistry provides a facile route to a variety of allylated indoles in synthetically useful yields. The utility of this simple allylation reaction was demonstrated with the first total synthesis of (+)-N-(4-hydroxyprenyl)-cyclo(alanyltryptophyl), which was completed in five steps, starting from l-tryptophan methyl ester hydrochloride.en_US
dc.language.isoen_USen_US
dc.titlePalladium-catalyzed N1-selective allylation of indoles with allylic alcohols promoted by titanium tetraisopropoxideen_US
dc.typeArticleen_US
dc.identifier.doi10.1039/c8cc09817den_US
dc.identifier.journalCHEMICAL COMMUNICATIONSen_US
dc.citation.volume55en_US
dc.citation.spage1116en_US
dc.citation.epage1119en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000458544800022en_US
dc.citation.woscount0en_US
Appears in Collections:Articles